Release notes: Difference between revisions

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== Release 1.4 (September 2015) ==
== Release 1.4 (September 2015) ==
The main new features are:


# Full classification and auto-refine capabilities for sub-tomogram averaging ([http://dx.doi.org/10.1016/j.str.2015.06.026 Bharat et al, Structure 2015])  
# Full classification and auto-refine capabilities for sub-tomogram averaging ([http://dx.doi.org/10.1016/j.str.2015.06.026 Bharat et al, Structure 2015])  
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== Release 1.3 (June 2014) ==
== Release 1.3 (June 2014) ==
This release is a big step in the evolution of RELION from a stand-alone refinement program into a convenient pipeline for most of the single-particle analysis. It's main new features are:


# a movie-processing procedure for small (sub-Megadalton) particles ([http://dx.doi.org/10.7554/eLife.03665 Scheres, eLife 2014])
# a movie-processing procedure for small (sub-Megadalton) particles ([http://dx.doi.org/10.7554/eLife.03665 Scheres, eLife 2014])
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== Release 1.2 (June 2013) ==
== Release 1.2 (June 2013) ==
Apart from bug fixes and code optimisation, release 1.2 has two new main features:


# a statistical movie-processing procedure ([http://dx.doi.org/10.7554/eLife.00461 Bai et al, eLife 2013])
# a statistical movie-processing procedure ([http://dx.doi.org/10.7554/eLife.00461 Bai et al, eLife 2013])
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== Release 1.1 (September 2012) ==
== Release 1.1 (September 2012) ==


This release complements existing 2D and 3D procedures with:
# convenient preprocessing procedures
# convenient preprocessing procedures
# a fully automated refinement procedure (3D auto-refine) for homogeneous data sets, employing "gold-standard" FSC calculations ([http://dx.doi.org/10.1038/nmeth.2115 Scheres&Chen, Nat. Methods 2012], [http://dx.doi.org/10.1016/j.jsb.2012.09.006 Scheres, J. Struct. Biol. 2012])
# a fully automated refinement procedure (3D auto-refine) for homogeneous data sets, employing "gold-standard" FSC calculations ([http://dx.doi.org/10.1038/nmeth.2115 Scheres&Chen, Nat. Methods 2012], [http://dx.doi.org/10.1016/j.jsb.2012.09.006 Scheres, J. Struct. Biol. 2012])
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== Release 1.0 (November 2011) ==
== Release 1.0 (November 2011) ==


It all started with:
# 2D and 3D classification procedures. The latter can also be used for high-resolution refinement ([http://dx.doi.org/10.1016/j.jmb.2011.11.010 Scheres, J. Mol. Biol. 2012])
# 2D and 3D classification procedures. The latter can also be used for high-resolution refinement ([http://dx.doi.org/10.1016/j.jmb.2011.11.010 Scheres, J. Mol. Biol. 2012])

Revision as of 09:41, 28 August 2015

Release 1.4 (September 2015)

  1. Full classification and auto-refine capabilities for sub-tomogram averaging (Bharat et al, Structure 2015)
  2. 10x faster movie processing
  3. Much improved efficiency when running more than 4-6 threads.

Release 1.3 (June 2014)

  1. a movie-processing procedure for small (sub-Megadalton) particles (Scheres, eLife 2014)
  2. a template-matching based (semi-)automated particle picking procedure (Scheres, J. Struct. Biol. 2015)
  3. a new GUI with image-displaying functionalities. Just click your way through the entire image processing pipeline.

Release 1.2 (June 2013)

  1. a statistical movie-processing procedure (Bai et al, eLife 2013)
  2. a semi-automated post-processing procedure (for improved resolution estimates after masking, MTF correction and B-factor sharpening; Chen et al, Ultramicroscopy 2013 )

Release 1.1 (September 2012)

  1. convenient preprocessing procedures
  2. a fully automated refinement procedure (3D auto-refine) for homogeneous data sets, employing "gold-standard" FSC calculations (Scheres&Chen, Nat. Methods 2012, Scheres, J. Struct. Biol. 2012)

Release 1.0 (November 2011)

  1. 2D and 3D classification procedures. The latter can also be used for high-resolution refinement (Scheres, J. Mol. Biol. 2012)