• Photo of the new LMB building opened in 2012

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About Us

The MRC Laboratory of Molecular Biology (LMB) is a research institute dedicated to the understanding of important biological processes at the levels of atoms, molecules, cells and organisms. In doing so, we provide knowledge needed to solve key problems in human health.

Our scientists tackle fundamental, often difficult and long-term research problems. The LMB has made revolutionary contributions to science, such as pioneering X-ray crystallography and electron cryo-microscopy (cryo-EM) to determine protein structures, the sequencing of DNA and the development of monoclonal antibodies. Twelve Nobel Prizes have been awarded for work carried out by LMB scientists.

The LMB also promotes the application and exploitation of our research findings, both by collaboration with existing companies and the founding of new ones, helping to advance medical research and the translation and application of knowledge.

The LMB provides an unsurpassed environment for both young and established researchers, with state-of-the-art facilities and a unique scientific culture. The LMB has always been very diverse, with a truly international outlook. We currently employ men and women from over 50 countries, and LMB alumni work in research organisations across the world.

Insight on Research

New insights into genetic mechanisms involved in kidney development

John-Poul Ng-Blichfeldt and Katja Röper, in the LMB’s Cell Biology Division, have collaborated with Julie Williams from AstraZeneca, to use renal organoids to investigate the human mesenchymal-to-epithelial transition, crucial to the morphogenesis of kidneys.

Phosphatase study solves substrate recruitment puzzle

Anne Bertolotti’s group in the LMB Neurobiology Division have revealed the substrate recruitment mechanism of major phosphatase non-catalytic subunit, PPP1R15B, by using full-length eIF2 and a combination of approaches.

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Latest Publications

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