2024
Ng-Blichfelt, J.-P., Stewart, B.J., Clathworthy, M.R., Williams, J.M., and Röper, K*. (2024) Identification of a core transcriptional program driving the human renal mesenchymal-to-epithelial transition. bioRxiv: https://doi.org/10.1101/2023.04.30.538857, accepted for publication in Developmental Cell
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Graphical-Abstract_Ng-Blichfeldt2-1024x1024.jpg)
2023
Peterson, J., Balogh Sivars, K. Bianco, A., and Röper, K*. (2023.) Toll-like receptor signalling via IRAK4 affects epithelial integrity and tightness through regulation of junctional tension. Development 150 (24): dev201893; cover picture in Development
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/DEV_150_24_ForAuthor-789x1024.jpg)
Ashour, D.J., Durney, C.H., Planelles-Herrero, V.J., Stevens, T.J., Feng,J.J. and Röper, K*. (2023) Zasp52 strengthens whole embryo tissue integrity through supracellular actomyosin networks. Development 150, dev20123 ; highlighted as Preprint Highlight in MBoC https://www.molbiolcell.org/doi/10.1091/mbc.P22-10-1006; highlighted as Research Highlight in Development; cover picture in Development
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/DEV_150_7_ForAuthor-789x1024.jpg)
2021
Sánchez-Corrales, Y. E., Blanchard, G. B., & Röper, K*. (2021) Correct regionalisation of a tissue primordium is essential for coordinated morphogenesis. eLife; 2021;0:e72369. https://doi.org/10.7554/eLife.72369
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Screenshot-2020-09-28-at-15.55.39-1024x417.png)
Gillard, G., Girdler, G. & Röper, K. (2021). A release-and-capture mechanism generates an essential non-centrosomal microtubule array during tube budding. Nature Communications 12: 4096 https://doi.org/10.1038/s41467-021-24332-0
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/banner-1-for-tweet-1024x190.jpg)
2020
Ambrosini, A., and Röper K. (2020) “Neur”al brain wave: Coordinating epithelial-to-neural stem cell transition in the fly optic lobe. Invited Spotlight for J. Cell Biol. 219(11):e202009040. doi: 10.1083/jcb.202009040.
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/overview-fig-for-web-spotlight-arnbaud.png)
Ng-Blichfeldt, J.-P. and Röper, K. (2020). Mesenchymal to epithelial transitions (MET) in development and cancer and the role of MET-TFs. Invited review for Methods in Molecular Biology 2179, ISBN 978-1-0716-0778-7
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/overview-fig-for-web-1024x744.png)
Gillard, G.,and Röper, K. (2020). Control of cell shape during epithelial morphogenesis: recent advances.Invited review for Curr. Opin. Genet. Dev. 63: 1-8, doi.org/10.1016/j.gde.2020.01.003
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Screenshot-2020-09-28-at-15.58.18-1024x552.png)
Röper, K. (2020) Microtubules enter centre stage for morphogenesis. Invited review for Philos. Trans. R. Soc. B, Biol. Sci.375, 20190557, DOI : 10.1098/rstb.2019.0557
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Screenshot-2020-09-28-at-15.57.20-1024x801.png)
Sidor, C., Stevens, T., Jin, L., Boulanger, J., Röper, K. (2020). Rho kinase planar polarisation at tissue boundaries depends on phospho-regulation of membrane residence time, Developmental Cell, 52: 364–378., https://doi.org/10.1016/j.devcel.2019.12.003
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/droppedImage_1-1.jpg)
2018
Röper, K. (2018) Quantitative imaging and the effect of tissue topology on morphogenesis. Developmental Cell. 47(5):537-538. doi: 10.1016/j.devcel.2018.11.023.; PMID: 30513296
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Spotlight_Figure_Roeper-1024x984.jpg)
Sánchez-Corrales, Y.E., Röper K. (2018). Radially-patterned cell behaviours during tube budding from an epithelium. eLife;7:e35717 DOI: 10.7554/eLife.35717
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Screen-Shot-2018-07-18-at-13.18.45.jpg)
Röper, K., and Bustelo, X.R. (2018) Editorial overview: New concepts and experimental approaches to understand development, tissue regeneration, and human disease. Curr. Opin. Cell Biol.; 55:iii-v.; doi: 10.1016/j.ceb.2018.09.006.; PMID: 30287131
Sánchez-Corrales, Y.E., Röper K. (2018). Alignment of cytoskeletal structures across cell boundaries generates tissue cohesion during organ formation. Current Opinion in Cell Biology, 55:104–110 . doi.org/10.1016/j.ceb.2018.07.001
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Screen-Shot-2018-07-18-at-13.42.19.jpg)
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Screen-Shot-2018-07-18-at-13.42.27.jpg)
2017
Sidor C, Röper K. (2017). Squeezing out in a “tug of war”: The role of myosin in neural stem cell delamination. J. Cell Biology. 1;216(5):1215-1218. doi: 10.1083/jcb.201702116
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Screen-Shot-2017-06-29-at-15.33.17.jpg)
Takács, Z., Jankovics, F., Vilmos, P., Lénárt, P., Röper, K., and Erdélyi, M. (2017) The spectraplakin short stop is an essential microtubule regulator involved in epithelial closure in Drosophila., J. Cell Science. 130:712-724.
