The LMB is delighted to announce the awarding of the 2017 Nobel Prize in Chemistry to the LMB’s Richard Henderson, jointly with Jacques Dubochet and Joachim Frank “for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution”. More…
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The MRC Laboratory of Molecular Biology (LMB) is a research institute dedicated to the understanding of important biological processes at the levels of atoms, molecules, cells and organisms. In doing so, we provide knowledge needed to solve key problems in human health.
Our scientists tackle fundamental, often difficult and long-term research problems. The LMB has made revolutionary contributions to science, such as pioneering X-ray crystallography to determine protein structures, the sequencing of DNA and the development of monoclonal antibodies. Ten Nobel Prizes have been awarded for work carried out by LMB scientists.
The LMB also promotes the application and exploitation of our research findings, both by collaboration with existing companies and the founding of new ones, helping to advance medical research and the translation and application of knowledge.
The LMB provides an unsurpassed environment for both young and established researchers, with state-of-the-art facilities and a unique scientific culture. The LMB has always been very diverse, with a truly international outlook. We currently employ men and women from over 50 countries, and LMB alumni work in research organisations across the world.
The connectome of an animal is the comprehensive map, or wiring diagram, of all the neural connections in the brain. However, an important challenge is how to make sense of this information. The nematode worm Caenorhabditis elegans, still the only animal for…
Cell growth requires the synthesis of molecules, such as nucleotides to make DNA and amino acids to make proteins. One essential building block of these is the one carbon unit. This is produced by the one carbon (1C) cycle, which requires the…
- Richard Henderson wins 2017 Nobel Prize for Chemistry
Richard Henderson from the LMB’s Structural Studies Division has been awarded the 2017 Nobel Prize […]
- The UK’s dementia research landscape: LMB is a piece of the jigsaw
The UK’s dementia research landscape is an impressive and complex jigsaw – made up of […]
- A Linear Diubiquitin-Based Probe for Efficient and Selective Detection of the Deubiquitinating Enzyme OTULIN.
Weber, A., et al.
Cell Chem Biol 24(10): 1299-1313.e7. (19th October 2017)
- Guidelines for morpholino use in zebrafish.
Stainier, DYR., et al.
PLoS Genet. 13(10): e1007000. (19th October 2017)
- Establishment of mouse expanded potential stem cells.
Yang, J., et al.
Nature 550(7676): 393-397. (19th October 2017)
- Recordings of Caenorhabditis elegans locomotor behaviour following targeted ablation of single motorneurons.
Chew, YL., Walker, DS., Towlson, EK., Vértes, PE., Yan, G., Barabási, AL., Schafer, WR.
Sci Data 4: 170156. (19th October 2017)
- Cyanamide as a prebiotic phosphate activating agent - catalysis by simple 2-oxoacid salts.
Tsanakopoulou, M., Sutherland, JD.
Chem. Commun. (Camb.) [Epub ahead of print]. (18th October 2017)
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