The LMB is responsible for many pioneering techniques, such as methods for determining the three-dimensional structures of proteins and other macromolecules, the sequencing of DNA and the development of monoclonal antibodies.
Our scientists tackle difficult, long-term research problems. At the same time they are encouraged to exploit their discoveries – through patents, licensing and business start-ups – helping to advance medical research and improve the UK’s economic competitiveness.
New research from Madan Babu’s group in the LMB’s Structural Studies Division, in collaboration with Toby Gibson from the European Molecular Biology Laboratory in Heidelberg, has shown that the targeted movement of mRNA molecules to allow proteins to be synthesised in specific locations has important implications in cell signalling and development. Proteins have many different […]
Whilst a mother’s metabolism provides essential nutrients to enable embryonic development, both mother and embryo can also produce reactive metabolites that can damage DNA. Research undertaken by Nina Oberbeck in KJ Patel’s group, in the LMB’s PNAC Division, has uncovered how the embryo is protected from these genotoxins. Birth defects are common and are a […]
- Protein Synthesis Technology developed at the LMB licenced for use in drug discovery
A method for linking proteins together with specific chemical bonds, developed in the LMB’s PNAC […]
- John Sutherland awarded the 2014 Royal Society Darwin Medal
John Sutherland, from the LMB’s Protein and Nucleic Acid Chemistry Division, has been awarded the […]
- LMB Alumni from around the world reunited for 2 day Symposium
The LMB welcomed nearly 600 of its alumni back to a two-day symposium, ‘Molecular Biology […]
- Crystal Growing Competition: Winning schools visit the LMB
Each year, pupils from all over the East of England compete to grow the best […]
- Ultrafast tissue staining with chemical tags.
Kohl, J., et al.
Proc. Natl. Acad. Sci. U.S.A. [Epub ahead of print]. (25th August 2014)
- Asymmetric mRNA localization contributes to fidelity and sensitivity of spatially localized systems.
Weatheritt, RJ., Gibson, TJ., Babu, MM.
Nat. Struct. Mol. Biol. [Epub ahead of print]. (24th August 2014)
- A molecular mechanism of mitotic centrosome assembly in Drosophila.
Conduit, PT., et al.
Elife : e03399 [Epub ahead of print]. (22nd August 2014)
- An inducible chaperone adapts proteasome assembly to stress.
Hanssum, A., Zhong, Z., Rousseau, A., Krzyzosiak, A., Sigurdardottir, A., Bertolotti, A.
Mol. Cell 55(4): 566-77. (21st August 2014)
- Rbfox2-Coordinated Alternative Splicing of Mef2d and Rock2 Controls Myoblast Fusion during Myogenesis.
Singh, RK., Xia, Z., Bland, CS., Kalsotra, A., Scavuzzo, MA., Curk, T., Ule, J., Li, W., Cooper, TA.
Mol. Cell 55(4): 592-603. (21st August 2014)
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