Category Archives: Image365
Asymmetric cell division is the process by which one cell gives rise to two daughters that have different fate. Asymmetric cell division is the hallmark of stem cells, which generate all the different cell types in the organism. The Derivery Lab in the Cell Biology Division uses the fruit fly to study the molecular mechanism of asymmetric cell division as it is amenable to imaging and genetic modifications. This image for day 323 of #LMB365 represents the back of the fly (called the notum), where all the cells express a cytoskeleton marker in green, while only the cells dividing asymmetrically express a red marker. These cells form a remarkable aligned array, which will give rise to the mechanosensory bristles on the adult fly.
Day 322 of #LMB365 shows Li Jin and Christine Hilcenko setting up their stand at the LMB for a charity cake sale in support of The Raymond Nicolet Trust. The sale achieved an amazing £178 that will fully go to support educational establishments in Serbia.
If you have ever wondered how all the glass in the atrium of the LMB is kept clean, this photo for day 321 of #LMB365 shows you how. This is carried out biennially and takes two people 8 days to clean all the glass, including the fascia boards, high girders, tops of pods, and floodlights. Throughout the process care is taken to protect the atrium floor.
On day 320 of #LMB365 we have a picture by Katja Röper in the Cell Biology Division. This image shows a confocal image of the forming tube of the salivary glands in a Drosophila embryo, a model system for the formation of tubular organs. Tube cells are in green, and this forming tube is aberrant and forked due to a specific genetic mutation affecting tube formation. The Röper lab studies how important tubular organs from flies to humans form during development.
The Electronics Workshop stocks an impressive array of electronic components and ‘useful bits and pieces’ as seen here on day 319 of #LMB365. They come in especially useful when a visiting contractor is short of something to finish a job.
This photo for day 318 of #LMB365 was taken by Paul Margiotta from the nearby Green and Gardens public space showing the LMB in the background. The tent sculpture was designed by artist Ryan Gander and is one of several items in this new landscape and public art installation.
This image provided by David Barford for day 317 of #LMB365 shows the cryo-EM structure of the anaphase-promoting complex (APC/C) (surface representation) bound to its inhibitor, the mitotic checkpoint complex (MCC) (ribbons representation). The MCC exerts the spindle assembly checkpoint during mitosis to coordinate APC/C activity with the correct attachment of all chromosomes to the mitotic spindle. This ensures faithful chromosome segregation and prevents aneuploidy, a causative factor in cancer and congenital defects.
Fire safety is vitally important for the protection of our staff and facilities. This photo for day 316 of #LMB365 shows a recent hands-on staff training session on how, when and where to use fire extinguishers.
On day 315 of #LMB365 we see the PDB Art Exhibition, currently on display in the LMB’s atrium, in which students from local schools have produced amazing works of art inspired by protein structures. More close-ups to come…
It’s not every day a steam train goes past the LMB. Day 314 of #LMB365 shows the 61306 Mayflower on a recent trip from London. Mayflower is a B1 Class locomotive and was built in 1948 by the North British Locomotive Company in Glasgow for the London & North Eastern Railway