About us

The LMB is responsible for many pioneering techniques, such as methods for determining the three-dimensional structures of proteins and other macromolecules, the sequencing of DNA and the development of monoclonal antibodies.

Our scientists tackle difficult, long-term research problems. At the same time they are encouraged to exploit their discoveries – through patents, licensing and business start-ups – helping to advance medical research and improve the UK’s economic competitiveness.

Insight on research

mRNA on the move – localisation can affect cell signalling and regulation

Madan - mRNA On The Move

New research from Madan Babu’s group in the LMB’s Structural Studies Division, in collaboration with Toby Gibson from the European Molecular Biology Laboratory in Heidelberg, has shown that the targeted movement of mRNA molecules to allow proteins to be synthesised in specific locations has important implications in cell signalling and development. Proteins have many different []

The mother’s role in protecting the fetal genome from aldehyde damage is revealed.

KJ Patel - Foetal Aldehyde Damage

Whilst a mother’s metabolism provides essential nutrients to enable embryonic development, both mother and embryo can also produce reactive metabolites that can damage DNA. Research undertaken by Nina Oberbeck in KJ Patel’s group, in the LMB’s PNAC Division, has uncovered how the embryo is protected from these genotoxins. Birth defects are common and are a []

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