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MRC Laboratory of Molecular Biology

MRC Laboratory of Molecular Biology

One of the world's leading research institutes, our scientists are working to advance understanding of biological processes at the molecular level - providing the knowledge needed to solve key problems in human health.

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Home > Research > Neurobiology

Neurobiology Division

One of the biggest challenges facing the biological sciences is to understand how brains can give rise to minds. The goal of the Division is to explore the properties of nerve cells at a fundamental level. What are the mechanisms that determine the special abilities of nerve cells to rapidly transmit and process information? What are the rules by which communication between small numbers of nerve cells in the intact brain gives rise to simple behaviours? What are the molecular processes that lead to common dementias and movement disorders, such as Alzheimer’s disease and Parkinson’s disease?

Group Leaders and MRC Investigators

  • Radu Aricescu - The structural biology of neuronal connectivity
  • Diana Arseni - Lysosomal TMEM106B in brain ageing and disease
  • Anne Bertolotti - Understanding and manipulating cellular resilience in health and disease
  • Albert Cardona - Experimental and comparative connectomics
  • Michel Goedert - Molecular mechanisms of neurodegeneration
  • Ingo Greger - AMPA receptor biogenesis, structure and function
  • Michael Hastings - Neurons and biological timing: molecular neurobiology of the circadian clock
  • Gregory Jefferis - Genes, Circuits and Behaviour in Drosophila
  • Joergen Kornfeld - Connectomics of learned behaviour
  • Harvey McMahon - Membrane curvature as an organizing principle for eukaryotic cell biology
  • Jing Ren - Developmental assembly of the serotonin system
  • Benjamin Ryskeldi-Falcon - Pathological protein assembly in neurodegenerative diseases
  • William Schafer - Cellular and molecular mechanisms of behaviour
  • Marco Tripodi - Neural circuits for goal-oriented actions
  • Marta Zlatic - Circuit mechanisms of learning and action-selection


Emeritus

  • Nigel Unwin - Nicotinic acetylcholine receptor

Past Group Leaders 2009 - 2024

  • Tiago Branco - Moved to the Sainsbury Wellcome Centre, London, June 2016
  • Bazbek Davletov - Moved to the University of Sheffield, September 2012
  • Leon Lagnado - Moved to the University of Sussex, December 2013
  • Rebecca Taylor - Moved to the University of East Anglia, December 2022
  • Stephen Williams - Moved to the University of Queensland, Australia, December 2009


Joint Heads of Division:
Anne Bertolotti & Greg Jefferis

Divisional Administrator:
Savannah Kumari

Assistant Divisional Administrator:
Max Behzadi

Division of Neurobiology,
MRC Laboratory of Molecular Biology,

Francis Crick Avenue,
Cambridge Biomedical Campus,
Cambridge CB2 0QH,
UK.

Tel: +44 (0) 1223 267050

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Research

  • Goals and Research Focus
  • Cell Biology
  • Neurobiology
    • Initiative with the Department of Clinical Neurosciences
  • Protein and Nucleic Acid Chemistry
    • Centre for Chemical and Synthetic Biology
  • Structural Studies
  • Molecular Immunity Unit
  • Technology Transfer
    • History Of Technology Transfer
    • Neonatal Mouse Anaesthetisation Mould Request Form
    • Chinlab Software
    • Examples of Recent Technology Transfer Initiatives
      • Bicycle Therapeutics
      • Mesolens Microscopy
      • Gold EM Support Grids
      • In Vitro Compartmentalization (IVC)
      • CombiPuck
      • SiR (Self-inactivating Rabies virus)
      • MORPHEUS III
      • Trim-Away
      • PepGen
      • Raphin 1
      • Transgenic mice expressing human P301S tau protein (continued success since 2002)
      • Therapeutic Antibodies
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    • Macromolecular Crystallisation
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    • Statistics Course 2014
    • RNA-seq course 2020
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Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK. 01223 267000

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