• Photo of the new LMB building opened in 2012

In line with government instructions, the LMB buildings opened further from Monday 6 July to enable all general lab work, while those that can work from home continue to do so. The LMB COVID-19 risk assessment has been updated and measures are in place to manage the risk from infection including strict social distancing measures in all areas of the building and maintaining high standards of both personal and environmental hygiene, including face masks in most areas.

All internal and external meetings continue to be held via video or teleconferencing. Please use email as the preferred means of contacting members of LMB.

COVID-19 research remains active at LMB, with over 14 separate strands of research into various aspects of the SARS-CoV-2 virus underway:

How the LMB is fighting the COVID-19 pandemic

 

About Us

The MRC Laboratory of Molecular Biology (LMB) is a research institute dedicated to the understanding of important biological processes at the levels of atoms, molecules, cells and organisms. In doing so, we provide knowledge needed to solve key problems in human health.

Our scientists tackle fundamental, often difficult and long-term research problems. The LMB has made revolutionary contributions to science, such as pioneering X-ray crystallography and electron cryo-microscopy (cryo-EM) to determine protein structures, the sequencing of DNA and the development of monoclonal antibodies. Twelve Nobel Prizes have been awarded for work carried out by LMB scientists.

The LMB also promotes the application and exploitation of our research findings, both by collaboration with existing companies and the founding of new ones, helping to advance medical research and the translation and application of knowledge.

The LMB provides an unsurpassed environment for both young and established researchers, with state-of-the-art facilities and a unique scientific culture. The LMB has always been very diverse, with a truly international outlook. We currently employ men and women from over 50 countries, and LMB alumni work in research organisations across the world.

Insight on Research

First complete atomic model of condensin lays foundation for understanding chromosome compaction

Cryo-EM map of condensin

Each of our cells contains about two metres of DNA. To be able to store all of this, the DNA must be very tightly compacted. Jan Löwe’s group have produced the first atomic model of condensin, a complex known to have a role in compacting DNA into chromosomes, in its entirety.

Balancing an appropriate immune response in the gut

Menna Clatworthy’s group has identified a key signalling molecule in determining the balance between wound healing and defence against bacterial invasion, with implications for our understanding of the immune system’s role in inflammatory bowel disease.

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Latest Publications


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