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* [[Prepare input files]] | * [[Prepare input files]] | ||
* [[Calculate 2D class averages]] | * [[Calculate 2D class averages]] | ||
* [[Classify structural heterogeneity | * [[Classify 3D structural heterogeneity]] | ||
* [[Refine a structure to high-resolution]] | * [[Refine a structure to high-resolution]] | ||
Revision as of 14:01, 28 September 2011
RELION
RELION (for REgularised LIkelihood OptimisatioN) is a stand-alone computer program for Maximum A Posteriori refinement of (multiple) 3D reconstructions or 2D class averages in cryo-electron microscopy. It is developed in the research group of Sjors Scheres at the MRC Laboratory of Molecular Biology. The underlying theory of MAP refinement is given in Scheres (2011). If RELION is useful in your work, please cite this paper.