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RELION (for REgularised LIkelihood OptimisatioN) is a stand-alone computer program for Maximum A Posteriori refinement of (multiple) 3D reconstructions or 2D class averages in cryo-electron microscopy. It is developed by the research group of [http://www2.mrc-lmb.cam.ac.uk/groups/scheres/ Sjors Scheres] at the [http://www2.mrc-lmb.cam.ac.uk MRC Laboratory of Molecular Biology]. The underlying theory of MAP refinement is given in Scheres (2011), submitted. If RELION is useful in your work, please cite this paper! Thank you. | RELION (for REgularised LIkelihood OptimisatioN) is a stand-alone computer program for Maximum A Posteriori refinement of (multiple) 3D reconstructions or 2D class averages in cryo-electron microscopy. It is developed by the research group of [http://www2.mrc-lmb.cam.ac.uk/groups/scheres/ Sjors Scheres] at the [http://www2.mrc-lmb.cam.ac.uk MRC Laboratory of Molecular Biology]. The underlying theory of MAP refinement is given in Scheres (2011), submitted. If RELION is useful in your work, please cite this paper! Thank you. | ||
Revision as of 17:17, 27 September 2011
RELION (for REgularised LIkelihood OptimisatioN) is a stand-alone computer program for Maximum A Posteriori refinement of (multiple) 3D reconstructions or 2D class averages in cryo-electron microscopy. It is developed by the research group of Sjors Scheres at the MRC Laboratory of Molecular Biology. The underlying theory of MAP refinement is given in Scheres (2011), submitted. If RELION is useful in your work, please cite this paper! Thank you.
Getting started
How To
- Preprocess my data
- Prepare input STAR files
- Calculate 2D class averages
- Classify structural heterogeneity in 3D
- Refine a structure to high-resolution
WIKI: Getting started
Consult the User's Guide for information on using the wiki software.