Murzin, A.G. (2008)
Biochemistry: Metamorphic proteins
Science 320 (5884): 1725-1726.
Andreeva, A., Howorth, D., Chandonia, J.-M., Brenner, S.E., Hubbard, T.J.P., Chothia, C., Murzin, A.G. (2008)
Data growth and its impact on the SCOP database: New developments
Nucleic Acids Research 36 (SUPPL. 1): D419-D425.
Andreeva, A., Murzin, A.G. (2006)
Evolution of protein fold in the presence of functional constraints
Curr. Opin. Struct. Biol.16 (3): 399-408.
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Group Members
- Antonina Andreeva
- David Howorth
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 The Structural Classification of Proteins (SCOP http://scop.mrc-lmb.cam.ac.uk/scop/) is the ongoing project established in 1994. We produce and maintain the SCOP database, a “periodic table” of proteins that provides a detailed and comprehensive description of the relationships of all known protein structures.
Now we aim to realise the potential of SCOP to become an essential resource for the functional annotation of novel proteins characterised by structural genomics, as it has done previously for other areas of bioinformatics and computational biology.
We also explore new insights into protein folding and evolution, suggested by non-trivial relationships discovered during the classification of new protein families in SCOP.
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Group Leaders 
