{"id":955,"date":"2023-12-14T15:36:42","date_gmt":"2023-12-14T15:36:42","guid":{"rendered":"https:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/baum\/?p=955"},"modified":"2025-09-18T13:55:48","modified_gmt":"2025-09-18T13:55:48","slug":"andriko-von-kugelgen","status":"publish","type":"post","link":"https:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/baum\/andriko-von-kugelgen\/","title":{"rendered":"Andriko von K\u00fcgelgen"},"content":{"rendered":"\n
\"\"<\/figure><\/div><\/div>

Andriko von K\u00fcgelgen<\/h2>

<\/p>

I studied biochemistry in T\u00fcbingen after which I moved to the University of Oxford where I joined Tanmay Bharat’s lab for my PhD. During my PhD studies I investigated archaeal and bacterial cell surface proteins using cryo electron tomography and subtomogram averaging.

I am interested in studying the interactions of archaea and bacteria in complex microbial communities within biofilms.<\/div>
    <\/ul><\/div><\/div>\n\n\n\n

    Publications<\/h2>\n\n\n\n

    Selected publications: <\/strong>                                                                                          <\/p>\n\n\n\n

    1.         von K\u00fcgelgen, A.<\/strong>, Cassidy, C.K., van Dorst, S., Pagani, L.L., Batters, C., Ford, Z., L\u00f6we, J., Alva, V., Stansfeld, P.J., and Bharat, T.A.M., “Membraneless channels sieve cations in ammonia-oxidizing marine archaea”.<\/em> Nature<\/strong>, (2024<\/em>). 630(8015): p. 230-236.<\/p>\n\n\n\n

    2.         von K\u00fcgelgen, A.<\/strong>, Tang, H., Hardy, G.G., Kureisaite-Ciziene, D., Brun, Y.V., Stansfeld, P.J., Robinson, C.V., and Bharat, T.A.M., “In Situ<\/em> Structure of an Intact Lipopolysaccharide-Bound Bacterial Surface Layer”.<\/em> Cell<\/strong>, (2020<\/em>). 180(2): p. 348-358 e15.<\/p>\n\n\n\n

    3.         von K\u00fcgelgen, A.<\/strong>, Alva, V., and Bharat, T.A.M., “Complete atomic structure of a native archaeal cell surface”.<\/em> Cell Reports<\/strong>, (2021<\/em>). 37(8): p. 110052.<\/p>\n\n\n\n

    4.         von K\u00fcgelgen, A.<\/strong>, van Dorst, S., Alva, V., and Bharat, T.A.M., “A multidomain connector links the outer membrane and cell wall in phylogenetically deep-branching bacteria”.<\/em> PNAS<\/strong>, (2022<\/em>). 119(33): p. e2203156119.<\/p>\n\n\n\n

    5.         von K\u00fcgelgen, A.<\/strong>, van Dorst, S., Yamashita, K., Sexton, D.L., Tocheva, E.I., Murshudov, G., Alva, V., and Bharat, T.A.M., “Interdigitated immunoglobulin arrays form the hyperstable surface layer of the extremophilic bacterium Deinococcus radiodurans<\/em>“.<\/em> PNAS<\/strong>, (2023<\/em>). 120(16): p. e2215808120.<\/p>\n\n\n\n

    All  publications:<\/strong><\/p>\n\n\n\n

    6.         Herdman, M.*, von K\u00fcgelgen, A.<\/strong>*<\/strong>, Kureisaite-Ciziene, D., Duman, R., El Omari, K., Garman, E.F., Kjaer, A., Kolokouris, D., Lowe, J., Wagner, A., Stansfeld, P.J., and Bharat, T.A.M., “High-resolution mapping of metal ions reveals principles of surface layer assembly in Caulobacter crescentus<\/em> cells”.<\/em> Structure<\/strong>, (2022<\/em>). 30(2): p. 215-228 e5.<\/p>\n\n\n\n

    7.         Tarafder, A.K., von K\u00fcgelgen, A.<\/strong>, Mellul, A.J., Schulze, U., Aarts, D., and Bharat, T.A.M., “Phage liquid crystalline droplets form occlusive sheaths that encapsulate and protect infectious rod-shaped bacteria”.<\/em> PNAS<\/strong>, (2020<\/em>). 117(9): p. 4724-4731.<\/p>\n\n\n\n

    8.         Chorev, D.S., Tang, H., Rouse, S.L., Bolla, J.R., von K\u00fcgelgen, A.<\/strong>, Baker, L.A., Wu, D., Gault, J., Gr\u00fcnewald, K., Bharat, T.A.M., Matthews, S.J., and Robinson, C.V., “The use of sonicated lipid vesicles for mass spectrometry of membrane protein complexes”.<\/em> Nature Protocol<\/strong>, (2020<\/em>). 15(5): p. 1690-1706.<\/p>\n\n\n\n

    9.         Bharat, T.A.M., von K\u00fcgelgen, A.<\/strong>, and Alva, V., “Molecular Logic of Prokaryotic Surface Layer Structures”.<\/em> Trends in Microbiology<\/strong>, (2021<\/em>). 29(5): p. 405-415.<\/p>\n\n\n\n

