This list denotes the numbers of functional VH, VK, VL, D, JH, JK and JL segments that belong to their respective V gene families. Please note that some individuals have polymorphic deletions of functional segments (or segments with open reading frames which are not rearranged) or have allelic differences which render certain segments non-functional. In these cases certain figures will be reduced. The numbers in these tables should therefore be regarded as the known maximum number of functional segments.

The Human Immunoglobulin Heavy Chain Repertoire (14q32.3) VH1 VH2 VH3 VH4 VH5 VH6 VH7 Total --------------------------------------------------------------------------------------- Functional 11 3 22 11 2 1 1 51 Non-rearranged ORF 1 0 6 0 1 0 1 9 --------------------------------------------------------------------------------------- D1 D2 D3 D4 D5 D6 D7 Total -------------------------------------------------------------------------------------- Functional 4 4 5 4 4 3 1 25 Non-rearranged ORF 1 0 0 0 0 1 0 2 -------------------------------------------------------------------------------------- JH1 JH2 JH3 JH4 JH5 JH6 Total ------------------------------------------------------------------------------ Functional 1 1 1 1 1 1 6 ------------------------------------------------------------------------------

The Human Immunoglobulin Kappa Chain Repertoire (2p11-12) VKI VKII VKIII VKIV VKV VKVI VKVII Total -------------------------------------------------------------------------------------- Functional 19 9 7 1 1 3 0 40 Non-rearranged ORF 3 4 1 0 0 0 1 9 -------------------------------------------------------------------------------------- JK1 JK2 JK3 JK4 JK5 Total ---------------------------------------------------------------------- Functional 1 1 1 1 1 5 ----------------------------------------------------------------------

The Human Immunoglobulin Lambda Chain Repertoire (22q11.2) VL1 VL2 VL3 VL4 VL5 VL6 VL7 VL8 VL9 VL10 Total --------------------------------------------------------------------------------------------------------------- Functional 5 5 9 3 3 1 2 1 1 1 31 Non-rearranged ORF 2 1 2 0 3 0 0 0 0 0 8 --------------------------------------------------------------------------------------------------------------- JL1 JL2 JL3 JL4 JL5 JL6 JL7 Total -------------------------------------------------------------------------------------- Functional 1 1 1 0 0 0 1 4 Non-rearranged ORF 0 0 0 1 1 1 0 3 --------------------------------------------------------------------------------------