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2024
- Brito Querido, J., et al. (8th August 2024)
Human tumor suppressor protein Pdcd4 binds at the mRNA entry channel in the 40S small ribosomal subunit.
Nat Commun 15(1): 6633 - Brito Querido, J., Sokabe, M., Díaz-López, I., Gordiyenko, Y., Fraser, C.S., Ramakrishnan, V. (29th March 2024)
The structure of a human translation initiation complex reveals two independent roles for the helicase eIF4A.
Nat Struct Mol Biol 31(3): 455-464 - Brito Querido, J., Díaz-López, I., Ramakrishnan, V. (5th March 2024)
The molecular basis of translation initiation and its regulation in eukaryotes.
Nat Rev Mol Cell Biol 25(3): 168-186
2021
- Chandrasekaran, V., Desai, N., Burton, N.O., Yang, H., Price, J., Miska, E.A., Ramakrishnan, V. (5th October 2021)
Visualizing formation of the active site in the mitochondrial ribosome.
Elife 10
2020
- Desai, N., Yang, H., Chandrasekaran, V., Kazi, R., Minczuk, M., Ramakrishnan, V. (27th November 2020)
Elongational stalling activates mitoribosome-associated quality control.
Science 370(6520): 1105-1110 - Brito Querido, J., et al. (4th September 2020)
Structure of a human 48 translational initiation complex.
Science 369(6508): 1220-1227
2019
- Chandrasekaran, V., et al. (25th December 2019)
Mechanism of ribosome stalling during translation of a poly(A) tail.
Nat Struct Mol Biol 26(12): 1132-1140 - Gordiyenko, Y., Llácer, J.L., Ramakrishnan, V. (14th June 2019)
Structural basis for the inhibition of translation through eIF2α phosphorylation.
Nat Commun 10(1): 2640 - Rae, C.D., Gordiyenko, Y., Ramakrishnan, V. (15th February 2019)
How a circularized tmRNA moves through the ribosome.
Science 363(6428): 740-744
2018
- Llácer, J.L., et al. (30th November 2018)
Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Elife 7 - Ramakrishnan, V., Henderson, R. (23rd November 2018)
Thomas A. Steitz (1940-2018).
Science 362(6417): 897 - Juszkiewicz, S., Chandrasekaran, V., Lin, Z., Kraatz, S., Ramakrishnan, V., Hegde, R.S. (1st November 2018)
ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol Cell 72(3): 469-481.e7
2017
- Brown, A., et al. (11th October 2017)
Structures of the human mitochondrial ribosome in native states of assembly.
Nat Struct Mol Biol 24(10): 866-869 - Desai, N., Brown, A., Amunts, A., Ramakrishnan, V. (3rd February 2017)
The structure of the yeast mitochondrial ribosome.
Science 355(6324): 528-531 - Ramakrishnan, V.R., Gitomer, S., Kofonow, J.M., Robertson, C.E., Frank, D.N. (14th January 2017)
Investigation of sinonasal microbiome spatial organization in chronic rhinosinusitis.
Int Forum Allergy Rhinol 7(1): 16-23
2016
- James, N.R., Brown, A., Gordiyenko, Y., Ramakrishnan, V. (16th December 2016)
Translational termination without a stop codon.
Science 354(6318): 1437-1440 - Shao, S., Murray, J., Brown, A., Taunton, J., Ramakrishnan, V., Hegde, R.S. (17th November 2016)
Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
Cell 167(5): 1229-1240.e15 - Hussain, T., Llácer, J.L., Wimberly, B.T., Kieft, J.S., Ramakrishnan, V. (22nd September 2016)
Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
Cell 167(1): 133-144.e13 - Hauser, L.J., Ir, D., Kingdom, T.T., Robertson, C.E., Frank, D.N., Ramakrishnan, V.R. (17th August 2016)
Evaluation of bacterial transmission to the paranasal sinuses through sinus irrigation.
Int Forum Allergy Rhinol 6(8): 800-6 - Brown, A., Fernández, I.S., Gordiyenko, Y., Ramakrishnan, V. (9th June 2016)
Ribosome-dependent activation of stringent control.
Nature 534(7606): 277-280 - Murray, J., Savva, C.G., Shin, B.S., Dever, T.E., Ramakrishnan, V., Fernández, I.S. (9th May 2016)
Structural characterization of ribosome recruitment and translocation by type IV IRES.
Elife 5 - Hauser, L.J., Ir, D., Kingdom, T.T., Robertson, C.E., Frank, D.N., Ramakrishnan, V.R. (21st January 2016)
Investigation of bacterial repopulation after sinus surgery and perioperative antibiotics.
Int Forum Allergy Rhinol 6(1): 34-40 - Lee, J.T., Frank, D.N., Ramakrishnan, V. (2016)
Microbiome of the paranasal sinuses: Update and literature review.
