We are now accepting applications for PhD Studentships starting in 2015/16.
Application deadline is 2nd December 2014 (UK, EU and overseas applicants). Apply Now!
The LMB is responsible for many pioneering techniques, such as methods for determining the three-dimensional structures of proteins and other macromolecules, the sequencing of DNA and the development of monoclonal antibodies.
Our scientists tackle difficult, long-term research problems. At the same time they are encouraged to exploit their discoveries – through patents, licensing and business start-ups – helping to advance medical research and improve the UK’s economic competitiveness.
An unexpected finding from Julian Sale’s group in the LMB’s PNAC Division has revealed that a specialised histone protein called H3.3 is needed for packaging UV-damaged DNA during replication. Use of this histone may act as a flag to help the cell find and repair the damage once replication has been completed, potentially reducing the…
Research from the LMB’s PNAC Division has revealed a new mechanism that cells use to fight infection. Jerry Tam and other members of Leo James’s group have discovered that the protein complement C3, which covalently labels viruses and bacteria in the bloodstream, activates a potent immune response upon cell invasion. Molecular biologists chemically modify proteins…
- Awards for “Imagining the Brain” art winners
Winning students in the LMB’s “Imagining the Brain” competition recently attended an awards ceremony at an […]
- LMB finalist in BIFM Awards 2014
Representatives from the LMB attended a glittering ceremony, hosted by comic and actor Hugh Dennis, […]
- Science Image Award winners announced
The winners of an LMB competition designed to inspire young children about the microscopic world […]
- 2014 Francis Crick Lecture to be given by Stephen J. Elledge
Stephen J. Elledge, Gregor Mendel Professor of Genetics, Department of Genetics, Harvard Medical School will […]
- Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly.
Price, AJ., et al.
PLoS Pathog. 10(10): e1004459. (30th October 2014)
- Class IIa histone deacetylases are conserved regulators of circadian function.
Fogg, PC., et al.
J. Biol. Chem. [Epub ahead of print]. (30th October 2014)
- Cezanne (OTUD7B) regulates HIF-1α homeostasis in a proteasome-independent manner.
Bremm, A., Moniz, S., Mader, J., Rocha, S., Komander, D.
EMBO Rep. [Epub ahead of print]. (29th October 2014)
- Conformation-independent structural comparison of macromolecules with ProSMART.
Nicholls, RA., Fischer, M., McNicholas, S., Murshudov, GN.
Acta Crystallogr. D Biol. Crystallogr. 70(Pt 9): 2487-99. (29th October 2014)
- Efficient Multisite Unnatural Amino Acid Incorporation in Mammalian Cells via Optimized Pyrrolysyl tRNA Synthetase/tRNA Expression and Engineered eRF1.
Schmied, WH., Elsässer, SJ., Uttamapinant, C., Chin, JW.
J. Am. Chem. Soc. [Epub ahead of print]. (28th October 2014)
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