About us

The LMB is responsible for many pioneering techniques, such as methods for determining the three-dimensional structures of proteins and other macromolecules, the sequencing of DNA and the development of monoclonal antibodies.

Our scientists tackle difficult, long-term research problems. At the same time they are encouraged to exploit their discoveries – through patents, licensing and business start-ups – helping to advance medical research and improve the UK’s economic competitiveness.

Insight on research

Golden grids for electron cryo-microscopy


Recent exciting advances in electron cryo-microscopy (cryo-EM) have allowed scientists to find very detailed structures of some proteins. Still, determining the structure of many proteins remains too difficult for cryo-EM, as the images are too noisy to use for structure determination. Lori Passmore and Chris Russo from the LMB’s Structural Studies Division have designed new…

Signposts for organelle identity – new Rab GTPase effectors found


Cells contain specialised membrane-bound compartments called organelles, which are vital to the cell as they allow it to separate different biochemical reactions that otherwise might interfere with each other. To function correctly, these intracellular compartments need to recruit proteins from the cytoplasm, and since every organelle has a specific role, each one needs a particular…

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