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Publications

2009

Rosado IV, Niedzwiedz W, Alpi AF, Patel KJ (2009) 'The Walker B motif in avian FANCM is required to limit sister chromatid exchanges but is dispensable for DNA crosslink repair'. Nucleic acids research 37 (13) 4360 -70.

Xhang XY, Langenick J, Traynor D, Babu M, Kay R, Patel KJ (2009) 'XPF and not the Fanconi anaemia or the TLS polymerase Rev3 is responsible for extreme sensitivity to cisplatin in Dictyostelium Discoideum'. PLOS Genetics 5 (9).

2008

Alpi AF, Pace PE, Babu MM, Patel KJ (2008) 'Mechanistic insight into site-restricted monoubiquitination of FANCD2 by Ube2t, FANCL, and FANCI.' Molecular Cell 32(6): 767-777.

Alpi AF and Patel K.J (2008) 'Monoubiquitylation in the Fanconi anemia DNA damage response pathway.' DNA Repair (Amst). 2009 Apr 5;8(4):430-5.

2007

Patel KJ (2007). 'Fanconi anemia and breast cancer susceptibility.' Nature Genetics. 2 (39): 142-143

Patel KJ and Joenje H (2007). 'Fanconi anemia and DNA replication repair.' DNA repair. 6: 885-890

Alpi A, Langevin F, Mosedale M,  Muchida Y, Datta A and Patel K J 'UBE2T, the FA core complex and FANCD2 are recruited independently to chromatin: A basis for the regulation of FANCD2 monoubiquitination' (2007). Molecular and Cellular Biology 27. (24): 8421-8430

Oestergaard V, Langevin F, Kuiken H, Pace P, Niedzwiedz W, Simpson L, Ohzeki M, Takata M, Sale J and Patel K.J 'Deubiquitination of FANCD2 is required for DNA crosslink repair' (2007). Molecular Cell 28 (5): 798-809

2006

Simpson LJ, Ross AL, Szüts D, Alviani A, Oestergaard VH, Patel KJ and Sale JE (2006). 'RAD18-independent ubiquitination of proliferating-cell nuclear antigen in the avian cell line DT40.' EMBO Reports. 7 (9): 927-932

2005

Niedzwiedz W and Patel K.J (2005). 'Dubbing a tumour suppressor pathway' Cancer Cell. Feb;7(2). 114-115.

Mosedale G, Niedzwiedz W, Alpi A, Perrina F, Leal J, Langevin F, Johnson M, Pace P and Patel K.J (2005). 'The Vertebrate Hef orthologue is a component of the Fanconi Anaemia tumour suppressor pathway.' Nature Structural and Molecular Biology. 12 (9):763-771.

2004

Niedzwiedz W, Mosedale G, Johnson M, Ong C, Pace P, and Patel K.J (2004). 'The Fanconi anemia gene FANCC promotes homologous recombination and error prone DNA repair.' Molecular Cell. 15. 607-620.

2003

Vandenberg C, Gergely F, Ong C, Pace P, Mallery D, Hiom K, and Patel K.J. (2003). 'BRCA1- Independent Ubiquitination of FANCD2.' Molecular Cell. 12, 247-254.

2002

Pace P,Johnson M,Tan WMT, Mosedale G, Sng C, Hoatlin M, deWinter J, Joenje H, Gergely F and Patel K.J (2002). 'FANCE : The link between Fanconi anaemia complex assembly and activity'. EMBOJ. 21. 13, 3414-3423.

2001

Joenje H and Patel K.J (2001). The emerging genetic and molecular basis of Fanconi Aneamia. Nat.Rev. Gen 2, 446-457.

1998

Patel.K.J, Yu.V, Lee.H.L, Corcoran..A, Thistlewaite. F.C, Evans. M, Colledge.W, Friedman. L, Ponder. B.A.J and Venkitaraman. A.R. (1998). 'Involvement of Brca2 in DNA repair'. Molecular Cell. 1, 347-357.

Friedman.L, Thistlewaite. F.C, Patel. K.J, Yu.V, Lee. H.L, Venkitaraman. A.R, Colledge. W, Evans. M, and Ponder. B.A.J. (1998). 'Thymic Lymphomas in mice with a truncating mutation in Brca2'. Cancer Research. 53. 1558

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