• Skip to primary navigation
  • Skip to main content
  • Skip to primary sidebar
MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

  • Home
  • About LMB
  • Research
  • Research Groups
  • Students
  • Recruitment
  • Life at the LMB
  • Achievements
  • News & Events

Public Engagement

Atomic advance for cryo-EM

Published on 21 October, 2020

Looking at the precise 3D arrangement of atoms within a protein helps us to understand how it can perform its functions. Radu Aricescu’s and Sjors Scheres’ groups have now been able to resolve individual atoms for the first time in a three-dimensional cryo-EM image.

Freezing molecules completely still for cryo-EM

Published on 9 October, 2020

Specimen movement reduces the quality of structural data produced by cryo-EM. Chris Russo’s group presents a physical theory for the causes of this movement, and creates a new specimen support that eliminates it.

Catching the ribosome in the act of scanning mRNA

Published on 4 September, 2020

Venki Ramakrishnan’s group has solved the structure of the protein complex formed when mRNA is being scanned to find the start codon, providing new understanding of the molecular mechanisms underpinning initiation of translation.

Studying the spike protein of SARS-CoV-2

Published on 18 August, 2020

John Briggs’ group has led two new studies of the spike (S) protein that mediates binding to the receptor ACE2 and is the dominant target of the immune system, with applications for development of vaccines and diagnostic tests.

First structures of α-synuclein filaments from human brain

Published on 28 May, 2020

Abnormal filaments of α-synuclein define several neurodegenerative diseases, including multiple system atrophy (MSA) and Parkinson’s disease. Michel Goedert’s and Sjors Scheres’ groups have now determined the first structures of α-synuclein filaments from human brain.

Unravelling the replisome: how a molecular machine overcomes obstacles to DNA replication

Published on 4 May, 2020

Every time a cell divides, all of its genetic material must be accurately duplicated. This process is controlled by a molecular machine known as the replisome. Joseph Yeeles’ group has now produced the highest resolution, and most complete, structure of a replisome to date.

  • Go to page 1
  • Go to page 2
  • Go to Next Page »

Primary Sidebar

Search

  • Privacy & Cookies
  • Contact Directory
  • Freedom of Information
  • Site Map
Find Us
©2023 MRC Laboratory of Molecular Biology,
Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. 01223 267000

The MRC is part of UK Research and Innovation

Contact Us