Pubmed articles are listed below. For preprints and other contributions, please see Tanmay Bharat’s Google Scholar page.
2022
- Krause, S., Gfrerer, S., von Kügelgen, A., Reuse, C., Dombrowski, N., Villanueva, L., Bunk, B., Spröer, C., Neu, T.R., Kuhlicke, U., Schmidt-Hohagen, K., Hiller, K., Bharat, T.A.M., Rachel, R., Spang, A., Gescher, J. (2022 )
The importance of biofilm formation for cultivation of a Micrarchaeon and its interactions with its Thermoplasmatales host.
Nat Commun 13(1): 1735 - Böhning, J., Bharat, T.A.M., Collins, S.M. (2022 )
Compressed sensing for electron cryotomography and high-resolution subtomogram averaging of biological specimens.
Structure 30(3): 408-417.e4 - Herdman, M., von Kügelgen, A., Kureisaite-Ciziene, D., Duman, R., El Omari, K., Garman, E.F., Kjaer, A., Kolokouris, D., Löwe, J., Wagner, A., Stansfeld, P.J., Bharat, T.A.M. (2022 )
High-resolution mapping of metal ions reveals principles of surface layer assembly in Caulobacter crescentus cells.
Structure 30(2): 215-228.e5
2021
- von Kügelgen, A., Alva, V., Bharat, T.A.M. (2021 )
Complete atomic structure of a native archaeal cell surface.
Cell Rep 37(8): 110052 - Melia, C.E., Bolla, J.R., Katharios-Lanwermeyer, S., Mihaylov, D.B., Hoffmann, P.C., Huo, J., Wozny, M.R., Elfari, L.M., Böhning, J., Morgan, A.N., Hitchman, C.J., Owens, R.J., Robinson, C.V., O'Toole, G.A., Bharat, T.A.M. (2021 )
Architecture of cell-cell junctions in situ reveals a mechanism for bacterial biofilm inhibition.
Proc Natl Acad Sci U S A 118(31) - Böhning, J., Bharat, T.A.M. (2021)
Impressions of expression: bringing structure to the cell.
Nat Rev Microbiol 19(6): 346 - Bharat, T.A.M., von Kügelgen, A., Alva, V. (2021 )
Molecular Logic of Prokaryotic Surface Layer Structures.
Trends Microbiol 29(5): 405-415 - Böhning, J., Bharat, T.A.M. (2021 )
Towards high-throughput in situ structural biology using electron cryotomography.
Prog Biophys Mol Biol 160: 97-103
2020
- Letham, S.C., Bharat, T.A.M. (2020)
Illuminating the dynamics of biofilms.
Nat Rev Microbiol 18(10): 544 - Djeghloul, D., Patel, B., Kramer, H., Dimond, A., Whilding, C., Brown, K., Kohler, A.C., Feytout, A., Veland, N., Elliott, J., Bharat, T.A.M., Tarafder, A.K., Löwe, J., Ng, B.L., Guo, Y., Guy, J., Huseyin, M.K., Klose, R.J., Merkenschlager, M., Fisher, A.G. (2020 )
Identifying proteins bound to native mitotic ESC chromosomes reveals chromatin repressors are important for compaction.
Nat Commun 11(1): 4118 - Chorev, D.S., Tang, H., Rouse, S.L., Bolla, J.R., von Kügelgen, A., Baker, L.A., Wu, D., Gault, J., Grünewald, K., Bharat, T.A.M., Matthews, S.J., Robinson, C.V. (2020 )
The use of sonicated lipid vesicles for mass spectrometry of membrane protein complexes.
Nat Protoc 15(5): 1690-1706 - Tarafder, A.K., von Kügelgen, A., Mellul, A.J., Schulze, U., Aarts, D.G.A.L., Bharat, T.A.M. (2020 )
Phage liquid crystalline droplets form occlusive sheaths that encapsulate and protect infectious rod-shaped bacteria.
Proc Natl Acad Sci U S A 117(9): 4724-4731 - von Kügelgen, A., Tang, H., Hardy, G.G., Kureisaite-Ciziene, D., Brun, Y.V., Stansfeld, P.J., Robinson, C.V., Bharat, T.A.M. (2020 )
In Situ Structure of an Intact Lipopolysaccharide-Bound Bacterial Surface Layer.
Cell 180(2): 348-358.e15
2019
- Hoffmann, P.C., Bharat, T.A.M., Wozny, M.R., Boulanger, J., Miller, E.A., Kukulski, W. (2019 )
Tricalbins Contribute to Cellular Lipid Flux and Form Curved ER-PM Contacts that Are Bridged by Rod-Shaped Structures.
Dev Cell 51(4): 488-502.e8 - Sulkowski, N.I., Hardy, G.G., Brun, Y.V., Bharat, T.A.M. (2019 )
A Multiprotein Complex Anchors Adhesive Holdfast at the Outer Membrane of Caulobacter crescentus.
J Bacteriol 201(18)
2018
- Melia, C.E., Bharat, T.A.M. (2018 )
Locating macromolecules and determining structures inside bacterial cells using electron cryotomography.
Biochim Biophys Acta Proteins Proteom 1866(9): 973-981 - Bharat, T.A.M., Hoffmann, P.C., Kukulski, W. (2018 )
Correlative Microscopy of Vitreous Sections Provides Insights into BAR-Domain Organization In Situ.
Structure 26(6): 879-886.e3 - Fernandez, J.J., Li, S., Bharat, T.A.M., Agard, D.A. (2018 )
Cryo-tomography tilt-series alignment with consideration of the beam-induced sample motion.
