Applications for the LMB PhD programme are now open. Deadline 3rd December 2024.
About Us
The MRC Laboratory of Molecular Biology (LMB) is a research institute dedicated to the understanding of important biological processes at the levels of atoms, molecules, cells and organisms. In doing so, we provide knowledge needed to solve key problems in human health.
Our scientists tackle fundamental, often difficult and long-term research problems. The LMB has made revolutionary contributions to science, such as pioneering X-ray crystallography and electron cryo-microscopy (cryo-EM) to determine protein structures, the sequencing of DNA and the development of monoclonal antibodies. Twelve Nobel Prizes have been awarded for work carried out by LMB scientists.
The LMB also promotes the application and exploitation of our research findings, both by collaboration with existing companies and the founding of new ones, helping to advance medical research and the translation and application of knowledge.
The LMB provides an unsurpassed environment for both young and established researchers, with state-of-the-art facilities and a unique scientific culture. The LMB has always been very diverse, with a truly international outlook. We currently employ men and women from over 50 countries, and LMB alumni work in research organisations across the world.
Insight on Research
Whole brain connectome of fruit fly is most complex brain ever mapped
An international collaboration, including Greg Jefferis’ group in the LMB’s Neurobiology Division, have published the connectome of the Drosophila fly – the most complex brain to be mapped in its entirety, including 140,000 neurons and over 15 million connections.
Using ultrasound to determine pregnancy in mice
Introduction of ultrasound machines has allowed LMB animal technicians to accurately detect pregnancy in mice as early as 5.5 days, which ultimately reduces the number of mice needed for research.
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Latest News
- Jason Chin receives honorary doctorate from ETH Zurich
Jason Chin, joint Head of the PNAC Division at the LMB, has been awarded an honorary doctorate by the ETH Zurich. […]
- Andrew Beale: a personal perspective of engaging the public
Andrew Beale shares his experiences of public engagement, reflecting on the diverse ways to connect with audiences, and encourages others to explore this important aspect of a research career. […]
Latest Publications
- VPS26 Moonlights as a β-Arrestin-like Adapter for a 7-Transmembrane RGS Protein in .
Lou, F., Zhou, W., Tunc-Ozdemir, M., Yang, J., Velazhahan, V., Tate, CG., Jones, AM.
Biochemistry 63(22): 2990-2999. (19th November 2024) - Soluble αβ-tubulins reversibly sequester TTC5 to regulate tubulin mRNA decay.
Batiuk, A., et al.
Nat Commun 15(1): 9963. (17th November 2024) - An image processing pipeline for electron cryo-tomography in RELION-5.
Burt, A., et al.
FEBS Open Bio 14(11): 1788-1804. (15th November 2024) - Gatekeepers of the brain: Identifying hidden mechanisms of type A GABA receptor signaling and assembly.
Sente, A.
Science 386(6723): 738-739. (15th November 2024) - The validation of an LC-MS/MS method for the quantification of vitamin D metabolites in human milk and their biological variability in Gambian women.
Jones, KS., Meadows, SR., Billing, G., Koulman, A., Prentice, A.
J Steroid Biochem Mol Biol 245: 106633 [Epub ahead of print]. (14th November 2024) - Virion morphology and on-virus spike protein structures of diverse SARS-CoV-2 variants.
Ke, Z., et al.
EMBO J [Epub ahead of print]. (14th November 2024) - Building a molecular reference map of the human embryo.
Sakata, RC., Shahbazi, MN.
Nat Methods [Epub ahead of print]. (14th November 2024)
See more Publications