Amy Yewdall

 

Lori is originally from Canada and studied Biochemistry at the University of British Columbia in Vancouver.  In 1999, she moved to the UK for her PhD studies at The Institute of Cancer Research.  After completing her PhD, Lori moved to Cambridge where she was a Career Development Fellow at the MRC Laboratory of Molecular Biology, funded by a Beit Memorial Fellowship for Medical Research.  In 2009, Lori became a Group Leader at the MRC-LMB. She is also a fellow of Clare Hall.


Lori was awarded an ERC Starting Grant in 2011 and an ERC Consolidator Grant in 2017. She was elected into the EMBO Young Investigator Programme in 2015 and EMBO Membership in 2018.


For more details see Lori’s CV.

Twitter: @lapassmore

People

Passmore Lab, MRC Laboratory of Molecular Biology, Cambridge UK

Lori A. Passmore, PhD 

Group Leader

Lab photos can be found here!

Summer Student 2010


Amy worked in the Passmore lab for three months over the summer after finishing her second year at the University of Cambridge.


Currently PhD student in New Zealand with Juliet Gerrard.

Lab Alumni

Alexander Kögel

MPhil student 2012-2014


Alexander joined us in October 2012 after studying biology at the University of Zurich. Originally from Germany, he is interested in mRNA deadenylation.


He completed his MPhil in the Passmore lab in 2014 and is now a PhD student in Elena Conti’s group at the Max Planck Institute of Biochemistry in Martinsried.


Birthe Meineke, PhD

Post-doctoral Fellow 2012


Birthe completed a PhD with Stewart Shuman at Sloan-Kettering Institute in New York. She studied anticodon nuclease-mediated tRNA damage and its repair. Birthe is originally from Germany and studied at Tübingen.


Birthe worked jointly with Murray Stewart’s lab for one year from Feb 2012.


Currently Post-doc at the Karolinska Institute

Katrin Wiederhold, PhD

Post-doctoral Fellow 2009-2013


Katrin completed her PhD in Protein Biochemistry at the Max Planck Institute for Biophysical Chemistry (Goettingen, Germany). 


She moved to Cambridge and joined the Passmore lab in April 2009 where she studied mRNA polyadenylation and deadenylation.


Currently working at Immunocore.

James Stowell, PhD

PhD student/Post-doc


James studied at the University of York where he gained his passion for structural biology. He worked in Piotr Sliz’s lab (Harvard Medical School) for a year before joining us in October 2013. James is interested in structures of proteins involved in post-transcriptional gene regulation. He finished his PhD in 2017.


Email: jstowell [at] mrc-lmb.cam.ac.uk


Tayla Olsen

Summer Student 2013

Tayla worked in the lab during the summer of 2013 after her third year of university. She is studying Biochemistry at the University of Wisconsin, Madison.


Tayla was selected to take part in the Summer Cambridge and Oxford Research Experience (SCORE).


Currently at University of Washington in Seattle.

November 2018

Ashley Easter

PhD Student 2010-2014



Ashley moved all the way from New Zealand to join the lab in October 2010.  He studied at the University of Waikato and has a background in chemistry and biophysics.


Ashley was funded by a Woolf Fisher Trust PhD Scholarship. He successfully defended his thesis in April 2014. He then moved to a new position at Innovia Technology and is now working at AstraZeneca.

Photo credit : MRC (Martin Phelps)


Jana joined the lab in October 2010 after completing her undergraduate and masters studies at the University of Heidelberg.  She is interested in the structure and function of proteins involved in regulating gene expression.


Jana was funded by a LMB Scholarship. She successfully defended her thesis in July 2014 and started a job at Domainex.

Jana Wolf

PhD Student 2010-2014


Gillian is from Canada and studied at Simon Fraser University and the University of Leicester.


Gillian set up the Multibac system for expression of multi-protein complexes in insect cells. She started in Nov 2012 and worked with both the Passmore and Carter labs.


