Applications for the LMB PhD programme are now open. Deadline 3rd December 2024.
About Us
The MRC Laboratory of Molecular Biology (LMB) is a research institute dedicated to the understanding of important biological processes at the levels of atoms, molecules, cells and organisms. In doing so, we provide knowledge needed to solve key problems in human health.
Our scientists tackle fundamental, often difficult and long-term research problems. The LMB has made revolutionary contributions to science, such as pioneering X-ray crystallography and electron cryo-microscopy (cryo-EM) to determine protein structures, the sequencing of DNA and the development of monoclonal antibodies. Twelve Nobel Prizes have been awarded for work carried out by LMB scientists.
The LMB also promotes the application and exploitation of our research findings, both by collaboration with existing companies and the founding of new ones, helping to advance medical research and the translation and application of knowledge.
The LMB provides an unsurpassed environment for both young and established researchers, with state-of-the-art facilities and a unique scientific culture. The LMB has always been very diverse, with a truly international outlook. We currently employ men and women from over 50 countries, and LMB alumni work in research organisations across the world.
Insight on Research
Whole brain connectome of fruit fly is most complex brain ever mapped
An international collaboration, including Greg Jefferis’ group in the LMB’s Neurobiology Division, have published the connectome of the Drosophila fly – the most complex brain to be mapped in its entirety, including 140,000 neurons and over 15 million connections.
Using ultrasound to determine pregnancy in mice
Introduction of ultrasound machines has allowed LMB animal technicians to accurately detect pregnancy in mice as early as 5.5 days, which ultimately reduces the number of mice needed for research.
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Latest News
- Liqun Luo to deliver 2024 Kendrew Lecture
The 2024 John Kendrew Lecture titled ‘Wiring specificity of neural circuits’ will be given by Liqun Luo at 11am (GMT) on Monday 4th November. […]
- Akaash Kumar awarded Early Career Award from Royal Microscopical Society
Congratulations to Akaash Kumar, who’s Ph.D. work developing a novel microscopic imaging system has been recognised with the Royal Microscopical Society’s Early Career Award. […]
Latest Publications
- EMhub: a web platform for data management and on-the-fly processing in scientific facilities.
de la Rosa-Trevin, JM., et al.
Acta Crystallogr D Struct Biol [Epub ahead of print]. (1st November 2024) - Systemic and local lipid adaptations underlie regeneration in Drosophila melanogaster and Ambystoma mexicanum.
Kübler, IC., et al.
NPJ Regen Med 9(1): 33. (29th October 2024) - RNA-directed peptide synthesis across a nicked loop.
Su, M., Roberts, SJ., Sutherland, JD.
Nucleic Acids Res 52(19): 11415-11422. (28th October 2024) - VPS26 Moonlights as a β-Arrestin-like Adapter for a 7-Transmembrane RGS Protein in .
Lou, F., Zhou, W., Tunc-Ozdemir, M., Yang, J., Velazhahan, V., Tate, CG., Jones, AM.
Biochemistry [Epub ahead of print]. (28th October 2024) - Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 function.
Swamynathan, MM., et al.
Science 386(6720): eadk9167. (25th October 2024) - Antibodies targeting the Crimean-Congo Hemorrhagic Fever Virus nucleoprotein protect via TRIM21.
Leventhal, SS., et al.
Nat Commun 15(1): 9236. (25th October 2024) - Constitutive sodium permeability in a two-pore domain potassium channel.
Andrini, O., et al.
Proc Natl Acad Sci U S A 121(43): e2400650121. (22nd October 2024)
See more Publications