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  • Author: [Cambridge News]
    Title: The British Scientist, Dr H. C. Watson holds a model of a protein molecule
    Reference [Cambridge News]
    Year: [date unknown]
    Type: Science
    Subject: H. C. Watson lecturing at the Biophysical Society, New York, on proteins
    Keywords: H. C. Watson
    Photographs: H. C. Watson and model of a protein molecule


  • Author: Veitch, Andrew
    Title: Leading brain research centre to close
    Reference The Guardian, [date unknown]
    Year: [c. mid 1980s]
    Type: Funding
    Subject: The MRC plans to close the neurochemical pharmacology unit at Cambridge University Medical School
    Keywords: John Butterfield; Leslie Iverson; Angus Mackay; Neurochemical Pharmacology Unit
    Photographs:


  • Author: Veitch, Andrew
    Title: Job puzzle at doomed brain unit
    Reference The Guardian, [date unknown]
    Year: [c. mid 1980's]
    Type: Funding
    Subject: Staff at the Neurochemical Pharmacology Unit have been told it is to close because a new director has not been found
    Keywords: Piers Emson; Leslie Iversen; Neurochemical Pharmacology Unit
    Photographs:


  • Author: Devlin, Hannah
    Title: Alcohol can cause irreversible genetic damage to stem cells, says study
    Reference The Guardian 3 January 2018
    Year: 2018
    Type: Science
    Subject: Link between drinking and cancer clarified by study – led by KJ Patel’s group in the LMB’s PNAC Division – which indicates alcohol causes cancer by scrambling DNA in cells, eventually leading to mutations.
    Keywords: KJ Patel; alcohol; cancer; acetaldehyde; DNA damage; aldehyde dehydrogenase 2 (ALDH2); flushing mutation; stem cells; blood cells
    Photographs:


  • Author: Brackley, Paul
    Title: Magnetic attraction of AstraZeneca to MRC Laboratory of Molecular Biology
    Reference Cambridge Independent 8 January 2018
    Year: 2018
    Type: Biotechnology
    Subject: AstraZeneca has moved its Nuclear Magnetic Resonance laboratory to the LMB while its new global R&D centre is built nearby.
    Keywords: AstraZeneca; Maria Flocco; nuclear magnetic resonance (NMR); Hugh Pelham; David Neuhaus; Kevin Embrey; superconducting solenoid; Blue Skies; PAR; cancer; drug discovery; cryo-electron microscopy; consortium
    Photographs: David Neuhaus, and Kevin Embrey in the nuclear magnetic resonance (NMR) lab


  • Author: Davies, Emma
    Title: The rhythm of life
    Reference Education in Chemistry 11 January 2018
    Year: 2018
    Type: Science
    Subject: John O’Neill, from Cell Biology Division, discusses how unravelling the complex mechanisms of the body clock has led to some fascinating discoveries worthy of the 2017 Nobel Prize in Physiology or Medicine.
    Keywords: circadian rhythms; John O’Neill; Jeffrey Hall; Michael Rosbash; Michael Young; clock genes; PER; TIM protein; jet lag; suprachiasmatic nucleus (SCN)
    Photographs:


  • Author: Arney, Kat
    Title: Unlocking the secrets of the brain - From autism and schizophrenia to Alzheimer’s lab-grown mini-brains could be the key to solving the biggest mysteries about human development and disease
    Reference Science Focus 5 January 2018
    Year: 2018
    Type: Science
    Subject: Madeline Lancaster, from the LMB’s Cell Biology Division, discusses how lab-grown ‘mini-brains’ could be the key to solving the biggest mysteries about human brain development and disease.
    Keywords: Madeline Lancaster; ‘mini-brain’; organoids; brain stem cells; ‘rosettes’; ‘black box’; ‘brain Lego’; epilepsy; Alzheimer’s disease; telomeres; autism
    Photographs:


  • Author: International Society for Computational Biology (ISCB)
    Title: 2018 ISCB Innovator Award M. Madan Babu
    Reference ISCB 15 February 2018
    Year: 2018
    Type: Awards & Prizes
    Subject: The Award is given to a leading scientist who is within a decade and half of receiving their PhD degree, and has consistently made outstanding contributions to the field and continues to forge new directions.
    Keywords: Award; Madan Babu; ISCB innovator award; cellular regulation; signalling proteins;
    Photographs: Portrait of Madan


  • Author: Brackley, Paul
    Title: Dr Jan Löwe says he’s ‘humbled’ to take over as director of MRC Laboratory of Molecular Biology
    Reference Cambridge Independent 14 February 2018
    Year: 2018
    Type: Events and Celebrations
    Subject: Deputy Director, Jan Löwe, will be taking over from Hugh Pelham as Director of the LMB this spring
    Keywords: Jan Löwe; new director; Hugh Pelham; “excited and humbled”; ‘Nobel Prize factory’; Richard Henderson
    Photographs: Jan Löwe (LMB); Hugh Pelham (LMB); Building; Hugh Pelham with Richard Henderson; picture of crowds on an open day