J Struct Biol 202(3): 200-209
2017
- Deng, X., Fink, G., Bharat, T.A.M., He, S., Kureisaite-Ciziene, D., Löwe, J. (2017 )
Four-stranded mini microtubules formed by BtubAB show dynamic instability.
Proc Natl Acad Sci U S A 114(29): E5950-E5958 - Bharat, T.A.M., Kureisaite-Ciziene, D., Hardy, G.G., Yu, E.W., Devant, J.M., Hagen, W.J.H., Brun, Y.V., Briggs, J.A.G., Löwe, J. (2017 )
Structure of the hexagonal surface layer on Caulobacter crescentus cells.
Nat Microbiol 2: 17059
2016
- Bharat, T.A., Scheres, S.H. (2016 )
Resolving macromolecular structures from electron cryo-tomography data using subtomogram averaging in RELION.
Nat Protoc 11(11): 2054-65 - Martin, T.G., Bharat, T.A., Joerger, A.C., Bai, X.C., Praetorius, F., Fersht, A.R., Dietz, H., Scheres, S.H. (2016 )
Design of a molecular support for cryo-EM structure determination.
Proc Natl Acad Sci U S A 113(47): E7456-E7463
2015
- Bharat, T.A.M., Russo, C.J., Löwe, J., Passmore, L.A., Scheres, S.H.W. (2015 )
Advances in Single-Particle Electron Cryomicroscopy Structure Determination applied to Sub-tomogram Averaging.
Structure 23(9): 1743-1753 - Bharat, T.A., Murshudov, G.N., Sachse, C., Löwe, J. (2015 )
Structures of actin-like ParM filaments show architecture of plasmid-segregating spindles.
Nature 523(7558): 106-10 - Fromm, S.A., Bharat, T.A., Jakobi, A.J., Hagen, W.J., Sachse, C. (2015 )
Seeing tobacco mosaic virus through direct electron detectors.
J Struct Biol 189(2): 87-97
2014
- Szwedziak, P., Wang, Q., Bharat, T.A., Tsim, M., Löwe, J. (2014 )
Architecture of the ring formed by the tubulin homologue FtsZ in bacterial cell division.
Elife 3: e04601 - Davey, N.E., Satagopam, V.P., Santiago-Mozos, S., Villacorta-Martin, C., Bharat, T.A., Schneider, R., Briggs, J.A. (2014 )
The HIV mutation browser: a resource for human immunodeficiency virus mutagenesis and polymorphism data.
PLoS Comput Biol 10(12): e1003951 - Bharat, T.A., Castillo Menendez, L.R., Hagen, W.J., Lux, V., Igonet, S., Schorb, M., Schur, F.K., Kräusslich, H.G., Briggs, J.A. (2014 )
Cryo-electron microscopy of tubular arrays of HIV-1 Gag resolves structures essential for immature virus assembly.
Proc Natl Acad Sci U S A 111(22): 8233-8 - van den Ent, F., Izoré, T., Bharat, T.A., Johnson, C.M., Löwe, J. (2014 )
Bacterial actin MreB forms antiparallel double filaments.
Elife 3: e02634 - Bharat, T.A., Malsam, J., Hagen, W.J., Scheutzow, A., Söllner, T.H., Briggs, J.A. (2014 )
SNARE and regulatory proteins induce local membrane protrusions to prime docked vesicles for fast calcium-triggered fusion.
EMBO Rep 15(3): 308-14
2013
- Bharat, T.A., Zbaida, D., Eisenstein, M., Frankenstein, Z., Mehlman, T., Weiner, L., Sorzano, C.O., Barak, Y., Albeck, S., Briggs, J.A., Wolf, S.G., Elbaum, M. (2013 )
Variable internal flexibility characterizes the helical capsid formed by agrobacterium VirE2 protein on single-stranded DNA.
Structure 21(7): 1158-67
2012
- Steringer, J.P., Bleicken, S., Andreas, H., Zacherl, S., Laussmann, M., Temmerman, K., Contreras, F.X., Bharat, T.A., Lechner, J., Müller, H.M., Briggs, J.A., García-Sáez, A.J., Nickel, W. (2012 )
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2)-dependent oligomerization of fibroblast growth factor 2 (FGF2) triggers the formation of a lipidic membrane pore implicated in unconventional secretion.
J Biol Chem 287(33): 27659-69 - Malsam, J., Parisotto, D., Bharat, T.A., Scheutzow, A., Krause, J.M., Briggs, J.A., Söllner, T.H. (2012 )
Complexin arrests a pool of docked vesicles for fast Ca2+-dependent release.
EMBO J 31(15): 3270-81 - Bharat, T.A., Davey, N.E., Ulbrich, P., Riches, J.D., de Marco, A., Rumlova, M., Sachse, C., Ruml, T., Briggs, J.A. (2012 )
Structure of the immature retroviral capsid at 8 Å resolution by cryo-electron microscopy.
Nature 487(7407): 385-9 - Bharat, T.A., Noda, T., Riches, J.D., Kraehling, V., Kolesnikova, L., Becker, S., Kawaoka, Y., Briggs, J.A. (2012 )
Structural dissection of Ebola virus and its assembly determinants using cryo-electron tomography.
Proc Natl Acad Sci U S A 109(11): 4275-80
2011
- Bharat, T.A., Riches, J.D., Kolesnikova, L., Welsch, S., Krähling, V., Davey, N., Parsy, M.L., Becker, S., Briggs, J.A. (2011 )
Cryo-electron tomography of Marburg virus particles and their morphogenesis within infected cells.
PLoS Biol 9(11): e1001196
2008
- Bharat, T.A., Eisenbeis, S., Zeth, K., Höcker, B. (2008 )
A beta alpha-barrel built by the combination of fragments from different folds.
Proc Natl Acad Sci U S A 105(29): 9942-7