We are now accepting applications for PhD Studentships starting in 2016/17.
Application deadline is the 2nd December 2015 (UK, EU and overseas applicants). Apply Now!
The LMB is responsible for many pioneering techniques, such as methods for determining the three-dimensional structures of proteins and other macromolecules, the sequencing of DNA and the development of monoclonal antibodies.
Our scientists tackle difficult, long-term research problems. At the same time they are encouraged to exploit their discoveries – through patents, licensing and business start-ups – helping to advance medical research and improve the UK’s economic competitiveness.
The process of autophagy, in which unnecessary or dysfunctional cellular components are degraded, is important to prevent accumulation of cellular waste and can be triggered by cellular stress. Roger Williams’ group, in the LMB’s PNAC Division, in collaboration with Nicholas Ktistakis at Cambridge’s Babraham Institute and Jan Steyaert at the Brussels VIB Structural Biology Research…
Formaldehyde, or formalin, is well known to all of us as a common chemical used in many industrial processes and also as a preservative, remarkably we also produce formaldehyde in our bodies. This “endogenous” formaldehyde is ubiquitous, and sufficient amounts might be produced that could damage our cells. Work by Lucas Pontel and Ivan Rosado…
- LMB supports county-wide STOP Suicide campaign
The LMB has strengthened its commitment to supporting the mental wellbeing of its staff and […]
- LMB HR raise £194 at Macmillan Coffee Morning
The HR team at the LMB had to hone their baking skills in preparation for […]
- The Autophagy Receptor TAX1BP1 and the Molecular Motor Myosin VI Are Required for Clearance of Salmonella Typhimurium by Autophagy.
Tumbarello, DA., Manna, PT., Allen, M., Bycroft, M., Arden, SD., Kendrick-Jones, J., Buss, F.
PLoS Pathog. 11(10): e1005174. (9th October 2015)
- Atomic-Resolution Structures of the APC/C Subunits Apc4 and the Apc5 N-Terminal Domain.
Cronin, NB., Yang, J., Zhang, Z., Kulkarni, K., Chang, L., Yamano, H., Barford, D.
J. Mol. Biol. 427(20): 3300-15. (9th October 2015)
- Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes.
Rostislavleva, K., et al.
Science 350(6257): aac7365. (9th October 2015)
- Pregnancy, Primary Aldosteronism, and Adrenal CTNNB1 Mutations.
Teo, AE., et al.
N. Engl. J. Med. 373(15): 1429-36. (8th October 2015)
- Efficient APC/C substrate degradation in cells undergoing mitotic exit depends on K11 ubiquitin linkages.
Min, M., Mevissen, TE., De Luca, M., Komander, D., Lindon, C.
Mol. Biol. Cell [Epub ahead of print]. (7th October 2015)
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