LMB In The News


BBC Documentary: Inside My Brain

Charlotte Church is on a scientific journey to explore the cutting edge of mental health research. As part of this, she meets Madeline Lancaster, from the LMB’s Cell Biology Division, to learn about how the lab grows ‘mini brains’ and uses them to study brain development and disease. More…

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The Science Show – interview with Lori Passmore

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Lori Passmore, from the LMB’s Structural Studies Division, is interviewed for The Science Show on Cambridge 105 Radio. This monthly programme showcases leading scientific figures from Cambridge, exploring how they got into a life dedicated to discovery and understanding. More

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What are mini brains?

Shielded by our thick skulls and swaddled in layers of protective tissue, the human brain is extremely difficult to observe in action. Luckily, scientists can use brain organoids – pencil-eraser-sized masses of cells that function like human brains but aren’t part of an organism – to look closer. Madeline Lancaster, from the LMB’s Cell Biology Division, discusses how this is done and whether it is ethical through a video created by TED-Ed. More…

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Unlocking the secrets of the brain

Madeline Lancaster, from the LMB’s Cell Biology Division, discusses how lab-grown ‘mini-brains’ could be the key to solving the biggest mysteries about human brain development and disease. More…

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The circadian rhythm of life

John O’Neill, from the LMB’s Cell Biology Division, discusses how unravelling the complex mechanisms of the body clock has led to some fascinating discoveries worthy of the 2017 Nobel Prize in Physiology or Medicine. More

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Magnetic attraction of AstraZeneca to MRC LMB

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AstraZeneca has moved it Nuclear Magnetic Resonance laboratory to the LMB while its new global R&D centre is built nearby. More

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Alcohol can cause irreversible genetic damage to stem cells, says study

Link between drinking and cancer clarified by study – led by KJ Patel’s group in the LMB’s PNAC Division – which indicates alcohol causes cancer by scrambling DNA in cells, eventually leading to mutations. More…

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Scientists establish a comprehensive protein interactions map of the replication machinery of a chronic virus

Chronic viral infections are amongst the biggest threats to human health worldwide. Leo James’ group from the LMB’s PNAC Division, in collaboration with scientists at the Austrian Academy of Sciences and University of Basel, have established the first comprehensive overview of cellular proteins interacting with the LCMV polymerase. It is hoped that the research leads to a better understanding of how chronic viral infections start and the complex molecular interactions between viruses and their hosts. More…

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Distinct human mutations can alter the effect of medicine

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About one third of all medicine binds to the same type of receptor in the human body. An estimated 3 percent of the population have receptors of this type that are so genetically different that they are predisposed to altered, ineffective or adverse responses to medicine, a new study from the University of Copenhagen and the MRC Laboratory of Molecular Biology in Cambridge shows. More…

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GPCR structures aided drug design

Chemical & Engineering News (C&EN)

A decade after a key structural analysis, scientists have a better understanding of the pharmaceutically important family of receptor proteins – G protein-coupled receptors (GPCR).  Includes reference to the work done at the LMB by Chris Tate. More...

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