Scientific Seminars


Below is a list of upcoming seminars at the LMB aimed at a general scientific audience and open to individuals throughout Cambridge. If you are not at the LMB and wish to attend a seminar, please contact the seminar secretary.

The LMB hosts ‘The LMB Seminar Series’, where 1-2 leading scientists per month are invited to speak throughout the year. Four of these lectures are named in honour of LMB Nobel Laureates Max Perutz, Francis Crick, César Milstein and John Kendrew, given by eminent scientists from around the world. The LMB Seminar talks and LMB Named Seminar talks are advertised widely throughout the local area and are open to all.

2019 LMB Seminar Series speakers (click to expand)

  • Anne Ferguson Smith – 11am, 30th January
  • Meri Huch – 4pm, 28th February
  • Pietro Di Camilli – 4pm, 5th March
  • Janet Iwasa – Time TBC, 8th March
  • Lalita Ramakrishnan – Time TBC, 5th April
  • Gia Voeltz – Time TBC, 10th April
  • David Rudner – Time TBC, 3rd May
  • Tim Hubbard -Time TBC, 23rd May
  • Lily Jan – Time TBC, 19th September

 

A full list of LMB Named Lectures to date can be found here.

Details of other local seminars can be found here

  • Structures and transitions of the serotonin 5-HT3 receptor

    Speaker: Hugues Nury, Institut de Biologie Structurale, Grenoble, France
    Host: Radu Aricescu
    Date: 11/12/2018 at 4:00pm in the Sanger Seminar Room, Level 3, LMB.

    Further information

    The serotonin 5-HT3 receptor is a pentameric ligand-gated ion channel. It belongs to a large family of receptors that transduce signals across the plasma membrane. Upon binding of neurotransmitter molecules to extracellular sites, the receptors undergo complex conformational transitions, which result in transient opening of a pore permeable to ions. 5-HT3 receptors are therapeutic targets for emesis, irritable bowel syndrome and depression. I will present structures of the 5-HT3 receptor obtained by crystallography or cryo-electron microscopy. The structures, obtained in complex with inhibitors or agonists, represent snapshots in different states: inhibited, pre-active, active. Together with molecular dynamics simulations and functional recordings, they reveal the molecular mechanism of the fast neurotransmission mediated by 5HT3 receptors.