In line with government instructions, the LMB buildings opened further from Monday 6 July to enable all general lab work, while those that can work from home continue to do so. The LMB COVID-19 risk assessment has been updated and measures are in place to manage the risk from infection including strict social distancing measures in all areas of the building and maintaining high standards of both personal and environmental hygiene, including face masks in most areas.
All internal and external meetings continue to be held via video or teleconferencing. Please use email as the preferred means of contacting members of LMB.
COVID-19 research remains active at LMB, with over 12 separate strands of research into various aspects of the SARS-CoV-2 virus underway:
The MRC Laboratory of Molecular Biology (LMB) is a research institute dedicated to the understanding of important biological processes at the levels of atoms, molecules, cells and organisms. In doing so, we provide knowledge needed to solve key problems in human health.
Our scientists tackle fundamental, often difficult and long-term research problems. The LMB has made revolutionary contributions to science, such as pioneering X-ray crystallography and electron cryo-microscopy (cryo-EM) to determine protein structures, the sequencing of DNA and the development of monoclonal antibodies. Twelve Nobel Prizes have been awarded for work carried out by LMB scientists.
The LMB also promotes the application and exploitation of our research findings, both by collaboration with existing companies and the founding of new ones, helping to advance medical research and the translation and application of knowledge.
The LMB provides an unsurpassed environment for both young and established researchers, with state-of-the-art facilities and a unique scientific culture. The LMB has always been very diverse, with a truly international outlook. We currently employ men and women from over 50 countries, and LMB alumni work in research organisations across the world.
Lipid membranes surround our cells and form the boundaries around compartments within them. Roger Williams’ group has now shown how membrane characteristics can tune the activities of protein complexes with important roles in autophagy and endosomal membrane trafficking.
Producing maps of how neurons connect with each other (connectomes) allows scientists to build and test theories of brain function. Greg Jefferis’ group have presented the first full map of olfactory, thermosensory, and hygrosensory projection neurons in the fly brain.
- Alan Fersht and Marta Zlatic win Royal Society Medals
Alan Fersht has been awarded the Royal Society Copley Medal and Marta Zlatic receives the Francis Crick Medal, in recognition of their scientific achievements. […]
- The LMB welcomes Buzz Baum as a new Group Leader
Buzz Baum joins the LMB as a new Group Leader in the Cell Biology Division, where his group will continue their research into the evolution of cell division. […]
- USP30 sets a trigger threshold for PINK1-PARKIN amplification of mitochondrial ubiquitylation.
Rusilowicz-Jones, EV., et al.
Life Sci Alliance 3(8). (7th August 2020)
- Opa1 Overexpression Protects from Early-Onset Mpv17-Related Mouse Kidney Disease.
Luna-Sanchez, M., et al.
Mol. Ther. 28(8): 1918-1930. (5th August 2020)
- Intracellular neutralisation of rotavirus by VP6-specific IgG.
Caddy, SL., et al.
PLoS Pathog. 16(8): e1008732 [Epub ahead of print]. (4th August 2020)
- ILC2-driven innate immune checkpoint mechanism antagonizes NK cell antimetastatic function in the lung.
Schuijs, MJ., et al.
Nat. Immunol. [Epub ahead of print]. (3rd August 2020)
- Characterising the binding and function of TARP γ8-selective AMPA receptor modulators.
Dohrke, JN., Watson, JF., Birchall, K., Greger, IH.
J. Biol. Chem. [Epub ahead of print]. (3rd August 2020)
- Identification and characterization of diverse OTU deubiquitinases in bacteria.
Schubert, AF., et al.
EMBO J. 39(15): e105127. (3rd August 2020)
- Brain Organoids: Human Neurodevelopment in a Dish.
Benito-Kwiecinski, S., Lancaster, MA.
Cold Spring Harb Perspect Biol 12(8). (3rd August 2020)
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