    10.      Krause, S.*, Gfrerer, S.*, von K\u00fcgelgen, A.<\/strong>, Reuse, C., Dombrowski, N., Villanueva, L., Bunk, B., Sproer, C., Neu, T.R., Kuhlicke, U., Schmidt-Hohagen, K., Hiller, K., Bharat, T.A.M., Rachel, R., Spang, A., and Gescher, J., “The importance of biofilm formation for cultivation of a Micrarchaeon and its interactions with its Thermoplasmatales<\/em>host”.<\/em> Nature Communications<\/strong>, (2022<\/em>). 13(1): p. 1735.<\/p>\n\n\n\n

    11.      B\u00f6hning, J., Dobbelstein, A.W. *, Sulkowski, N.*, Eilers, K., von K\u00fcgelgen, A.<\/strong>, Tarafder, A.K., Peak-Chew, S.Y., Skehel, M., Alva, V., Filloux, A., and Bharat, T.A.M., “Architecture of the biofilm-associated archaic Chaperone-Usher pilus CupE from Pseudomonas aeruginosa<\/em>“.<\/em> PLoS Pathogens<\/strong>, (2023<\/em>). 19(4): p. e1011177.<\/p>\n\n\n\n

    12.      Zivanov, J.*, Ot\u00f3n, J.*, Ke, Z., von K\u00fcgelgen, A.<\/strong>, Pyle, E., Qu, K., Morado, D., Castano-Diez, D., Zanetti, G., Bharat, T.A.M., Briggs, J.A.G., and Scheres, S.H.W., “A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0”.<\/em> eLife<\/strong>, (2022<\/em>). 11.<\/p>\n\n\n\n

    13.      Herdman, M., Isbilir, B., von K\u00fcgelgen, A.<\/strong>, Schulze, U., Wainman, A., and Bharat, T.A.M., “Cell cycle dependent coordination of surface layer biogenesis in Caulobacter crescentus”.<\/em> Nature Communications<\/strong>, (2024<\/em>). 15(1): p. 3355.<\/p>\n\n\n\n

    14.      Burt, A.*, Toader, B.*, Warshamanage, R., von K\u00fcgelgen, A.<\/strong>, Pyle, E., Zivanov, J., Kimanius, D., Bharat, T.A.M., and Scheres, S.H.W., “An image processing pipeline for electron cryo-tomography in RELION-5”.<\/em> FEBS Open Bio<\/strong>, (2024<\/em>).<\/p>\n\n\n\n

    15.      Hamm, J.N. *, Liao, Y.*, von K\u00fcgelgen, A.<\/strong>, Dombrowski, N., Landers, E., Brownlee, C., Johansson, E.M.V., Whan, R.M., Baker, M.A.B., Baum, B., Bharat, T.A.M., Duggin, I.G., Spang, A., and Cavicchioli, R., “The parasitic lifestyle of an archaeal symbiont”.<\/em> Nature Communications<\/strong>, (2024<\/em>). 15(1): p. 6449.<\/p>\n","protected":false},"excerpt":{"rendered":"

    Publications Selected publications:                                                                                            1.         von K\u00fcgelgen, A., Cassidy, C.K., van Dorst, S., Pagani, L.L., Batters, C., Ford, Z., L\u00f6we, J., Alva, V., Stansfeld, P.J., and Bharat, T.A.M., “Membraneless channels sieve cations in ammonia-oxidizing marine archaea”. Nature, (2024). 630(8015): p. 230-236. 2.         von K\u00fcgelgen, A., Tang, H., Hardy, G.G., Kureisaite-Ciziene, D., Brun, Y.V., Stansfeld, P.J., Robinson, C.V., and Bharat, […]<\/p>\n","protected":false},"author":1,"featured_media":957,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_genesis_hide_title":false,"_genesis_hide_breadcrumbs":false,"_genesis_hide_singular_image":false,"_genesis_hide_footer_widgets":false,"_genesis_custom_body_class":"","_genesis_custom_post_class":"","_genesis_layout":"","footnotes":""},"categories":[14],"tags":[],"class_list":{"0":"post-955","1":"post","2":"type-post","3":"status-publish","4":"format-standard","5":"has-post-thumbnail","7":"category-lab-associates","8":"entry"},"featured_image_src":"https:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/baum\/wp-content\/uploads\/sites\/36\/2023\/12\/Andriko_website-580x400.png","featured_image_src_square":"https:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/baum\/wp-content\/uploads\/sites\/36\/2023\/12\/Andriko_website-580x600.png","author_info":{"display_name":"","author_link":"https:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/baum\/author\/"},"_links":{"self":[{"href":"https:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/baum\/wp-json\/wp\/v2\/posts\/955","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/baum\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/baum\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/baum\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/baum\/wp-json\/wp\/v2\/comments?post=955"}],"version-history":[{"count":8,"href":"https:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/baum\/wp-json\/wp\/v2\/posts\/955\/revisions"}],"predecessor-version":[{"id":2000,"href":"https:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/baum\/wp-json\/wp\/v2\/posts\/955\/revisions\/2000"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/baum\/wp-json\/wp\/v2\/media\/957"}],"wp:attachment":[{"href":"https:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/baum\/wp-json\/wp\/v2\/media?parent=955"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/baum\/wp-json\/wp\/v2\/categories?post=955"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www2.mrc-lmb.cam.ac.uk\/groups\/baum\/wp-json\/wp\/v2\/tags?post=955"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}