About Us
The MRC Laboratory of Molecular Biology (LMB) is a research institute dedicated to the understanding of important biological processes at the levels of atoms, molecules, cells and organisms. In doing so, we provide knowledge needed to solve key problems in human health.
Our scientists tackle fundamental, often difficult and long-term research problems. The LMB has made revolutionary contributions to science, such as pioneering X-ray crystallography and electron cryo-microscopy (cryo-EM) to determine protein structures, the sequencing of DNA and the development of monoclonal antibodies. Twelve Nobel Prizes have been awarded for work carried out by LMB scientists.
The LMB also promotes the application and exploitation of our research findings, both by collaboration with existing companies and the founding of new ones, helping to advance medical research and the translation and application of knowledge.
The LMB provides an unsurpassed environment for both young and established researchers, with state-of-the-art facilities and a unique scientific culture. The LMB has always been very diverse, with a truly international outlook. We currently employ men and women from over 50 countries, and LMB alumni work in research organisations across the world.
Insight on Research
Revealing the hidden switch behind aggressive cancers

By capturing the first high-resolution structure of ADGRL4 in its active state, David Favara in Chris Tate’s group in the LMB’s Structural Studies Division has identified how a G-protein couples and revealed its activation method, paving the way for new cancer therapies.
Distinct AMPA receptor sub-types reside within glial and neuronal cells of the cerebellum

Multidisciplinary study from Ingo Greger’s group in the LMB’s Neurobiology Division reveals the structures and subunit assembly of GluA4 AMPA receptors in the mammalian cerebellum that support cell-type specific functions.
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Latest News
2026 Max Perutz Lecture to be given by Dirk GörlichThe 2026 Max Perutz Lecture titled ‘Transport through nuclear pores’ will be given by Dirk Görlich at 11am (GMT) on 19th January. […]
Neil Sands appointed Stores ManagerNeil Sands joined the LMB just over a year ago as the new Stores Manager, overseeing the inspection, receipting, handling, storage and distribution of all deliveries into the LMB. […]
Latest Publications
- Multifaceted B cell response to transient HIV viremia in elite controllers.
Muir, L., et al.
PLoS Pathog 22(1): e1013817 [Epub ahead of print]. (16th January 2026) - Genotype-stratified adjunctive dexamethasone for tuberculous meningitis in HIV-negative adults: a randomized controlled phase 3 trial.
Donovan, J., et al.
Nat Med [Epub ahead of print]. (15th January 2026) - Volumetric Single-Molecule Tracking Inside Subcellular Structures.
Daly, S., et al.
Small : e09162 [Epub ahead of print]. (15th January 2026) - Insights from aquaporin structures into drug-resistant sleeping sickness.
Matusevicius, M., et al.
Elife 14. (14th January 2026) - Adjusting PSC culture for neural organoid generation.
Sutcliffe, MA., Jensen, P., Tan, J., Morris, CAJ., Fazakerley, DJ., Larsen, MR., Lancaster, MA.
Stem Cell Reports 21(1): 102724. (13th January 2026) - The mechanism of cell-cycle-dependent proteasomal degradation of archaeal ESCRT-III homolog CdvB in Sulfolobus.
Kuo, YW., Traparić, J., Foo, S., Baum, B.
EMBO J [Epub ahead of print]. (9th January 2026) - Large-scale testing of antimicrobial lethality at single-cell resolution predicts mycobacterial infection outcomes.
Jovanovic, A., et al.
Nat Microbiol [Epub ahead of print]. (9th January 2026)
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