Amy worked in the Passmore lab for three months over the summer after finishing her second year at the University of Cambridge.

She moved on to do a PhD in New Zealand with Juliet Gerrard and is currently a post-doc in Eindhoven.

Twitter: @OodlesOfYewdall

Alexander joined us in October 2012 after studying biology at the University of Zurich. Originally from Germany, he is interested in mRNA deadenylation.

He completed his MPhil in the Passmore lab in 2014 and is now a PhD student in Elena Conti’s group at the Max Planck Institute of Biochemistry in Martinsried.

Birthe completed a PhD with Stewart Shuman at Sloan-Kettering Institute in New York. She studied anticodon nuclease-mediated tRNA damage and its repair. Birthe is originally from Germany and studied at Tübingen.

Birthe worked jointly with Murray Stewart’s lab for one year from Feb 2012.

Currently Post-doc at the Karolinska Institute

Katrin completed her PhD in Protein Biochemistry at the Max Planck Institute for Biophysical Chemistry (Goettingen, Germany). 

She moved to Cambridge and joined the Passmore lab in April 2009 where she studied mRNA polyadenylation and deadenylation.

Currently working at Immunocore.

James studied at the University of York where he gained his passion for structural biology. He worked in Piotr Sliz’s lab (Harvard Medical School) for a year before joining us in October 2013. James is interested in structures of proteins involved in post-transcriptional gene regulation. He finished his PhD in 2017 and is now an Investigator Scientist in the lab.

Email: jstowell [at] mrc-lmb.cam.ac.uk

Tayla worked in the lab during the summer of 2013 after her third year of university. She studied Biochemistry at the University of Wisconsin, Madison. Tayla was selected to take part in the Summer Cambridge and Oxford Research Experience (SCORE).

Currently a PhD student at University of Washington in Seattle.

Twitter: @TaylaOlsen

Ashley moved all the way from New Zealand to join the lab in October 2010.  He studied at the University of Waikato and has a background in chemistry and biophysics.

Ashley was funded by a Woolf Fisher Trust PhD Scholarship. He successfully defended his thesis in April 2014. He then moved to a position at Innovia Technology and is now working at AstraZeneca.

Jana joined the lab in October 2010 after completing her undergraduate and masters studies at the University of Heidelberg.  She is interested in the structure and function of proteins involved in regulating gene expression.

Jana was funded by a LMB Scholarship. She successfully defended her thesis in July 2014 and started a job at Domainex.

Gillian is from Canada and studied at Simon Fraser University and the University of Leicester. She started in Nov 2012 and worked with both the Passmore and Carter labs. Gillian set up the Multibac system for expression of multi-protein complexes in insect cells.

Gillian did her PhD at the University of Victoria in Canada and is currently a post-doc in Berlin.

Twitter: @GilleighD

Fabienne is studying for her masters degree at the Ruprecht-Karls-University in Heidelberg. She joined the Passmore lab for a 3 month internship in September 2014.

She is now doing a PhD at the University of Michigan

Twitter: @TF_Birkle

Ina started her PhD in October 2012 and worked with Jernej Ule’s lab. She defined the RNA binding patterns of specific proteins using CLIP technology. Ina was funded by through a Marie Curie Initial Training Network RNPnet.

She did a post-doc in Mattias Hentze’s lab (EMBL Heidelberg) and is now a Group Leader at the Max Planck Institute for Biology of Ageing.

Twitter: @ina_huppertz

Kathryn worked in the lab for 3 months with James and Ana. She did TAP purifications from yeast as well as working with RNA binding proteins. Kathryn had just finished her 2nd Year in biochemistry at The Queen's College, Oxford University.

Chris completed his PhD in Applied Physics at Harvard University in the lab of Jene Golovchenko and Daniel Branton. He has specific expertise in electron microscopy and applied this to projects in the Passmore lab.

Chris joined in November 2011 and developed new substrates for cryo-EM. He started his own group at LMB in Jan 2016, supported by an Early Career Fellowship from the Leverhulme Trust.

Now a group leader at MRC LMB

Website: www.mrc-lmb.cam.ac.uk/crusso/

Twitter: @cjrlab

Peter worked in the lab after finishing his third year of undergraduate studies. He was a student at University of Edinburgh but spent a year in Canada at UBC on an exchange program. He worked with Chris Hill.

