We investigate how mammalian oocytes develop and how they mature into fertilizable eggs.
To become a fertilizable egg, an oocyte has to eliminate half of the chromosomes into a small polar body, because the other half will be contributed by the sperm during fertilization. It is very important that we better understand this process, because errors during chromosome elimination result in aneuploid embryos and thus miscarriages, genetic disorders, or infertility.
Please use the links above to find out more about meiosis, our research and us.
Have you ever seen a live mammalian oocyte mature into a fertilizable egg? If not: click here!
We currently have Post-doc and PhD positions available. Please contact Melina if you are interested in joining the lab.