Relion:About

RELION (for REgularised LIkelihood OptimisatioN) is a stand-alone computer program for Maximum A Posteriori refinement of (multiple) 3D reconstructions or 2D class averages in cryo-electron microscopy. It is developed by the research group of Sjors Scheres at the [[1][MRC Laboratory of Molecular Biology]]. The underlying theory of MAP refinement is given in Scheres (2011), submitted. If RELION is useful in your work, please cite this paper! Thank you.