2016
O’Donnell, M. A. (2016). Katja Röper: Deciphering tissue origami. J. Cell Biology, 215(2), 140–141. http://doi.org/10.1038/nrm3568
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Screen-Shot-2016-10-28-at-15.39.04.jpg)
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Screen-Shot-2016-10-28-at-15.39.28.jpg)
Sidor, C. and Röper, K. (2016), Genetic control of salivary gland tubulogenesis in Drosophila. in ‘Organogenetic Gene Networks’ pp 125-149,DOI 10.1007/978-3-319-42767-6_5, ISBN 978-3-319-42765-2 (invited review).
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Screen-Shot-2016-09-15-at-17.54.23.jpg)
Girdler, G.C., Applewhite, D.A., Perry, W.M.G., Rogers, S.L., and Röper, K. (2016). The Gas2 family protein Pigs is a microtubule +TIP that affects cytoskeleton organisation. J. Cell Science. 129: 121-134.
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Gemma_coverPic.png)
2015
Röper, K. (2015), Integration of cell-cell adhesion and contractile actomyosin activity during morphogenesis. Curr. Top. Dev. Biol. 112:103-27.
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Screen-Shot-2015-08-26-at-11.03.14.jpg)
2014
Girdler, G., and Röper, K. (2014), Controlling cell shape changes during salivary gland tube formation in Drosophila. Sem.Cell Dev.Biol., 1–8. doi:10.1016/j.semcdb.2014.03.020.
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Screen-Shot-2014-03-31-at-16.44.48.jpg)
Booth, A.J.R., Blanchard, G.B., Adams, R.J. and Röper, K. (2014), A dynamic microtubule cytoskeleton directs medial actomyosin function during tube formation. Developmental Cell, 29(5), 562–576. doi:10.1016/j.devcel.2014.03.023.
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Booth_graphical-abstract_b.jpg)
2013
Röper, K. (2013). Supracellular actomyosin assemblies during development. Bioarchitecture, 3(2), 45–49. doi:10.4161/bioa.25339.
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Screen-Shot-2013-08-07-at-13.59.53.jpg)
Thompson, B, Pichaud, F. and Röper, K., (2013) Sticking together the Crumbs – an unexpected function for an old friend. Nature Reviews Molecular Cell Biology.14(5), 307–314 (Review)
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Screen-Shot-2013-06-06-at-12.19.20.jpg)
2012
Röper, K. (2012) Anisotropy of Crumbs and aPKC drives myosin cable assembly during tube formation. Developmental Cell 23:939-953.
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/DrosoImageAward_pic3.jpg)
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/droppedImage-4.jpg)
2010
Pines, M.K., Housden, B.E., Bernard, F., Bray, S.J., and Röper, K., (2010)The cytolinker Pigs is a direct target and a negative regulator of Notch signalling. Development 137: 913-22. (featured in ‘In this issue’; Faculty of 1000: ‘Recommended’).
