The LMB is responsible for many pioneering techniques, such as methods for determining the three-dimensional structures of proteins and other macromolecules, the sequencing of DNA and the development of monoclonal antibodies.
Our scientists tackle difficult, long-term research problems. At the same time they are encouraged to exploit their discoveries – through patents, licensing and business start-ups – helping to advance medical research and improve the UK’s economic competitiveness.
Small molecules are often used to regulate the functions of proteins and provide many drugs and tools for understanding biological pathways. However, selectively controlling a specific target protein within living cells is a major challenge. Jason Chin’s group from the LMB’s PNAC Division have created a new technique called BOLT that can selectively regulate specific…
There is compelling evidence that in the distant past, our single-celled ancestors used RNA, a chemical cousin of DNA, for both genetic information storage and metabolism. This primordial “RNA world” would have needed an RNA enzyme able to replicate itself and other primordial “RNA genes”. However, it is not known how such a complex function…
- Simon Bullock and Philipp Holliger elected to EMBO membership
Two LMB group leaders, Simon Bullock from the Cell Biology Division and Philipp Holliger from […]
- KJ Patel elected Fellow of the Royal Society
KJ Patel, group leader in the LMB’s PNAC Division, has been elected as a Fellow […]
- LMB welcomes two new group leaders: Rebecca Taylor and Wanda Kukulski
The LMB is delighted to announce the recent arrival of two new group leaders: Rebecca […]
- Golden grids for electron microscopy licensed by Quantifoil
New specimen support grids for electron microscopy, made of pure gold and designed by Lori […]
- The homo-oligomerisation of both Sas-6 and Ana2 is required for efficient centriole assembly in flies.
Cottee, MA., Muschalik, N., Johnson, S., Leveson, J., Raff, JW., Lea, SM.
Elife 4 [Epub ahead of print]. (23rd May 2015)
- Innate lymphoid cells. Innate lymphoid cells: a new paradigm in immunology.
Eberl, G., Colonna, M., Di Santo, JP., McKenzie, AN.
Science 348(6237): aaa6566. (22nd May 2015)
- Cryo-EM: A Unique Tool for the Visualization of Macromolecular Complexity.
Nogales, E., Scheres, SH.
Mol. Cell 58(4): 677-689. (21st May 2015)
- Recursive splicing in long vertebrate genes.
Sibley, CR., et al.
Nature 521(7552): 371-5. (21st May 2015)
- A Multilaboratory Comparison of Calibration Accuracy and the Performance of External References in Analytical Ultracentrifugation.
Zhao, H., et al.
PLoS ONE 10(5): e0126420. (21st May 2015)
See more Publications