Abnormal filamentous inclusions characterize many human neurodegenerative diseases, including Alzheimer’s and Parkinson’s. The formation of filaments or their mere presence is believed to result in the propagation of inclusions and neurodegeneration. Our work showed that the intracellular filaments of these diseases are made of either tau or alpha-synuclein. Others established that the extracellular deposits of … Continue reading Michel Goedert