About Us
The MRC Laboratory of Molecular Biology (LMB) is a research institute dedicated to the understanding of important biological processes at the levels of atoms, molecules, cells and organisms. In doing so, we provide knowledge needed to solve key problems in human health.
Our scientists tackle fundamental, often difficult and long-term research problems. The LMB has made revolutionary contributions to science, such as pioneering X-ray crystallography and electron cryo-microscopy (cryo-EM) to determine protein structures, the sequencing of DNA and the development of monoclonal antibodies. Twelve Nobel Prizes have been awarded for work carried out by LMB scientists.
The LMB also promotes the application and exploitation of our research findings, both by collaboration with existing companies and the founding of new ones, helping to advance medical research and the translation and application of knowledge.
The LMB provides an unsurpassed environment for both young and established researchers, with state-of-the-art facilities and a unique scientific culture. The LMB has always been very diverse, with a truly international outlook. We currently employ men and women from over 50 countries, and LMB alumni work in research organisations across the world.
Insight on Research
Motion detector in the brain translates visual information into movement
![](https://www2.mrc-lmb.cam.ac.uk/wordpress/wp-content/uploads/Tripodi_Nature_InsightOnResearch_AGR_Sq_07.2024-1-150x150.jpg)
Marco Tripodi’s group, in the LMB’s Neurobiology Division, reveals how visual information is progressively channelled to motor neurons.
Transcription factor Mef2d is crucial to the function of type-2 innate lymphoid cells during allergic responses
![](https://www2.mrc-lmb.cam.ac.uk/wordpress/wp-content/uploads/McKenzie_Szeto_Science_Mef2d_06.2024_sq-150x150.jpg)
Andrew McKenzie’s group, in the LMB’s PNAC Division, have applied a new screening system and synthetic Boolean logic gate circuits to offer unprecedented insights into the molecular regulation of type-2 innate lymphoid cells, a key contributor to allergic responses.
Quick Links
Latest News
Kiarash Jamali and David Posner receive Ph.D. Student Awards from Cambridge Society for the Application of Research
Congratulations to Ph.D. students Kiarash Jamali and David Posner who have received Ph.D. Student Awards from CSAR. […]
Lalita Ramakrishnan awarded 2024 Robert Koch Prize
Lalita Ramakrishnan, Group Leader in the LMB’s Cell Biology Division and the Molecular Immunity Unit, receives the award in recognition of her pioneering research into tuberculosis. […]
Latest Publications
- Data-driven regularization lowers the size barrier of cryo-EM structure determination.
Kimanius, D., Jamali, K., Wilkinson, ME., Lövestam, S., Velazhahan, V., Nakane, T., Scheres, SHW.
Nat Methods 21(7): 1216-1221. (11th July 2024) - β-H-Spectrin is a key component of an apical-medial hub of proteins during cell wedging in tube morphogenesis.
Gillard, G., Röper, K.
J Cell Sci [Epub ahead of print]. (11th July 2024) - Establishing African genomics and bioinformatics programs through annual regional workshops.
Sharaf, A., et al.
Nat Genet [Epub ahead of print]. (8th July 2024) - Evolution and host-specific adaptation of .
Weimann, A., et al.
Science 385(6704): eadi0908. (5th July 2024) - LarvaTagger: Manual and automatic tagging of drosophila larval behaviour.
Laurent, F., et al.
Bioinformatics [Epub ahead of print]. (5th July 2024) - Prebiotic synthesis of dihydrouridine by photoreduction of uridine in formamide.
Xu, J., Janicki, MJ., Szabla, R., Sutherland, JD.
Chem Commun (Camb) 60(55): 7081-7084. (4th July 2024) - Kinetic features dictate sensorimotor alignment in the superior colliculus.
González-Rueda, A., et al.
Nature 631(8020): 378-385. (3rd July 2024)
See more Publications