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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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    • Achievements
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        • 2018 – Greg Winter
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Recent Posts:

  • Celebrating the success of the LMB’s inaugural Technician Week
  • LMB receives silver LEAF accreditation for sustainable laboratory practices
  • Samantha Skehel 1967-2024
  • New insights into genetic mechanisms involved in kidney development
  • Technicians David Street and Andy Mace achieve Professional Registration
  • Phosphatase study solves substrate recruitment puzzle
  • Science in Action – accelerated evolution
  • Nagai-Oubridge Memorial Symposium
  • Tanmay Bharat named Blavatnik Award finalist for emerging scientific talent
  • Alzheimer’s disease and chronic traumatic encephalopathy tau filament assembly intermediates revealed by cryo-EM
  • The LMB raises over £1600 for North West Anglia Hospitals’ Charity
  • Sought FUS, Found TAF—A New Fibril in Frontotemporal Dementia
  • Celebrating Michel Goedert’s four decades at the LMB
  • The band and the rhythm
  • Molecular mechanics of mitotic error correction revealed by cryo-EM
  • Cheaper microscope could bring protein mapping technique to the masses
  • Discovery of a new amyloid-forming protein in neurodegenerative disease
  • A success for the Raymond Nicolet Trust charity cake sale at the LMB
  • Bart Barrell (1944-2023)
  • Low energy cryo-EM to widen accessibility for fast and accurate structure determination
  • 2023 Crick Lecture to be given by Jill Banfield 
  • Tracking the milestones of the genome sequencing revolution highlights LMB achievements
  • 2023 Perutz Lecture to be given by Paola Picotti
  • The Infinite Monkey Cage asks if octopuses are aliens on Earth
  • First map of wireless communication in the nervous system 
  • A new collection of Royal Society Biographical Memoirs highlights LMB’s scientists 
  • 60 years of the Colworth Medal highlights LMB success
  • How did organelles evolve within complex cells?
  • LMB gets hands-on with a pipetting challenge at the Big Biology Day
  • Benjamin Ryskeldi-Falcon awarded the 2023 SCOR Young European Researcher Prize
  • Sarah Teichmann elected as Professor in Stem Cell Medicine at the Cambridge Stem Cell Institute
  • William Batey’s apprenticeship experience in the LMB’s Estates and Facilities Department
  • 2023 John Kendrew Lecture to be given by Wolfgang Baumeister
  • Perutz, Steitz and Southgate Prizes awarded to LMB students, postdocs and staff
  • LMB cycles to success in September challenge
  • Annette Faux (1966-2023)
  • New mechanism found that maintains intracellular water balance
  • Celebrating Neil Grant’s 40 years of service at the LMB
  • New deep screening technique enables rapid discovery of high-affinity antibodies to clinically relevant drug targets
  • Greg Jefferis appointed as Joint Head of the LMB’s Neurobiology Division
  • Michel Goedert and Sjors Scheres receive a 2023 Annemarie Opprecht Parkinson Award
  • New method to untangle the contribution of signalling pathways involved in asymmetric cell division
  • Stanislau Yatskevich wins the Birnstiel Award
  • Catarina Franco appointed Head of Mass Spectrometry
  • Daniela Rhodes receives the 2023 WLA Prize in Life Science or Medicine
  • First Cryo-EM structures of homomeric GluA1 AMPA glutamate receptor reveals functional roles for N-terminal domains
  • Radu Aricescu awarded the Karolinska Institutet 2023 Ulf von Euler Lectureship
  • Activation of the integrated stress response by inhibitors of its kinases
  • The LMB welcomes Juliette Fedry as a new Group Leader
  • Andrew McLachlan. 25 January 1935 – 8 July 2022
  • Madeline Lancaster awarded the Cheryll Tickle Medal from the British Society for Developmental Biology
  • Herman Waldmann awarded 2023 Royal Medal from the Royal Society
  • Joe Greener appointed Group Leader in the LMB’s Structural Studies Division
  • Connecting the microscopic world to children’s everyday lives
  • Cryo-EM structures reveal the unexpected ability of shelterin to modulate telomeric nucleosomes
  • Chevron shape of TDP-43 in FTLD points to distinct arrangements of TDP-43 as distinguishing feature between neurodegenerative diseases
  • The ‘Unknome’ genes which make up a fifth of the human genome
  • Repurposed DNA repair factors prevent expansions of ‘parasitic’ genomic retrotransposons
  • Muriel Wigby 1932 – 2023
  • LMB staff share their creative side at the Arts and Crafts Show
  • A database to identify important genes of unknown function for analysis
  • TDP-43 forms amyloid filaments with distinct folds in different neurodegenerative conditions
  • LMB welcomes over 2500 visitors to an action-packed Open Day
  • New insights into how DNA synthesis is started during the process of chromosome replication
  • The Chin group unveils gene synthesis breakthrough
  • Keeping protein subunits in check via assembly quality control 
  • LMB alumnae return to share their career stories at the fourteenth LMB-Cambridge AWiSE event
  • Great British Railway Journeys visits LMB to learn about the significance of the discovery of the structure of DNA
  • New pathway for cells to detect bacterial infection
  • Katja Röper elected to EMBO membership
  • Sarah Cumbers appointed chief executive of Royal Statistical Society
  • Pore-forming protein perforin-2 is critical to immune response by dendritic cells
  • Stephen Wallace wins Norman Heatley Award from Royal Society of Chemistry
  • Antiviral Bicycles are effective against SARS-CoV-2
  • Neuroprotective protein ADNP is vital to immune reactions to allergens
  • Secretary of State visits the LMB 
  • Julian Rayner elected Fellow of the Academy of Medical Sciences
  • How flies use smell to determine the identity and position of other flies
  • Activating the kinase protein PI3Kα revealed as a potential therapeutic target to protect and regenerate cells
  • Lori Passmore on her research career so far, the benefits of collaboration, and her greatest achievement away from the lab
  • LMB Alumni elected to US National Academy of Sciences
  • Andrew Carter on dynein discoveries, his career so far, and pursuits away from research
  • Lori Passmore elected Fellow of Royal Society
  • LMB Lecture on John Kendrew’s personal and scientific life to be given by Paul Wassarman
  • Akaash Kumar receives PhD Student Award from Cambridge Society for the Application of Research
  • Understanding the protein modifications behind Trim-Away protein degradation technology
  • From fertilisation PhD studies to AI in healthcare: Hannah Webb’s policy internship at The Academy of Medical Sciences
  • The structure of the surface layer of the toughest bacterium known elucidated
  • Kelly Nguyen awarded Biochemical Society Colworth Medal
  • Shalini Arun Prasad: Head of Media Prep and Glasswash
  • Simon Elsässer receives the 2023 Svedberg Prize
  • LMB showcases the beauty of the microscopic world at the Cambridge Festival
  • Lalita Ramakrishnan’s approach to tuberculosis research
  • Luka Smalinskaite is announced as the 2023 winner of British Society for Cell Biology’s Raff Medal
  • Complex map of fly brain reveals neurological insights
  • Apprenticeship success in the LMB workshops
  • Complete synaptic-resolution connectome of an insect larval brain
  • Matthew Freeman: The new Chair of EMBO Council
  • Aggregation of proteins on cell surface triggers rapid uptake and degradation
  • New computational method for genome analysis
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