The MRC Laboratory of Molecular Biology (LMB) is a research institute dedicated to the understanding of important biological processes at the levels of atoms, molecules, cells and organisms. In doing so, we provide knowledge needed to solve key problems in human health.
Our scientists tackle fundamental, often difficult and long-term research problems. The LMB has made revolutionary contributions to science, such as pioneering X-ray crystallography to determine protein structures, the sequencing of DNA and the development of monoclonal antibodies. Eleven Nobel Prizes have been awarded for work carried out by LMB scientists.
The LMB also promotes the application and exploitation of our research findings, both by collaboration with existing companies and the founding of new ones, helping to advance medical research and the translation and application of knowledge.
The LMB provides an unsurpassed environment for both young and established researchers, with state-of-the-art facilities and a unique scientific culture. The LMB has always been very diverse, with a truly international outlook. We currently employ men and women from over 50 countries, and LMB alumni work in research organisations across the world.
In our day-to-day lives we execute spatially targeted movements with ease and seemingly without much thought. These movements may include reaching for your morning cup of coffee, checking your mirrors on your drive into work, or catching a cricket ball. On the…
Scientists in Philipp Holliger’s group in the LMB’s PNAC Division have created a new type of genetic replication system to demonstrate how the first life on Earth – in the form of RNA – could have replicated itself. Our understanding of life’s…
- Melina Schuh awarded the EMBO Gold Medal
Melina Schuh, at the Max Planck Institute for Biophysical Chemistry and former group leader in […]
- Lori Passmore and Felix Randow elected to EMBO membership
Lori Passmore, group leader in the LMB’s Structural Studies Division, and Felix Randow, group leader […]
- A new synthetic molecule may solve a paradox about life’s origin
- How to be better at networking at conferences
- Combining fluorescence imaging with Hi-C to study 3D genome architecture of the same single cell.
Lando, D., et al.
Nat Protoc 13(5): 1034-1061. (19th May 2018)
- Sensory-Neuropathy-Causing Mutations in ATL3 Cause Aberrant ER Membrane Tethering.
Krols, M., et al.
Cell Rep 23(7): 2026-2038. (15th May 2018)
- Ribozyme-catalysed RNA synthesis using triplet building blocks.
Attwater, J., Raguram, A., Morgunov, AS., Gianni, E., Holliger, P.
Elife 7 [Epub ahead of print]. (15th May 2018)
- Photochemical reductive homologation of hydrogen cyanide using sulfite and ferrocyanide.
Xu, J., Ritson, DJ., Ranjan, S., Todd, ZR., Sasselov, DD., Sutherland, JD.
Chem. Commun. (Camb.) [Epub ahead of print]. (15th May 2018)
- High-throughput discovery of functional disordered regions: investigation of transactivation domains.
Ravarani, CN., Erkina, TY., De Baets, G., Dudman, DC., Erkine, AM., Babu, MM.
Mol. Syst. Biol. 14(5): e8190. (14th May 2018)
- Pathway perturbations in signaling networks: Linking genotype to phenotype.
Li, Y., McGrail, DJ., Latysheva, N., Yi, S., Babu, MM., Sahni, N.
Semin. Cell Dev. Biol. [Epub ahead of print]. (10th May 2018)
- Brain organoids get vascularized.
Nat. Biotechnol. 36(5): 407-408. (9th May 2018)
See more Publications