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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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LMB In The News

Lalita Ramakrishnan’s approach to tuberculosis research

Published on 24 March, 2023

To mark World TB Day, Lalita Ramakrishnan, Group Leader in the LMB’s Cell Biology Division and the University of Cambridge’s Molecular Immunity Unit (housed at the LMB), discusses her career journey, the inspiration behind many of her key tuberculosis findings, and her approach to mentoring in the lab. More…

Complex map of fly brain reveals neurological insights

Published on 16 March, 2023

Marta Zlatic and Albert Cardona’s groups in the LMB’s Neurobiology Division (also at the University of Cambridge) have unveiled the first complete map of a fruit fly brain, including all its neurons and connecting synapses. This connectome offers new insights into the brain and will serve as a reference brain, allowing researching to study neurological […]

Kate McDole on developing smart microscopes

Published on 15 February, 2023

Kate McDole, Group Leader in the LMB’s Cell Biology Division, discusses how she has developed an adaptive microscope to track cell movement in mice embryos, including design considerations to control factors including specimen movement, angle of light source and positions of optical elements. More…

Heartburn drug could be effective TB treatment

Published on 14 February, 2023

New research from Lalita Ramakrishnan’s group, in the LMB’s Cell Biology Division and the University of Cambridge’s Molecular Immunity Unit (housed at the LMB), has shown that drugs commonly used to treat heartburn could shorten treatment time of tuberculosis (TB), as well as reduce the likelihood of TB bacteria becoming drug resistant. More…

Gaucher disease may offer Ashkenazi Jews protection against TB

Published on 14 February, 2023

Lalita Ramakrishnan’s group, in the LMB’s Cell Biology Division and the University of Cambridge’s Molecular Immunity Unit (housed at the LMB) have discovered that the biological mechanisms which underpin Gaucher disease – a rare genetic disease which is most commonly found amongst Ashkenazi Jews – are also effective at clearing tuberculosis infection. More…

Enhanced understanding of how HIV-1 infect our cells

Published on 27 January, 2023

The Cambridge Independent reports on a study from Leo James’ group in the LMB’s PNAC Division which has identified the process whereby HIV-1 builds its capsid using the metabolite IP6 which is captured from cells with a net-like protein lattice. More…

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