Currently on a Masters program

Terence joined the Passmore group in October 2016 to study mechanisms of mRNA de-adenylation. Prior to this, he studied Biochemistry at the University of Oxford where he developed an interest in structural biology. He finished his PhD in 2020. He was supported by a Hershel Smith studentship.

Terence is now doing a post-doc in Jue Chen’s lab at Rockefeller.

Twitter: @terencetltang

Ann worked in the lab for three months to help out with protein preps and in vitro transcriptions. She previously worked at the LMB with Venki Ramakrishnan.

Eeson studied at the University of Cambridge and did his PhD with Ashok Venkitaraman at the MRC/Hutchison Cancer Cell Unit.  He has a specific interest in mechanisms of DNA repair.

Eeson joined us in February 2010 and is purifying complexes from higher eukaryotes. He is working on the FA core complex.

Currently Senior Scientist at Artios Pharma

Vytaute first joined the lab in 2017 after her third year at Cambridge University (Queens’ College) as a summer student. She worked on the nuclease activity of CPF with Chris Hill for the summer. She re-joined the lab as a PhD student (Oct 2018 - Sept 2022) and a short postdoc (until Feb 2023) when she reconstituted pre-mRNA 3’ cleavage by CPSF for the first time.

Vytaute is currently a postdoc in Clemens Plaschka’s lab at the IMP in Vienna.

Twitter: @VBoreikaite

Chris Hill joined the lab in August 2015 to work on CPF, focusing on the nuclease. Chris completed his PhD studies in Janet Deane and Randy Read's laboratories at the Cambridge Institute for Medical Research (CIMR) working on structural and functional studies of β-galactocerebrosidase, the defective enzyme in Krabbe disease.

Chris started his own group at the University of York in 2021.

Website: https://www.york.ac.uk/biology/our-staff/chris-hill/

Twitter: @chillzaa

Manuel joined the lab in January 2018. He did his PhD with Marina Mapelli at the European Institute of Oncology in Milan where he studied the molecular mechanisms driving mitotic spindle orientation. Manuel has been awarded an EMBO long-term fellowship for his work in the lab.

Manuel is now a post-doc in Nico Thomä’s lab at EPFL in Lausanne

Twitter: @_M_Carminati

Pablo studied the structure of the Cpf1 CRISPR endonuclease during his PhD with Guillermo Montoya at the University of Copenhagen. He joined the lab in February 2018 to study DNA repair complexes. Pablo was awarded an EMBO long-term fellowship for his work in the lab.

Email: palcon [at] mrc-lmb.cam.ac.uk

Twitter/X: @palconh

Michael studied at the University of Sydney where he worked in Joel Mackay’s lab. He is specifically interested in RNA binding proteins and gene regulation. Michael joined the lab in October 2013.

He went on to do a post-doc in Albert Weixlbaumer’s lab at IGBMC Strasbourg. Michael started his own lab at the John Innes Centre in 2022.

Website: https://www.jic.ac.uk/people/michael-webster/

Twitter: @WebsterMichael0

Alžběta worked with Terence on Pan2-Pan3 for 3 months over the summer. She had just finished her second year studying Natural Sciences at the University of Cambridge (Peterhouse College).

Currently a PhD student at the Crick Institute.

Eleanor joined the lab for 3 months over the summer of 2018. She was studying at the University of Cambridge (Peterhouse College) and had just finished her third year.

She worked in the lab with Juan to study the CPF nuclease module using structural and functional approaches. Now a PhD student at the Cancer Research UK Cambridge Institute.

Twitter: @EleanorSheekey

Blog: https://asheekeyscienceblog.com/

Max joined the lab as a Masters student from University of Heidelberg in October 2018. He studied deadenylation. He was awarded the GBM Master prize for the best thesis in Biochemistry in Heidelberg.

Max started his PhD in Martin Beck’s laboratory in autumn 2019.

Eva joined the lab in summer 2019 to study deadenylase complexes. She completed her PhD with Markus Wahl at Freie Universität Berlin working on RNA helicases of the spliceosome using x-ray crystallography, biophysical and biochemical methods. She was funded by a DFG Research Fellowship and gained new insight into the link between CCR4-NOT and translation.

Eva is now an independent junior group leader at the Freie Universität in Berlin.

Twitter: @AbsmeierEva

Cemre completed her PhD in Ditlev Brodersen’s lab at the University of Aarhus where she studied (p)ppGpp synthesis by bacteria. Cemre visited the lab for two months in 2018 to do some electron microscopy and biochemical experiments.

