About us
The LMB is responsible for many pioneering techniques, such as methods for determining the three-dimensional structures of proteins and other macromolecules, the sequencing of DNA and the development of monoclonal antibodies.
Our scientists tackle difficult, long-term research problems. At the same time they are encouraged to exploit their discoveries – through patents, licensing and business start-ups – helping to advance medical research and improve the UK’s economic competitiveness.
Quick links
Insight on research
New mechanism in the body’s timekeeping revealed
Our cycle of sleep and wakefulness is controlled by a daily (circadian) body clock in our brain. When this cycle happens in a regular way people function well, but when this cycle is disturbed it can lead to a severely disrupted life. The suprachiasmatic nucleus (SCN) is part of the body clock and individual neurons of […]
Understanding the mechanism of the nucleocytoplasmic transport cycle
New research, from a team of scientists in the LMB’s Structural Studies Division and the Texas A&M Health Science Center, illustrates the molecular mechanism behind a fundamental cellular process. The research, published in PNAS, provides new insights into the way in which components of the nuclear protein transport machinery move through nuclear pores. Nuclear pores […]
Latest news
KJ Patel elected Fellow of the UK Academy of Medical SciencesKJ Patel, group leader in the LMB’s Protein and Nucleic Acid Chemistry Division, has been […]
Michael Neuberger elected a Foreign Associate of the US National Academy of SciencesDr Michael Neuberger, group leader in the LMB’s Protein and Nucleic Acid Chemistry, has been […]
DNA 60th Anniversary celebrated at CambridgeOn the 25th April 1953, Francis Crick and Jim Watson published their groundbreaking paper in […]
Ari Helenius to deliver 2013 Max Perutz lectureThis year’s Max Perutz lecture on “Five ways for viruses to enter the animal cell” […]
Latest publications
- Prebiotically plausible oligoribonucleotide ligation facilitated by chemoselective acetylation.
Bowler, FR., Chan, CK., Duffy, CD., Gerland, B., Islam, S., Powner, MW., Sutherland, JD., Xu, J.
Nat Chem 5(5): 383-9. (14th May 2013) - A structural role for the PHP domain in E. coli DNA polymerase III.
Barros, T., et al.
BMC Struct. Biol. 13(1): 8 [Epub ahead of print]. (14th May 2013) - Connecting with an old partner in a new way.
Burke, JE., Williams, RL.
Cancer Cell 23(5): 559-61. (13th May 2013) - Cellular self-defense: how cell-autonomous immunity protects against pathogens.
Randow, F., MacMicking, JD., James, LC.
Science 340(6133): 701-6. (10th May 2013) - Biophysical Fragment Screening of the β1-Adrenergic Receptor: Identification of High Affinity Arylpiperazine Leads Using Structure-Based Drug Design.
Christopher, JA., et al.
J. Med. Chem. 56(9): 3446-55. (9th May 2013)
See more Publications