  • Author: Knapton, Sarah
    Title: Alzheimer’s disease will become manageable like HIV, say award-winning scientists
    Reference The Telegraph 6 March 2018
    Year: 2018
    Type: Awards & Prizes
    Subject: 2018 Brain Prize winner Michel Goedert, group leader in the Neurobiology Division, who discovered the importance of tau protein in Alzheimer’s said he could see a time when dementia became a chronic illness like HIV.
    Keywords: Michel Goedert; Brain Prize; tau protein; Alzheimer’s; HIV; dementia; Lundbeck Foundation; amyloid; neurodegenerative disease; John Hardy; Bart De Strooper; Christian Haass
    Photographs:


  • Author: University of Cambridge - Department of Zoology
    Title: Regulation of DNA replication during early embryogenesis
    Reference University of Cambridge 5 March 2018
    Year: 2018
    Type: Science
    Subject: Julian Sale and collaborators from the Francis Crick Institute and the Department of Zoology have discovered and characterised a new macromolecular protein complex that is essential for rapid DNA replication and cleavage cycles in very early embryos.
    Keywords: Julian Sale; Xenopus laevis; Y RNS’s; xNuRD; embryos; replications; mid-blastula transition (MBT)
    Photographs:


  • Author: Woodmansey, David
    Title: Biomarker offers new hope for foot-and-mouth detector
    Reference Vet Times 13 March 2018
    Year: 2018
    Type: Science
    Subject: A new discovery by David Komander’s group and collaborators could allow scientists to detect animals infected with the foot-and-mouth disease virus (FMDV) and distinguish them from those that have been vaccinated.
    Keywords: David Komander; foot-and-mouth disease virus (FMDV); The Pirbright Institute; diagnostics; test; antiviral signalling; biomarker; vaccination
    Photographs:


  • Author: Ferry, Georgina
    Title: Obituary - John Sulston (1942-2018)
    Reference Nature 19 March 2018
    Year: 2018
    Type: Obituary
    Subject: Nature looks back at the life and work of John Sulston, from his time investigating cell fate, lineage and the genetics of C. elegans at the LMB, to his involvement with the Human Genome Project.
    Keywords: John Sulston; Human Genome Project; caenorhabditis elegans; Francis Crick; Sydney Brenner; Robert Horvitz; worm; Sanger Centre; The Common Thread; sequencing; cell death; Jim Watson
    Photographs: John Sulston in lab


  • Author: Brackley, Paul
    Title: Dr M Madan Babu of MRC LMB wins prize for insights into the machinery inside our cells
    Reference Cambridge Independent 21 March 2018
    Year: 2018
    Type: Awards & Prizes
    Subject: In the first year that the Blavatnik Awards for Young Scientists have been extended to the UK, M. Madan Babu is named Life Sciences Laureate for his work on the structure of proteins, including G-protein coupled receptors which are major drug targets, and disordered regions.
    Keywords: Blavatnik Award; Madan Babu; Life Sciences Laureate; G-protein coupled receptors (GCPRs); ‘intrinsically disordered regions’ IDR; computational biology; ‘pocket’; proteins; mutation
    Photographs: Five pictures of Madan and one with his group, taken around the building


  • Author: Brackley, Paul
    Title: Winner of Brain Prize 2018, Prof Michel Goedert, on our best hope for tackling Alzheimer’s disease
    Reference Cambridge Independent 24 March 2018
    Year: 2018
    Type: Awards & Prizes
    Subject: Michel Goedert, winner of Brain Prize 2018, believes our best hope of fighting Alzheimer’s disease lies in learning to predict who will get it and preventing it from developing in the first place.
    Keywords: Brain Prize; Michel Goedert; Alzheimer’s; neurodegenerative diseases; Claude Wischik; Tony Crowther; Michal Novak; John Walker; Cesar Milstein; Ross Jakes; Maria Grazia Spillantini; plaques; tangles; tau protein; prion-like; aggregates; beta-amyloid deposits; Richard Henderson; Sjors Scheres
    Photographs: Michel in and around the lab


  • Author: Bonflo, Claudia
    Title: How to find the right mentor for you
    Reference The Biochemist Blog 22 March 2018
    Year: 2018
    Type: Career Structure
    Subject: Claudia Bonfio, postdoc in the PNAC Division, shares personal experiences of finding the right mentor to help her through the transition from PhD student to postdoc.
    Keywords: Claudia Bonflo; Postdoc; mentor; Royal Society of Chemistry (RSC); PhD students; early-career; ‘Postdoctoral Training Scheme’
    Photographs: Claudia with her research goup


  • Author: Ball, Philip
    Title: Why two brains are better than one
    Reference The Guardian 31 March 2018
    Year: 2018
    Type: Science
    Subject: Philip Ball, science writer at The Guardian, has had a ‘mini-brain’ grown from a sample of skin from his arm. He talks to the Madeline Lancaster, and others, to find out how scientists are using such organoids to understand brain growth and disease
    Keywords: Madeline Lancaster; neurodegenerative disease; mini-brains; Alzheimer’s; tissue; stem cells; fibroblasts; embryo research; “pluripotency”; Shinya Yamanaka; induced pluripotent stem cells (iPSCs); tau proteins
    Photographs:


