The LMB is responsible for many pioneering techniques, such as methods for determining the three-dimensional structures of proteins and other macromolecules, the sequencing of DNA and the development of monoclonal antibodies.
Our scientists tackle difficult, long-term research problems. At the same time they are encouraged to exploit their discoveries – through patents, licensing and business start-ups – helping to advance medical research and improve the UK’s economic competitiveness.
Our cycle of sleep and wakefulness is controlled by a daily (circadian) body clock in our brain. When this cycle happens in a regular way people function well, but when this cycle is disturbed it can lead to a severely disrupted life. The suprachiasmatic nucleus (SCN) is part of the body clock and individual neurons of […]
New research, from a team of scientists in the LMB’s Structural Studies Division and the Texas A&M Health Science Center, illustrates the molecular mechanism behind a fundamental cellular process. The research, published in PNAS, provides new insights into the way in which components of the nuclear protein transport machinery move through nuclear pores. Nuclear pores […]
- KJ Patel elected Fellow of the UK Academy of Medical Sciences
KJ Patel, group leader in the LMB’s Protein and Nucleic Acid Chemistry Division, has been […]
- Michael Neuberger elected a Foreign Associate of the US National Academy of Sciences
Dr Michael Neuberger, group leader in the LMB’s Protein and Nucleic Acid Chemistry, has been […]
- DNA 60th Anniversary celebrated at Cambridge
On the 25th April 1953, Francis Crick and Jim Watson published their groundbreaking paper in […]
- Ari Helenius to deliver 2013 Max Perutz lecture
This year’s Max Perutz lecture on “Five ways for viruses to enter the animal cell” […]
- Prebiotically plausible oligoribonucleotide ligation facilitated by chemoselective acetylation.
Bowler, FR., Chan, CK., Duffy, CD., Gerland, B., Islam, S., Powner, MW., Sutherland, JD., Xu, J.
Nat Chem 5(5): 383-9. (14th May 2013)
- A structural role for the PHP domain in E. coli DNA polymerase III.
Barros, T., et al.
BMC Struct. Biol. 13(1): 8 [Epub ahead of print]. (14th May 2013)
- Connecting with an old partner in a new way.
Burke, JE., Williams, RL.
Cancer Cell 23(5): 559-61. (13th May 2013)
- Cellular self-defense: how cell-autonomous immunity protects against pathogens.
Randow, F., MacMicking, JD., James, LC.
Science 340(6133): 701-6. (10th May 2013)
- Biophysical Fragment Screening of the β1-Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design.
Christopher, JA., et al.
J. Med. Chem. 56(9): 3446-55. (9th May 2013)
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