The LMB recently welcomed George Freeman MP as part of a wider visit to the Cambridge Biomedical Campus to learn how Cambridge is leading innovation in life sciences. During a tour of the LMB with Jan Löwe, Chris Russo and Madeline Lancaster, the Minister saw and learned how developments in low-energy cryo-EM will increase accessibility […]
LMB In The News
Collaborative LMB study reveals S-shaped structure of Aβ42 filaments in Alzheimer’s disease and other neurodegenerative diseases
A recent structural study led by Sjors Scheres, Michel Goedert and Benjamin Ryskeldi-Falcon’s groups at the LMB has used cryo-EM to detect two main types of Aβ42 filaments from both sporadic and familial Alzheimer’s disease. More…
New research initiative at the University of Cambridge supports a cross-disciplinary approach to better understand life across the Universe
The University of Cambridge is establishing The Leverhulme Centre for Life in the Universe to support international and cross-disciplinary research on planetology and life beyond Earth. LMB scientist and Group Leader in PNAC, John Sutherland, is appointed Associate Director of the centre. John will be collaborating with global scientists, including Director and Nobel Prize winner, […]
In The Stem Cell Jungle explore how embryonic stem cell signalling drives cell fate
Marta Shahbazi discusses her lab’s work on the benefits of culturing embryonic stem cells in 3D to better understand how stem cell signalling drives cell fate. “I became very interested in how a stem cell decides its fate and really the best model to understand that is the embryo.” More…
Wasi Faruqi reminisces on his scientific career in Cambridge
Wasi Faruqi joined the LMB in 1969 where he has since remained as an integral contributor to the lab’s Structural Studies Division. In 2021 Wasi’s work on the development of electron microscopy was honoured by an MBE. Here Wasi reflects on his scientific career and his engagement with Clare Hall as a Life Member. More…
Double spiral structure is unique to TDP-43 filament behind ALS and FTD neurodegenerative diseases
A recent paper from Benjamin Ryskeldi-Falcon’s group reveals the first atomic structure of TDP-43 filaments from the brains of people with ALS and FTD diseases. The discovered structure possesses a unique double-spiral fold at its core, differentiating it from all other amyloidogenic proteins observed so far. More…