“First Alzheimer’s patient treated with BAN2401, a novel antibody targeting the neurotoxin believed to cause Alzheimer’s disease… Antibody humanization, also known as CDR-grafting (CDR is a synonym for complementarity determining region) was first invented at the MRC Laboratory of Molecular Biology in the UK by Dr. Sir Greg Winter and patented by the MRC in […]
LMB In The News
BBC Look East ‘Topping out’ of MRC Laboratory in Cambridge
“The coverage of the ‘Topping Out’ ceremony shown on BBC Look East can be seen by clicking on the more link.” More …
Cambridge research key to UK economy, says Minister
“The Minister also attended a topping out ceremony at the new £200m building for the Medical Research Council Laboratory of Molecular Biology in Cambridge. The new building, due to open in 2012, will provide first class facilities to some of the world’s leading scientists and stands as the flagship building for the extension of the […]
Secrets of the shaking palsy
“Parkinson’s disease might have much in common with Alzheimer’s disease, prion diseases and other protein-aggregation disorders… Like many other researchers, Goedert [LMB] now suspects that α-synuclein aggregation is the primary event in Parkinson’s disease — perhaps triggered by toxins or other environmental factors inside the intestines and sinuses. Most of the pathology in the brain […]
Body clock drugs could ease psychiatric disorders and jet lag
“Researchers have successfully used a drug to reset and restart the natural 24 hour body clock of mice in the lab. The ability to do this in a mammal opens up the possibility of dealing with a range of human difficulties including some psychiatric disorders, jet lag and the health impacts of shift work. This […]
Body clock pills ‘could cure jet lag and manic depression’
“A team of British and American scientists have found a drug which can slow down, kick start and reset the body clocks of mice. It does this by altering a key enzyme which controls the process, called casein kinase 1… He [Prof Loudon] and Dr Mick Hastings of the Medical Research Council Laboratory of Molecular […]