Publications

M. Freeman, P. N. Rather (2008) Intercellular signalling by rhomboids in eukaryotes and prokaryotes, Winans, S.C, B. L. Bassler, Eds. ASM Press, Washington DC, (2008), pp. 431-442

Freeman, M. (2008). Rhomboid proteases and their biological functions. Annu Rev Genet 42, 191-210.

Freeman, M., and St Johnston, D. (2008). Wherefore DMM? Disease Models & Mechanisms 1, 6-7.

Mao, Y., Kerr, M., and Freeman, M. (2008). Modulation of Drosophila retinal epithelial integrity by the adhesion proteins capricious and tartan. PLoS ONE 3, e1827.

Escudero, L.M. and Freeman, M. (2007). Mechanism of G1 arrest in the Drosophila eye imaginal disc. BMC Developmental Biology 7, 13

Stevenson LG, Strisovsky K, Clemmer KM, Bhatt S, Freeman M, Rather PN (2007) The rhomboid protease AarA mediates quorum sensing in Providencia stuartii by activating TatA of the twin-arginine translocase. Proc Natl Acad Sci U S A 104, 1003-1008.

Brown KE, Kerr M, Freeman M (2007) The EGFR ligands Spitz and Keren act cooperatively in the Drosophila eye. Developmental Biology, 307, 105-113.

Lemberg, M.K. and Freeman, M. (2007) Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases. Genome Research, doi gr.6425307 [pii] 10.1101/gr.6425307

Escudero, L.M., Bischoff, M. and Freeman, M. (2007) Myosin II regulates complex cellular arrangement and epithelial architecture in Drosophila. Developmental Cell, 13, 717-29

Lemberg, M. K., and Freeman, M. (2007). Cutting proteins within lipid bilayers: rhomboid structure and mechanism. Molecular Cell, 28, 930-40.

Charroux, B., Freeman, M., Kerridge, S., and Baonza, A. (2006). Atrophin contributes to the negative regulation of epidermal growth factor receptor signalling in Drosophila. Developmental Biology, 291, 278-90.

McQuibban, G.A., Lee J.R., Zheng, L., Juusola, M. and Freeman, M. (2006). Normal mitochondrial dynamics requires Rhomboid-7 and affects Drosophila lifespan and neuronal function. Current Biology,16, 982-989.

Brown, K.E., Baonza, A. and Freeman, M. (2006). Epithelial cell adhesion in the developing Drosophila retina is regulated by Atonal and the EGF receptor pathway. Developmental Biology 300, 710-721.

Freeman, M. (2006). Enigmatic enzymes revealed (News and Views). Nature 444, 153-155.