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Recent publications

https://www.researchgate.net/profile/Philipp_Holliger

  1. Arangundy-Franklin S, Taylor AI, Porebski BT, Genna V, Peak-Chew S, Vaisman A, Woodgate R, Orozco M, Holliger P (2019)
    A synthetic genetic polymer with an uncharged backbone chemistry based on alkyl phosphonate nucleic acids.
    Nature Chemistry in press  2019. doi: 10.1038/s41557-019-0255-4.
  2. Mutschler H, Taylor AI, Porebski BT, Lightowlers A, Houlihan G, Abramov M, Herdewijn P & Holliger P (2018)
    Random-sequence genetic oligomer pools display an innate potential for ligation and recombination.
    eLife.  7: e43022. doi: 10.7554 / eLife.43022.
  3. Attwater J, Raguram A, Morgunov AS, Gianni E & Holliger P (2018)
    Ribozyme-catalysed RNA synthesis using triplet building blocks.
    eLife. 7: e35255. doi: 10.7554 / eLife.35255.
  4. Tagami S, Attwater J & Holliger P (2017)
    Simple peptides derived from the ribosomal core potentiate RNA polymerase ribozyme function.
    Nature Chemistry. 9 : 325-332.
  5. Mutschler H, Wochner A & Holliger P. (2015)
    Freeze-thaw cycles as drivers of complex ribozyme assembly.
    Nature Chemistry; 7 :502-08.
  6. Taylor AI, Pinheiro VB, Smola MJ, Morgunov AS, Peak-Chew SY, Cozens C, Weeks KM, Herdewijn P & Holliger P. (2015)
    Catalysts from synthetic genetic polymers.
    Nature, 518 : 427-30.
  7. Cozens C, Mutschler H, Helson G, Houlihan G, Taylor AI & Holliger P (2015
    Enzymatic Synthesis Of Nucleic Acids With Defined Regioisomeric 2’-5’ Linkages.
    Angew. Chem. Intl. Ed. 54 : 15570-73.
  8. Attwater J, Wochner A & Holliger P. (2013)
    In-ice evolution of RNA polymerase ribozyme activity.
    Nature Chem.; 5 : 1011-8.
  9. Synthetic genetic polymers capable of heredity and evolution.
    Pinheiro VB, Taylor AI, Cozens C, Abramov M, Renders M, Zhang S, Chaput JC, Wengel J, Peak-Chew SY, McLaughlin SH, Herdewijn P, Holliger P.
    Science. 2012; 336 : 341-4.
    (F1000: 11*, featured in Nature, Nature Methods, Nature Biotechnology, Scientific American, New Scientist, NASA Astrobiology, RSc Chemistry World etc.)
  10. Ribozyme-catalyzed transcription of an active ribozyme.
    Wochner A, Attwater J, Coulson A, Holliger P.
    Science. 2011; 332 :209-12.
    (F1000: 14*, featured in Nature, Nature Methods, New Scientist, RSc Chemistry World, ChemEng News)