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Screen-Shot-2013-06-06-at-12.17.17.jpg)
2009
Maybeck, V. and Röper, K., (2009) A targeted gain-of-function screen identifies genes affecting salivary gland morphogenesis/tubulogenesis in Drosophila. Genetics 181: 543–565.
2007
Röper, K., (2007) Rtnl1 is enriched in a specialized germline ER that associates with ribonucleoprotein granule components. J. Cell Science. 120: 1081-1092.
2005
Röper, K., Mao, Y., and Brown N.H. (2005) Contribution of sequence variation in Drosophila actins to their incorporation into actin-based structures in vivo. J. Cell Science. 118: 3937-3948. (featured as cover picture).
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/JCScover.jpg)
2004
Röper, K*., and Brown, N.H. (2004) A spectraplakin is enriched on the fusome and organizes microtubules during oocyte specification in Drosophila. Current Biology. 14: 99-110. (*corresponding author).
2003
Röper, K. and Brown, N.H. (2003) Maintaining epithelial integrity: a function for gigantic spectraplakin isoforms in adherens junctions. J. Cell Biology. 162: 1305-1315. (featured in ‘In this issue’ and as cover picture).
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/JCBcover.jpg)
![](https://www2.mrc-lmb.cam.ac.uk/groups/kroeper/wp-content/uploads/sites/27/Screen-Shot-2013-06-06-at-12.16.59.jpg)
2002
Röper K., Gregory S.L., and Brown N.H. (2002) The ‘spectraplakins’: cytoskeletal giants with characteristics of both spectrin and plakin families. J. Cell Science. 115:4215-4225. (Review; Faculty of 1000: ‘Must read’).
Pre Postdoc
Kosodo,Y.*, Röper, K.*, Haubensak, W.*, Marzesco, A.M., Corbeil, D., and Huttner, W.B. (2004) Asymmetric distribution of the apical plasma membrane during neurogenic divisions of mammalian neuroepithelial cells. EMBO J. 23:2314-2324. (* joint first authors; Faculty of 1000: ‘Must read’).
Corbeil D., Röper K., Fargeas C.A., Joester A., and Huttner W.B. (2000) Prominin: a story of cholesterol, plasma membrane protrusions and human pathology. Traffic 2:82-91. (Review).
Röper, K., Corbeil, D., and Huttner, W.B. (2000) Retention of prominin in microvilli reveals distinct cholesterol–based lipid microdomains in the apical plasma membrane. Nature Cell Biol. 2:582-592.
Röper, K., Corbeil, D., and Huttner, W.B. (2000) Microvilli, lipid microdomains and cell polarity: a potential role of the lipid bilayer in the retention of prominin in apical microvillar membranes. NATO Science Series. Protein, lipid and membrane traffic: pathways and targeting. (Edit.: Jos A.F. Op den Kamp), IOS Press, pp73-84. (Book Chapter),
Corbeil, D.*, Röper, K.*, Hellwig, A., Tavian, M., Miraglia, S., Watt, S., Simmons, P., Peault, B., Buck, D.W., and Huttner, W.B. (2000) The human AC133 hematopoietic stem cell antigen is also expressed in epithelial cells and targeted to plasma membrane protrusions. J. Biol. Chem., 275: 5512-5520. (* joint first authors).
Maw, M.A., Corbeil, D., Koch, J., Hellwig, A., Wilson-Wheeler, J.C., Bridges, R.J., Kumaramanickavel, G., John, S., Nancarrow, D., Röper, K., Weigmann, A., Huttner, W.B., and Denton, M.J. (2000) A frameshift mutation in prominin (mouse)-like 1 causes human retinal degeneration. Hum. Mol. Genet. 9:27-34.
Corbeil, D.*, Röper, K.*, Hannah, M.J., Hellwig, A., and Huttner, W.B. (1999) Selective Localization of the Polytopic Membrane Protein Prominin in Microvilli of Epithelial Cells- A Combination of Apical Sorting and Retention in Plasma Membrane Protrusions. J. Cell Sci. 112:1023-1033. (* joint first authors).
Corbeil, D., Röper, K., Weigmann, A., and Huttner, W.B. (1998) AC133 hematopoietic stem cell antigen: human homologue of mouse kidney prominin or distinct member of a novel protein family? Blood 91, 2625-2626.