Gillian started a PhD a the University of Victoria in Canada in September 2014.


Gillian Dornan

Research Assistant 2012-2014

Fabienne Birkle

Masters student, autumn 2014


Fabienne is studying for her masters degree at the Ruprecht-Karls-University in Heidelberg. She joined the Passmore lab for a 3 month internship in September 2014.


She begins a PhD in the US in 2016.


Ana Casañal, PhD

Post-doc

Ana joined the lab in October 2014 after completing her PhD with Victoriano Valpuesta at the University of Málaga and José Márquez at EMBL Grenoble. She studied the molecular basis of strawberry fruit ripening using structural, biochemical and genomics methods.


In the Passmore lab, Ana is working on the phosphatase activity of the polyadenylation complex. She is supported by an EMBO long-term fellowship and was awarded the 2019 Biochemical Society Early Career award for her work.


Email: acasanal [at] mrc-lmb.cam.ac.uk

Twitter: @AnaCasanal

Ina Huppertz

PhD student 2012-2015


Ina started her PhD in October 2012 and worked with Jernej Ule’s lab. She defined the RNA binding patterns of specific proteins using CLIP technology.


Ina was funded by through a Marie Curie Initial Training Network RNPnet.


Now doing a post-doc in Mattias Hentze’s lab (EMBL Heidelberg).

  Kathryn Shelley

Summer student 2015

Kathryn worked in the lab for 3 months with James and Ana. She did TAP purifications from yeast as well as working with RNA binding proteins. Kathryn just finished her 2nd Year in biochemistry at The Queen's College, Oxford University.

Ananthanarayanan Kumar

PhD student

Ananth arrived in October 2015 to join the CPF team, with a specific interest in the polyA polymerase. He studied in India and during this time designed a microbial fuel cell. He then did a Masters at Nagoya University in Japan, focussing on bacterial flagella.


Supported by a Gates Cambridge Studentship.


Email: akumar [at] mrc-lmb.cam.ac.uk

Twitter: @ananthb3lyp

Christopher Russo, PhD

Post-doctoral Fellow 2011-2015


Chris completed his PhD in Applied Physics at Harvard University in the lab of Jene Golovchenko and Daniel Branton. He has specific expertise in electron microscopy and applied this to projects in the Passmore lab.


Chris joined in November 2011 and developed new substrates for cryo-EM. He started his own group at LMB in Jan 2016, supported by an Early Career Fellowship from the Leverhulme Trust.


Now a group leader at MRC LMB

Website: www.mrc-lmb.cam.ac.uk/crusso/

Photo credit : MRC (Martin Phelps)

Peter Kubik

Summer student 2016

Peter worked in the lab after finishing his third year of undergraduate studies. He was a student at University of Edinburgh but spent a year in Canada at UBC on an exchange program. He worked with Chris Hill.


Currently on a Masters program

Terence Tang

PhD student

Terence joined the Passmore group in October 2016 to study mechanisms of mRNA de-adenylation. Prior to this, he studied Biochemistry at the University of Oxford where he developed an interest in structural biology.


Supported by a Hershel Smith studentship.


Email: ttang [at] mrc-lmb.cam.ac.uk

Twitter: @terencetltang

Ann Kelley

Research support 2017

Ann worked in the lab for three months to help out with protein preps and in vitro transcriptions. She previously worked at the LMB with Venki Ramakrishnan.

Eeson Rajendra, PhD

Post-doctoral Fellow 2010-2016


Eeson studied at the University of Cambridge and did his PhD with Ashok Venkitaraman at the MRC/Hutchison Cancer Cell Unit.  He has a specific interest in mechanisms of DNA repair.


Eeson joined us in February 2010 and is purifying complexes from higher eukaryotes. He is working on the FA core complex.


Currently Senior Scientist at Artios Pharma

Shabih Shakeel, PhD

Post-doc

Shabih did his PhD with Sarah Butcher at the University of Helsinki, studying the structures of picornaviruses and mechanisms of RNA packaging. He joined the Passmore group in April 2017 where he is using cryo-EM.


