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The LMB is responsible for many pioneering techniques, such as methods for determining the three-dimensional structures of proteins and other macromolecules, the sequencing of DNA and the development of monoclonal antibodies.
Our scientists tackle difficult, long-term research problems. At the same time they are encouraged to exploit their discoveries – through patents, licensing and business start-ups – helping to advance medical research and improve the UK’s economic competitiveness.
The design and synthesis of genomes provides a powerful approach for understanding and engineering biology. The development of methods that can accurately replace the genome in sections, provide feedback on precisely where a given design fails and on how to repair it, and that can be rapidly repeated for whole genome replacement would accelerate our…
The ubiquitin system is a complex system in all eukaryotic organisms involved in the regulation of most cellular processes. A huge variety of signals are assembled with ubiquitin molecules onto cellular proteins to mark them for a specific task. Important regulators of the ubiquitin system are deubiquitinating enzymes (DUBs), which remove, or cleave, ubiquitin chains…
- LMB rides to victory in National Cycle Challenge
The LMB has continued its winning cycling record by taking first place in its category […]
- John O’Neill receives EMBO Young Investigator Programme Award
LMB group leader, John O’Neill, has been elected into the 2016 EMBO Young Investigator Programme. […]
- Crystal Structure of Glycoprotein C from a Hantavirus in the Post-fusion Conformation.
Willensky, S., Bar-Rogovsky, H., Bignon, EA., Tischler, ND., Modis, Y., Dessau, M.
PLoS Pathog. 12(10): e1005948. (26th October 2016)
- The ordered assembly of tau is the gain-of-toxic function that causes human tauopathies.
Alzheimers Dement 12(10): 1040-1050. (26th October 2016)
- The Phosphatase Dusp7 Drives Meiotic Resumption and Chromosome Alignment in Mouse Oocytes.
Tischer, T., Schuh, M.
Cell Rep 17(5): 1426-1437. (25th October 2016)
- Nematode nervous systems.
Curr. Biol. 26(20): R955-R959. (24th October 2016)
- Myosins: Domain Organisation, Motor Properties, Physiological Roles and Cellular Functions.
Masters, TA., Kendrick-Jones, J., Buss, F.
Handb Exp Pharmacol [Epub ahead of print]. (19th October 2016)
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