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About us

The LMB is responsible for many pioneering techniques, such as methods for determining the three-dimensional structures of proteins and other macromolecules, the sequencing of DNA and the development of monoclonal antibodies.

Our scientists tackle difficult, long-term research problems. At the same time they are encouraged to exploit their discoveries – through patents, licensing and business start-ups – helping to advance medical research and improve the UK’s economic competitiveness.

Insight on research

Structure of the endosomal Vps34 complex II reveals insights into its function


The process of autophagy, in which unnecessary or dysfunctional cellular components are degraded, is important to prevent accumulation of cellular waste and can be triggered by cellular stress. Roger Williams’ group, in the LMB’s PNAC Division, in collaboration with Nicholas Ktistakis at Cambridge’s Babraham Institute and Jan Steyaert at the Brussels VIB Structural Biology Research…

A fundamental protection mechanism against formalin in mammals is revealed

Molecular Cell Cover

Formaldehyde, or formalin, is well known to all of us as a common chemical used in many industrial processes and also as a preservative, remarkably we also produce formaldehyde in our bodies. This “endogenous” formaldehyde is ubiquitous, and sufficient amounts might be produced that could damage our cells. Work by Lucas Pontel and Ivan Rosado…

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Latest publications

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