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About Us

The MRC Laboratory of Molecular Biology (LMB) is a research institute dedicated to the understanding of important biological processes at the levels of atoms, molecules, cells and organisms. In doing so, we provide knowledge needed to solve key problems in human health.

Our scientists tackle fundamental, often difficult and long-term research problems. The LMB has made revolutionary contributions to science, such as pioneering X-ray crystallography and electron cryo-microscopy (cryo-EM) to determine protein structures, the sequencing of DNA and the development of monoclonal antibodies. Twelve Nobel Prizes have been awarded for work carried out by LMB scientists.

The LMB also promotes the application and exploitation of our research findings, both by collaboration with existing companies and the founding of new ones, helping to advance medical research and the translation and application of knowledge.

The LMB provides an unsurpassed environment for both young and established researchers, with state-of-the-art facilities and a unique scientific culture. The LMB has always been very diverse, with a truly international outlook. We currently employ men and women from over 50 countries, and LMB alumni work in research organisations across the world.

Insight on Research

New insights into the architecture of organelle contact sites, and the sites’ roles in cellular lipid fluxes

Live fluorescence microscopy of two fluorescently labeled proteins involved in the formation of contact sites

Correlative microscopy, in situ imaging of protein organisation and yeast genetics refine our understanding of ER-plasma membrane contact sites

New understanding of protein abundance control

Translating ribosomes with the emerging protein acting as a beacon

Translating ribosomes display a beacon that is exploited for selective mRNA degradation

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Latest Publications

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