  • Author: Bonflo, Claudia
    Title: How to be better at networking at conferences
    Reference The Biochemist Blog 15 May 2018
    Year: 2018
    Type: Career Structure
    Subject: Claudia Bonfio, postdoc in the PNAC Division, shares her top tips on how to enjoy and get the most out of networking at academic conferences.
    Keywords: Claudia Bonflo; Postdoc; collaborations; academic conference; networking
    Photographs:


  • Author: Williams, Thomas
    Title: First person - Thomas Williams
    Reference Journal of Cell Science 23 May 2018
    Year: 2018
    Type: Career Structure
    Subject: ‘First Person’ interview postdoc Thomas Williams about his recent paper, research challenges, mentoring & advice for Early Career Researchers.
    Keywords: Thomas Williams; Robert Kay; macropinocytosis (cell drinking); Dictyostelium amoebae; flow cytometry; Douwe Veltman; mentor; dehydrated toe
    Photographs: Thomas Williams in the mountains


  • Author: Brownlee, George G.
    Title: The Legacy of Fred Sanger - 100 Years on from 1918
    Reference Journal of Molecular Biology 29 May 2018
    Year: 2018
    Type: Historical - Reminiscences
    Subject: This August marks the centenary of the birth of Fred Sanger, LMB alumnus and one of the most influential scientists of the twentieth century.This article reflects on Fred’s history and the history of the LMB, including documents from the LMB Archive.
    Keywords: Fred Sanger; centenary; DNA sequencing; genetics; insulin; Amino acid; fluorodini- trobenzene; Sanger reagent; genomes; “Conscientious Objector”; Alan Coulson; Quaker; Order of Merit; Max Perutz; Cavendish laboratory; proteins
    Photographs: Fred Sanger at his bench (LMB)


  • Author: Crockett, Moya
    Title: Scientist Madeline Lancaster is on a mission to understand how our brains really work
    Reference Stylist 1 June 2018
    Year: 2018
    Type: Career Structure
    Subject: ‘Woman of the Week’ is Stylist Magazine’s weekly celebration of women making a difference to society.Madeline Lancaster has spent her career researching the human brain – and her research could have a huge effect on how we understand our own minds.
    Keywords: Madeline Lancaster; Alzheimer’s; Parkinson’s; ‘mini-brains’; stem cells; cerebral organoids; neurons
    Photographs: Madeline Lancaster in lab


  • Author: Masson, Glenn
    Title: A parliamentary lab meeting
    Reference MRC insight 13 June 2018
    Year: 2018
    Type: Events and Celebrations
    Subject: Glenn Masson, postdoc in the PNAC Division, took part in this year’s Royal Society Parliamentary Pairing Scheme. Read Glenn’s blog to find out more about his experience on the scheme.
    Keywords: Glenn Masson; Daniel Zeichner MP; Royal Society’s Parliamentary Pairing Scheme; funding; structural mass spectrometry; Jan Lowe; research; shadow; return visit
    Photographs: Glenn Masson showing Daniel Zeichner MP around the lab. (LMB)


  • Author: Media Team
    Title: Sarah Teichmann awarded the Genetics Society’s 2018 Mary Lyon Medal
    Reference Wellcome Sanger Institute 29 January 2018
    Year: 2018
    Type: Alumni
    Subject: Sarah Teichamnn has received the Genetics Society’s prestigious Mary Lyon Medal 2018 for “outstanding research” in understanding how the immune system works by using genomics and bioinformatics approaches.
    Keywords: Sarah Teichmann; Wellcome Sanger Institute; Mary Lyon Medal; Genetics; alumni; immune system; award
    Photographs: Sarah Teichmann


  • Author: Nagley, Phillip
    Title: Winner of 2018 FAOBMB Young Scientist Award (Male)
    Reference Federation of Asian and Oceanian Biochemists and Molecular Biologists 1 February 2018
    Year: 2018
    Type: Alumni
    Subject: Dr Varodom Charoensawan, former PhD student in the Structural Studies Division, has been awarded the FAOBMB Young Scientist Award for his work on the systems regulating gene expression.
    Keywords: Varodom Charoensawan; alumni; award; Newton Advanced Fellowship; structural studies; systems biology; FAOBMB
    Photographs: Image of Varodom Charoensawan


  • Author: Dutchen, Stephanie
    Title: BCMP Welcomes Alan Brown
    Reference Harvard Medical School 27 February 2018
    Year: 2018
    Type: Alumni
    Subject: Alan Brown reflects on taking on the position of Assistant Professor at Harvard Medical School, his new research focus and how he first became interested in science.
    Keywords: Alan Brown; Harvard Medical School; organelle; cilium; cryo-EM
    Photographs:


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