Email: sshakeel [at] mrc-lmb.cam.ac.uk

Twitter: @ShabihShakeel

Juan Rodríguez Molina, PhD

Post-doc

Juan joined the lab in June 2017. He studied Pol II during his PhD at the University of Wisconsin-Madison in Aseem Ansari’s lab. He is doing functional work in yeast in the Passmore lab.


Email: jrodrigu [at] mrc-lmb.cam.ac.uk

Twitter: @rodriguezmol

Vytaute Boreikaite

Summer student 2017/PhD student

Vytaute first joined the lab after her third year at Cambridge University (Queens’ College) as a summer student. She worked on the nuclease activity of CPF with Chris Hill for the summer.


She joined the lab as a PhD student in October 2018 and will continue investigating mRNA 3’ end formation.


Email: vborei [at] mrc-lmb.cam.ac.uk

Chris Hill, PhD

Post-doc 2015 – 2017


Chris Hill joined the lab in August 2015 to work on CPF, focusing on the nuclease. Chris completed his PhD studies in Janet Deane and Randy Read's laboratories at the Cambridge Institute for Medical Research (CIMR) working on structural and functional studies of β-galactocerebrosidase, the defective enzyme in Krabbe disease.


Currently Research Associate in Dept of Pathology, University of Cambridge.


Twitter: @chillzaa

Manuel Carminati

Post-doc

Manuel joined the lab in January 2018. He did his PhD with Marina Mapelli at the European Institute of Oncology in Milan where he studied the molecular mechanisms driving mitotic spindle orientation. Manuel has been awarded an EMBO long-term fellowship for his work in the lab.


Email: mcarmina [at] mrc-lmb.cam.ac.uk

Pablo Alcón Hernández, PhD

Post-doc

Pablo studied the structure of the Cpf1 CRISPR endonuclease during his PhD with Guillermo Montoya at the University of Copenhagen. He joined the lab in February 2018 to study DNA repair complexes. Pablo has been awarded an EMBO long-term fellowship for his work in the lab.


Email: palcon [at] mrc-lmb.cam.ac.uk

Twitter: @palconh

M. Cemre Manav

Visiting student 2018

Cemre is doing her PhD in Ditlev Brodersen’s lab at the University of Aarhus. She studies (p)ppGpp synthesis by bacteria. Cemre visited the lab for two months to do some electron microscopy and biochemical experiments.

Michael Webster, PhD

PhD student/Post-doc 2013-2018


Michael studied at the University of Sydney where he worked in Joel Mackay’s lab. He is specifically interested in RNA binding proteins and gene regulation.


Michael joined the lab in October 2013.


Currently a post-doc in Albert Weixlbaumer’s lab at IGBMC Strasbourg.

Alžběta Roeselová

Summer Student 2018

Alžběta worked with Terence on Pan2-Pan3 for 3 months over the summer. She had just finished her second year studying Natural Sciences at the University of Cambridge (Peterhouse College).


Eleanor joined the lab for 3 months over the summer of 2018. She is studying at the University of Cambridge (Peterhouse College) and just finished her third year.


She worked in the lab with Juan to study the CPF nuclease module using structural and functional approaches.


Twitter: @EleanorSheekey

Blog: https://asheekeyscienceblog.com/

Max Seidel

Masters student 2018-2019

Max is a Masters student from University of Heidelberg. He joined the lab for his Masters thesis in October 2018 and is studying deadenylation.


Max is starting his PhD in autumn 2019.

  Eleanor Sheekey

Summer Student 2018

Eva Absmeier

Post-doc

Eva joined the lab in summer 2019 to study deadenylase complexes. She completed her PhD with Markus Wahl at Freie Universität Berlin working on RNA helicases of the spliceosome using x-ray crystallography, biophysical and biochemical methods. She is funded by a DFG Research Fellowship.


Email: absmeier [at] mrc-lmb.cam.ac.uk