She joined the lab as a post-doc in December 2019 to study poly(A) tail removal. Cemre was funded by a NovoNordisk Foundation Fellowship.

Cemre currently works as a development scientist at Novo Nordisk in Copenhagen.

Twitter: @mcemremnv

Ananth arrived in October 2015 to join the CPF team, with a specific interest in the polyA polymerase. He studied in India and during this time designed a microbial fuel cell. He then did a Masters at Nagoya University in Japan, focussing on bacterial flagella. Ananth was supported by a Gates Cambridge Studentship.

Currently a post-doc with Anna Marie Pyle at Yale.

Twitter: @ananthb3lyp

Tamara studied at the University of Vienna. She joined the lab as a PhD student in October 2019 and worked on the Fanconi Anaemia DNA repair pathway. She showed how DNA-damage kinases regulate the FANCD2-FANCI DNA clamp.

Tamara is currently a post-doc in Francesca Ester Morreale’s lab at the Crick Institute in London.

Twitter: @TamaraSijacki

Shabih did his PhD with Sarah Butcher at the University of Helsinki, studying the structures of picornaviruses and mechanisms of RNA packaging. He joined the Passmore group in April 2017 where he used cryo-EM to study the Fanconi anaemia pathway.

He started his own group at WEHI in Melbourne in 2021.

Twitter: @ShabihShakeel

Ana joined the lab in October 2014 after completing her PhD with Victoriano Valpuesta at the University of Málaga and José Márquez at EMBL Grenoble.

In the Passmore lab, Ana worked on the polymerase module of CPF. She was supported by an EMBO long-term fellowship and was awarded the 2019 Biochemical Society Early Career Award, the 2019 Brenner post-doc prize and the 2019 FEBS Anniversary prize award for her work.

She started her own lab at the Human Technopole in Milan in 2021.

https://humantechnopole.it/en/people/ana-casanal/

Twitter: @AnaCasanal

Giselle was a summer student in the lab in 2021. She worked with James on targeted deadenylation on the Ccr4-Not complex. She was in the lab between her third and fourth years at University of Cambridge (Biochemistry).

Now a PhD student in John Diffley’s lab at the Crick Institute.

Twitter: @gsiellecllee

Siggi is a PhD student in Kay Grünewald’s lab in Hamburg where he is studying the structures of viral proteins essential for transcription and translation. He visited the lab for 2 months in 2021.

Francis is a post-doc in Juri Rappsilbers lab in Berlin. He is an expert on cross-linking mass spectrometry and collaborates with us. He visited the lab for one month in 2020.

Holly studied at the University of Birmingham. She joined the lab as a PhD student in October 2021. She is studying activation of cleavage by the CPF complex.

Email: hfagarasan [at] mrc-lmb.cam.ac.uk

Twitter/X: @FagarasanHolly

Tim was a summer student in the lab in 2022. He worked with Tamara and Pablo on Fanconi Anaemia DNA repair.

Tim studies Molecular and Cellular Biochemistry at the University of Oxford and had just finished his second year.

Sylvie was a summer student in the lab in 2022. She worked with James on Ccr4-Not.

Sylvie studies Biomedical Sciences at the University of York and had just finished her second year.

Matti is a new PI at University of Turku. He visited the lab for 2 months to learn how we study mRNA polyadenylation in vitro.

Juan joined the lab in June 2017. He studied Pol II during his PhD at the University of Wisconsin-Madison in Aseem Ansari’s lab. In the Passmore lab, he combined functional work in yeast with structural and biochemical studies.

Twitter: @rodriguezmol

Marc is originally from Austria and worked with Mariann Bienz at the LMB from 2004-2022. He joined the Passmore lab in 2023 to study the mRNA 3’-end processing machinery.

Email: mfiedler [at] mrc-lmb.cam.ac.uk

Josh did his PhD and first post-doc with Steve West at the University of Exeter. This work focused on both promoter proximal and canonical transcription termination by RNA polymerase II. In the Passmore lab, Josh is studying the sequence specificity of pre-mRNA 3’ cleavage.

Email: jeaton [at] mrc-lmb.cam.ac.uk

Megan studied at the University of Bristol and joined the lab as a PhD student in 2023. She is studying mRNA deadenylation by Pan2-Pan3.

Email: mgough [at] mrc-lmb.cam.ac.uk

Yichao joined the Passmore lab for a summer studentship in 2023 after his second year studying Natural Sciences at the University of Cambridge. Yichao worked with the Fanconi team on DNA repair.