The MRC Laboratory of Molecular Biology (LMB) is a research institute dedicated to the understanding of important biological processes at the levels of atoms, molecules, cells and organisms. In doing so, we provide knowledge needed to solve key problems in human health.
Our scientists tackle fundamental, often difficult and long-term research problems. The LMB has made revolutionary contributions to science, such as pioneering X-ray crystallography to determine protein structures, the sequencing of DNA and the development of monoclonal antibodies. Ten Nobel Prizes have been awarded for work carried out by LMB scientists.
The LMB also promotes the application and exploitation of our research findings, both by collaboration with existing companies and the founding of new ones, helping to advance medical research and the translation and application of knowledge.
The LMB provides an unsurpassed environment for both young and established researchers, with state-of-the-art facilities and a unique scientific culture. The LMB has always been very diverse, with a truly international outlook. We currently employ men and women from over 50 countries, and LMB alumni work in research organisations across the world.
Cell growth requires the synthesis of molecules, such as nucleotides to make DNA and amino acids to make proteins. One essential building block of these is the one carbon unit. This is produced by the one carbon (1C) cycle, which requires the…
Amino acids are the building blocks of proteins. Just twenty different amino acids are strung together in different orders – like beads – to build all the proteins in living organisms. When a single type of amino acid is found consecutively within…
- 2017 Francis Crick Lecture to be given by Jack Szostak
Jack Szostak will give the 2017 Francs Crick Lecture on Thursday 7th September at 4pm […]
- International young, budding scientists visit the LMB
The LMB recently hosted eighteen students from the London International Youth Science Forum (LIYSF) for […]
- Exploring the Sequence-based Prediction of Folding Initiation Sites in Proteins.
Raimondi, D., Orlando, G., Pancsa, R., Khan, T., Vranken, WF.
Sci Rep 7(1): 8826. (18th August 2017)
- An overview of hydrogen deuterium exchange mass spectrometry (HDX-MS) in drug discovery.
Masson, GR., Jenkins, ML., Burke, JE.
Expert Opin Drug Discov : 1-14 [Epub ahead of print]. (17th August 2017)
- Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells.
Rauber, S., et al.
Nat. Med. 23(8): 938-944. (17th August 2017)
- Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism.
Burgos-Barragan, G., et al.
Nature [Epub ahead of print]. (16th August 2017)
- Structural Mechanism for Modulation of Synaptic Neuroligin-Neurexin Signaling by MDGA Proteins.
Elegheert, J., et al.
Neuron 95(4): 896-913.e10. (16th August 2017)
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