The LMB is responsible for many pioneering techniques, such as methods for determining the three-dimensional structures of proteins and other macromolecules, the sequencing of DNA and the development of monoclonal antibodies.
Our scientists tackle difficult, long-term research problems. At the same time they are encouraged to exploit their discoveries – through patents, licensing and business start-ups – helping to advance medical research and improve the UK’s economic competitiveness.
The latest advances in cryo electron microscopy have enabled Sjors Scheres’ group, from the LMB’s Structural Studies Division, together with collaborators from Beijing in China, to solve the structure of human gamma-secretase, a membrane protein complex that has an important role in Alzheimer’s disease. Gamma-secretase is made up of four different proteins which are all […]
A cross divisional collaboration at the LMB between the groups of Simon Bullock, in Cell Biology, and Andrew Carter, in Structural Studies, has provided new insight into the activation of the large molecular motor dynein, a critical component of the transport system that operates within cells. The cells within living organisms contain an elaborate transport […]
- LMB Alumni from around the world reunited for 2 day Symposium
The LMB welcomed nearly 600 of its alumni back to a two-day symposium, ‘Molecular Biology […]
- Crystal Growing Competition: Winning schools visit the LMB
Each year, pupils from all over the East of England compete to grow the best […]
- 2014 Milstein Lecture to be given by Peter Walter
Professor Peter Walter will give the 2014 Milstein Lecture on Monday 30 June 2014 at […]
- What next after Academia? Three ways to forge a career away from the bench
A recent event held at the LMB showed how a PhD in science can lead […]
- Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation.
Dingler, FA., Kemmerich, K., Neuberger, MS., Rada, C.
Eur. J. Immunol. 44(7): 1925-35. (27th July 2014)
- Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders.
Blanco, S., et al.
EMBO J. [Epub ahead of print]. (25th July 2014)
- Mechanosensory molecules and circuits in C. elegans.
Pflugers Arch. [Epub ahead of print]. (23rd July 2014)
- Pathway of binding of the intrinsically disordered mitochondrial inhibitor protein to F1-ATPase.
Bason, JV., Montgomery, MG., Leslie, AG., Walker, JE.
Proc. Natl. Acad. Sci. U.S.A. [Epub ahead of print]. (21st July 2014)
- Molecular architecture and mechanism of the anaphase-promoting complex.
Chang, L., Zhang, Z., Yang, J., McLaughlin, SH., Barford, D.
Nature [Epub ahead of print]. (20th July 2014)
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