2014
Beale, R., Wise, H., Bloor, S., Ravenhill, B., Digard, P., Randow, F. (2014). A LIR motif in Influenza A virus M2 is required for virion stability. Cell Host & Microbe 15, 239-247.
Randow, F., and Youle, R.J. (2014). Self and Nonself: How Autophagy Targets Mitochondria and Bacteria. Cell Host and Microbe 15, 403–411.
2013
Randow, F., MacMicking, J.D., and James, L.C. (2013). Cellular self-defense: how cell-autonomous immunity protects against pathogens. Science 340, 701–706.
Li, S., Wandel, M.P., Li, F., Liu, Z., He, C., Wu, J., Shi, Y., and Randow, F. (2013). Sterical hindrance promotes selectivity of the autophagy cargo receptor NDP52 for the danger receptor galectin-8 in antibacterial autophagy. Science Signaling 6, ra9. (listen to podcast)
Muhlinen, von, N., Akutsu, M., Ravenhill, B.J., Foeglein, A., Bloor, S., Rutherford, T.J., Freund, S.M.V., Komander, D., and Randow, F. (2013). An essential role for the ATG8 ortholog LC3C in antibacterial autophagy. Autophagy 9, 784–786.
Boyle, K.B., and Randow, F. (2013). The role of “eat-me” signals and autophagy cargo receptors in innate immunity. Current Opinion in Microbiology 16, 1–10.
2012
Muhlinen, von, N., Akutsu, M., Ravenhill, B.J., Foeglein, A., Bloor, S., Rutherford, T.J., Freund, S.M.V., Komander, D., and Randow, F. (2012). LC3C, Bound Selectively by a Noncanonical LIR Motif in NDP52, Is Required for Antibacterial Autophagy. Molecular Cell 48, 329–342.
Thurston, T., Wandel, M., von Muhlinen, N., Foeglein, Á., and Randow, F. (2012). Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion. Nature 482, 414–418.
Randow, F., and Münz, C. (2012). Autophagy in the regulation of pathogen replication and adaptive immunity. Trends in Immunology 33, 475–487.
2011
Randow, F. (2011) How cells deploy ubiquitin and autophagy to defend their cytosol from bacterial invasion. Autophagy 7, 304-309.
Unterholzner, L., Sumner, R. P., Baran, M., Ren, H., Mansur, D. S., Bourke, N. M., Randow, F., Smith, G. L., and Bowie, A. G. (2011). Vaccinia Virus Protein C6 Is a Virulence Factor that Binds TBK-1 Adaptor Proteins and Inhibits Activation of IRF3 and IRF7. PLoS Pathog 7, e1002247.
2010
Bloor S, Maelfait J, Krumbach R, Beyaert R, Randow F. (2010) Endoplasmic reticulum chaperone gp96 is essential for infection with vesicular stomatitis virus. Proc Natl Acad Sci U S A, 6970-5.
von Muhlinen N, Thurston T, Ryzhakov G, Bloor S, Randow F. (2010) NDP52, a novel autophagy receptor for ubiquitin-decorated cytosolic bacteria. Autophagy, 288-289.
2009
Thurston, T., Ryzhakov, G., Bloor, S., von Muhlinen, N., and Randow, F. (2009). The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria. Nat Immunol, 1215-1221.
Randow, F., and Lehner, P. J. (2009). Viral avoidance and exploitation of the ubiquitin system. Nat Cell Biol, 527-534.
Rahighi, S., Ikeda, F., Kawasaki, M., Akutsu, M., Suzuki, N., Kato, R., Kensche, T., Uejima, T., Bloor, S., Komander, D., Randow, F., Wakatsuki, S., Dikic, I. (2009). Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-kB Activation. Cell, 1098-1109.
2008
Krumbach, R., Bloor, S., Ryzhakov, G., and Randow, F. (2008). Somatic cell genetics for the study of NF-kappaB signaling in innate immunity. Science Signal 1, pt7.
Bloor, S., Ryzhakov, G., Wagner, S., Butler, P. J., Smith, D. L., Krumbach, R., Dikic, I., and Randow, F. (2008). Signal processing by its coil zipper domain activates IKKgamma. Proc Natl Acad Sci U S A 105, 1279-1284.
Chen, R.A., Ryzhakov, G., Cooray, S., Randow, F., and Smith, G.L. (2008). Inhibition of IkappaB Kinase by Vaccinia Virus Virulence Factor B14. PLoS Pathog 4, e22.
Sarris, M., Andersen, K.G., Randow, F., Mayr, L., and Betz, A.G. (2008). Neuropilin-1 expression on regulatory T cells enhances their interactions with dendritic cells during antigen recognition. Immunity 28, 402-413.
2007
Ryzhakov, G., and Randow, F. (2007). SINTBAD, a novel component of innate antiviral immunity, shares a TBK1-binding domain with NAP1 and TANK. Embo J 26, 3180-3190.
selected older publications
Moore, K. J., Rosen, E. D., Fitzgerald, M. L., Randow, F., Andersson, L. P., Altshuler, D., Milstone, D. S., Mortensen, R. M., Spiegelman, B. M., and Freeman, M. W. (2001). The role of PPAR-gamma in macrophage differentiation and cholesterol uptake. Nat Med 7, 41-47.
Randow, F., and Seed, B. (2001). Endoplasmic reticulum chaperone gp96 is required for innate immunity but not cell viability. Nat Cell Biol 3, 891-896.
Docke, W. D., Randow, F., Syrbe, U., Krausch, D., Asadullah, K., Reinke, P., Volk, H. D., and Kox, W. (1997). Monocyte deactivation in septic patients: restoration by IFN-gamma treatment. Nat Med 3, 678-681.
Randow, F., Syrbe, U., Meisel, C., Krausch, D., Zuckermann, H., Platzer, C., and Volk, H. D. (1995). Mechanism of endotoxin desensitization: involvement of interleukin 10 and transforming growth factor beta. J Exp Med 181, 1887-1892.
