We are now accepting applications for PhD Studentships starting in 2016/17.
Application deadline is the 2nd December 2015 (UK, EU and overseas applicants). Apply Now!
The LMB is responsible for many pioneering techniques, such as methods for determining the three-dimensional structures of proteins and other macromolecules, the sequencing of DNA and the development of monoclonal antibodies.
Our scientists tackle difficult, long-term research problems. At the same time they are encouraged to exploit their discoveries – through patents, licensing and business start-ups – helping to advance medical research and improve the UK’s economic competitiveness.
Detecting and signalling DNA single-strand breaks: understanding the mechanisms of DNA damage recognition
DNA damage represents a constant threat to the integrity of genomic information in cells and is closely linked to the origins of cancer. DNA single-strand breaks (SSBs) are the most frequent type of damage with thousands of such lesions from different sources occurring in each cell every day. Despite many advances in understanding the mechanistic…
Ribosomes, the molecular machines in cells that make proteins, are constructed in a series of discrete steps to create both a large and a small subunit. Release of a key building block, eIF6, from the large 60S subunit allows assembly of the mature active ribosome. Alan Warren’s group, at the University of Cambridge, in collaboration…
- “Gifted and Talented” sixth-formers visit LMB for degree-level practicals
26 AS-level students on an intensive week of “Biology and Genetics for Gifted and Talented […]
- DNA sculpture from CRUK Art Trail finds home in Francis Crick’s former Laboratory
During the summer of 2015 Cancer Research UK launched a DNA inspired art trail across […]
- Thon rings from amorphous ice and implications of beam-induced Brownian motion in single particle electron cryo-microscopy.
G McMullan, ., Vinothkumar, KR., Henderson, R.
Ultramicroscopy 158: 26-32. (27th November 2015)
- EGF-dependent re-routing of vesicular recycling switches spontaneous phosphorylation suppression to EGFR signaling.
Baumdick, M., et al.
Elife 4 [Epub ahead of print]. (26th November 2015)
- Identification of novel, therapy-responsive protein biomarkers in a mouse model of Duchenne muscular dystrophy by aptamer-based serum proteomics.
Coenen-Stass, AM., et al.
Sci Rep 5: 17014. (23rd November 2015)
- Reducing Lissencephaly-1 levels augments mitochondrial transport and has a protective effect in adult Drosophila neurons.
Vagnoni, A., Hoffmann, PC., Bullock, SL.
J. Cell. Sci. [Epub ahead of print]. (23rd November 2015)
- Sequence-specific (1)H, (13)C and (15)N backbone resonance assignments of the plakin repeat domain of human envoplakin.
Jeeves, M., Fogl, C., Al-Jassar, C., Chidgey, M., Overduin, M.
Biomol NMR Assign [Epub ahead of print]. (21st November 2015)
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