The MRC Laboratory of Molecular Biology (LMB) is a research institute dedicated to the understanding of important biological processes at the levels of atoms, molecules, cells and organisms. In doing so, we provide knowledge needed to solve key problems in human health.
Our scientists tackle fundamental, often difficult and long-term research problems. The LMB has made revolutionary contributions to science, such as pioneering X-ray crystallography to determine protein structures, the sequencing of DNA and the development of monoclonal antibodies. Ten Nobel Prizes have been awarded for work carried out by LMB scientists.
The LMB also promotes the application and exploitation of our research findings, both by collaboration with existing companies and the founding of new ones, helping to advance medical research and the translation and application of knowledge.
The LMB provides an unsurpassed environment for both young and established researchers, with state-of-the-art facilities and a unique scientific culture. The LMB has always been very diverse, with a truly international outlook. We currently employ men and women from over 50 countries, and LMB alumni work in research organisations across the world.
Neural networks, circuits of neurons, are emerging as the fundamental computational unit of the brain and it is becoming progressively clearer that neural network dysfunction is at the core of a number of psychiatric and neurodegenerative disorders. Yet our ability to target…
Alzheimer’s disease, the most common neurodegenerative disease, is characterised by the formation of filamentous Tau protein inside nerve cells and amyloid-beta peptides outside cells. Despite more than three decades of research into Tau filaments from a range of different neurodegenerative diseases, atomic…
- LMB welcomes over 2000 visitors to a fun-packed Open Day
On Saturday 17th June the LMB held a spectacular Open Day as part of the […]
- Sjors Scheres elected to EMBO membership
Sjors Scheres, a Group Leader in the LMB’s Structural Studies Division, has been elected as […]
- Automated and controlled mechanical stimulation and functional imaging in vivo in C. elegans.
Cho, Y., Porto, DA., Hwang, H., Grundy, LJ., Schafer, WR., Lu, H.
Lab Chip 17(15): 2609-2618. (25th July 2017)
- Efficient Delivery of Quantum Dots into the Cytosol of Cells Using Cell-Penetrating Poly(disulfide)s.
Derivery, E., Bartolami, E., Matile, S., Gonzalez-Gaitan, M.
J. Am. Chem. Soc. [Epub ahead of print]. (25th July 2017)
- An extended model of vesicle fusion at the plasma membrane to estimate protein lateral diffusion from TIRF microscopy images.
Basset, A., Bouthemy, P., Boulanger, J., Waharte, F., Salamero, J., Kervrann, C.
BMC Bioinformatics 18(1): 352. (24th July 2017)
- High Energy Radical Chemistry Formation of HCN-rich Atmospheres on early Earth.
Ferus, M., Kubelík, P., Knížek, A., Pastorek, A., Sutherland, J., Civiš, S.
Sci Rep 7(1): 6275. (24th July 2017)
- Efficient 3D-CTF correction for cryo-electron tomography using NovaCTF improves subtomogram averaging resolution to 3.4 Å.
Turoňová, B., Schur, FKM., Wan, W., Briggs, JAG.
J. Struct. Biol. [Epub ahead of print]. (22nd July 2017)
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