MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Scientific Seminars

Below is a list of upcoming seminars at the LMB aimed at a general scientific audience and open to individuals throughout Cambridge. If you are not at the LMB and wish to attend a seminar, please contact the seminar secretary, unless the seminar is held online and joining information is included in the seminar information below. The LMB hosts ‘The LMB Seminar Series’, where 1-2 leading scientists per month are invited to speak throughout the year. Four of these lectures are named in honour of LMB Nobel Laureates Max Perutz, Francis Crick, César Milstein and John Kendrew, given by eminent scientists from around the world. The LMB Seminar talks and LMB Named Seminar talks are advertised widely throughout the local area and are open to all.

A full list of LMB Named Lectures to date can be found here. Details of other local seminars can be found here

  • 3Rs Seminar Series: Replication, Repair and Recombination

    Speaker: Dr.Pierre Murat (MRC), Associate Prof. Martijn Luijsterburg (Leiden University Medical Center, Leiden)
    Host: Ross Hill
    Date: 11/05/2021 at 2:00pm in the Webinar.

    Further information

    Zoom link
    https://zoom.us/j/94071892336

    “Mechanisms in transcription-coupled
    DNA repair”
    Keynote: Associate Prof. Martijn Luijsterburg
    (Leiden University Medical Center, Leiden)

    “Mutagenesis at replication origins drives
    genetic and phenotypic diversity in
    human populations”
    Dr. Pierre Murat (MRC LMB, Cambridge)

    For more information: https://www2.mrc-lmb.cam.ac.uk/3RS/
    Or contact: Ross Hill (rjhill@mrc-lmb.cam.ac.uk)
    Chris Carnie (cjc225@cam.ac.uk)

  • LMB Seminar: Systemic regulation of brain aging and function

    Speaker: Tony Wyss-Coray, D. H. Chen Professor II, Stanford University, USA
    Host: Ben Falcon
    Date: 25/05/2021 at 4:00pm in the Webinar.

    Further information

    Zoom link: https://zoom.us/j/91691820397?pwd=aUNFUFFib1V5S2V4RUswRmlhN0pRQT09

    Brain aging leads to cognitive decline and is the main risk factor for sporadic forms of neurodegenerative diseases including Alzheimer’s disease. While brain cell- and tissue-intrinsic factors are likely key determinants of the aging process recent studies document a remarkable susceptibility of the brain to circulatory factors. Thus, blood borne factors from young mice or humans are sufficient to slow aspects of brain aging and improve cognitive function in old mice and, vice versa, factors from old mice are detrimental for young mice and impair cognition. In trying to understand the molecular basis of these observations we found evidence that the cerebrovasculature is an important target and that brain endothelial cells show prominent age-related transcriptional changes in response to plasma. We discovered that plasma proteins are taken up broadly into brain endothelial cells and that this process various greatly between individual cells and with aging. We are exploring the relevance of these findings for neurodegeneration and potential application towards therapies.