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The assembly of the human signal recognition particle (SRP)

The S domain of human 7SL RNA undergoes a striking conformational change during the assembly of human signal recognition paricle (SRP). Human 7SL RNA in complex with M. jannaschii SRP19 (Oubridge et al., Molecular Cell 9, 1251-1261 (2002)) and in complex with human SRP19 and the M domain of SRP54 (Kuglstatter et al., Nature Structural Biology 9, 740-744 (2002)
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last updated on 19 July 2007