The LMB is responsible for many pioneering techniques, such as methods for determining the three-dimensional structures of proteins and other macromolecules, the sequencing of DNA and the development of monoclonal antibodies.
Our scientists tackle difficult, long-term research problems. At the same time they are encouraged to exploit their discoveries – through patents, licensing and business start-ups – helping to advance medical research and improve the UK’s economic competitiveness.
The spliceosome is a molecular machine, which together with RNA polymerases and ribosomes plays a critical role in basic gene expression. Due to its highly dynamic nature the structure of the spliceosome has remained elusive until now. Research by Kiyoshi Nagai’s group, in the LMB’s Structural Studies Division, has for the first time captured the…
Researchers in Greg Jefferis’s group in the LMB’s Neurobiology Division have developed a new online tool to analyse images of neurons. This tool, known as NBLAST, is free and available to all. NBLAST enables researchers to measure the similarity between neurons and organise them into neuron families, akin to tools such as BLAST that allow…
- LMB CamAWiSE annual ‘What next for your career in science’ event
The LMB and CambridgeAWiSE recently held their 10th annual ‘What next for your career in […]
- LMB welcomes Joseph Yeeles as new Group Leader
The LMB is delighted to announce the arrival of Joseph Yeeles to the LMB’s PNAC […]
- Visualizing and Quantifying Intracellular Behavior and Abundance of the Core Circadian Clock Protein PERIOD2.
Smyllie, NJ., et al.
Curr. Biol. 26(14): 1880-1886. (25th July 2016)
- Crystal Structure of a Group I Energy Coupling Factor Vitamin Transporter S Component in Complex with Its Cognate Substrate.
Josts, I., Almeida Hernandez, Y., Andreeva, A., Tidow, H.
Cell Chem Biol 23(7): 827-36. (21st July 2016)
- Tagging and Enriching Proteins Enables Cell-Specific Proteomics.
Elliott, TS., Bianco, A., Townsley, FM., Fried, SD., Chin, JW.
Cell Chem Biol 23(7): 805-15. (21st July 2016)
- The Molecular Basis for Ubiquitin and Ubiquitin-like Specificities in Bacterial Effector Proteases.
Pruneda, JN., Durkin, CH., Geurink, PP., Ovaa, H., Santhanam, B., Holden, DW., Komander, D.
Mol. Cell 63(2): 261-76. (21st July 2016)
- Dopamine helps worms deal with stress.
Chew, YL., Schafer, WR.
EMBO J. [Epub ahead of print]. (20th July 2016)
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