MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

Projects

Applications for October 2024 now open.
Deadline 5 December 2023.

David Barford

Cryo-EM study of the human kinetochore

Buzz Baum

How one archaeal cell becomes two

Anne Bertolotti

Boosting protein quality control

Simon Bullock

Shedding light on microtubule-based transport

Andrew Carter

Transport of cargos in the neuronal axon

Emmanuel Derivery

Illuminating the endosomal sorting pathway

Juliette Fedry

Visualizing cellular proteostasis

Joe Greener

Learning a universal biomolecular force field

Ingo Greger

AMPA receptor structure and function

Ramanujan Hegde

Protein maturation, quality control, and disease

Philipp Holliger

Replicating RNA with RNA

Gregory Jefferis

Neural Circuits for Sex and Memory in the Fly

Madeline Lancaster

How signals inside the brain make our brains big

Jan Löwe

Molecular mechanisms of SMC Complexes

Kelly Nguyen

Visualization of mammalian telomeric complexes

John O'Neill

What makes mammalian cells tick?

Lori Passmore

Mechanistic insight into macromolecular machines

Protein and Nucleic Acid Chemistry project

Neuroimmune crosstalk in infection and cancer

Lalita Ramakrishnan

Cell biology underlying host-mycobacterium interactions

Felix Randow

LPS ubiquitylation and innate immunity

Christopher Russo

Physics of ion interaction with cryoEM specimens

Sjors Scheres

Cryo-EM studies of amyloids in neurodegeneration

Marta Shahbazi

How to become a germ cell

Chris Tate

Cryo-EM structures of GPCRs from pathogenic fungi

Joseph Yeeles

Structures of the human replisome

Suyang Zhang

Mechanism of transcription-coupled splicing

Marta Zlatic

Circuit basis of learning and action-selection

The LMB exceptionally considers applications for research-only MPhil students provided they obtain their own competitive funding and have the support of a group leader in the Laboratory. For information contact phdenq.