Am J Rhinol Allergy 30(1): 3-16
2015
- Ramakrishnan, V.R., Frank, D.N. (14th November 2015)
Impact of cigarette smoking on the middle meatus microbiome in health and chronic rhinosinusitis.
Int Forum Allergy Rhinol 5(11): 981-9 - Brown, A., Shao, S., Murray, J., Hegde, R.S., Ramakrishnan, V. (27th August 2015)
Structural basis for stop codon recognition in eukaryotes.
Nature 524(7566): 493-496 - Ramakrishnan, V.R., Hauser, L.J., Feazel, L.M., Ir, D., Robertson, C.E., Frank, D.N. (26th August 2015)
Sinus microbiota varies among chronic rhinosinusitis phenotypes and predicts surgical outcome.
J Allergy Clin Immunol 136(2): 334-42.e1 - Llácer, J.L., et al. (6th August 2015)
Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Mol Cell 59(3): 399-412 - Keane, S.C., et al. (22nd May 2015)
RNA structure. Structure of the HIV-1 RNA packaging signal.
Science 348(6237): 917-21 - Amunts, A., Brown, A., Toots, J., Scheres, S.H.W., Ramakrishnan, V. (3rd April 2015)
Ribosome. The structure of the human mitochondrial ribosome.
Science 348(6230): 95-98 - Amunts, A., Fiedorczuk, K., Truong, T.T., Chandler, J., Greenberg, E.P., Ramakrishnan, V. (27th February 2015)
Bactobolin A binds to a site on the 70S ribosome distinct from previously seen antibiotics.
J Mol Biol 427(4): 753-755 - Hauser, L.J., et al. (2nd January 2015)
Sinus culture poorly predicts resident microbiota.
Int Forum Allergy Rhinol 5(1): 3-9
2014
- Ramakrishnan, V. (20th November 2014)
The ribosome emerges from a black box.
Cell 159(5): 979-984 - Brown, A., et al. (7th November 2014)
Structure of the large ribosomal subunit from human mitochondria.
Science 346(6210): 718-722 - Hussain, T., et al. (23rd October 2014)
Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
Cell 159(3): 597-607 - Fernández, I.S., Bai, X.C., Murshudov, G., Scheres, S.H., Ramakrishnan, V. (8th May 2014)
Initiation of translation by cricket paralysis virus IRES requires its translocation in the ribosome.
Cell 157(4): 823-31 - Amunts, A., et al. (28th March 2014)
Structure of the yeast mitochondrial large ribosomal subunit.
Science 343(6178): 1485-1489 - Ban, N., et al. (10th February 2014)
A new system for naming ribosomal proteins.
Curr Opin Struct Biol 24: 165-9 - Metri, R., Jerath, G., Kailas, G., Gacche, N., Pal, A., Ramakrishnan, V. (2014)
Structure-based barcoding of proteins.
Protein Sci 23(1): 117-20 - Perez-Fernandez, D., et al. (2014)
4'-O-substitutions determine selectivity of aminoglycoside antibiotics.
Nat Commun 5: 3112
2013
- Ramakrishnan, V.R., Feazel, L.M., Gitomer, S.A., Ir, D., Robertson, C.E., Frank, D.N. (30th December 2013)
The microbiome of the middle meatus in healthy adults.
PLoS One 8(12): e85507 - Fernández, I.S., et al. (15th November 2013)
Molecular architecture of a eukaryotic translational initiation complex.
Science 342(6160): 1240585 - Tourigny, D.S., et al. (23rd October 2013)
Crystal structure of a bioactive pactamycin analog bound to the 30S ribosomal subunit.
J Mol Biol 425(20): 3907-10 - Akers, J.C., et al. (21st October 2013)
MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development.
PLoS One 8(10): e78115 - Agirrezabala, X., Fernández, I.S., Kelley, A.C., Cartón, D.G., Ramakrishnan, V., Valle, M. (23rd September 2013)
The ribosome triggers the stringent response by RelA via a highly distorted tRNA.
EMBO Rep 14(9): 811-6 - Fernández, I.S., Ng, C.L., Kelley, A.C., Wu, G., Yu, Y.T., Ramakrishnan, V. (1st August 2013)
Unusual base pairing during the decoding of a stop codon by the ribosome.
Nature 500(7460): 107-10 - Tourigny, D.S., Fernández, I.S., Kelley, A.C., Ramakrishnan, V. (28th June 2013)
Elongation factor G bound to the ribosome in an intermediate state of translocation.
Science 340(6140): 1235490 - Voorhees, R.M., Mandal, D., Neubauer, C., Köhrer, C., RajBhandary, U.L., Ramakrishnan, V. (31st May 2013)
The structural basis for specific decoding of AUA by isoleucine tRNA on the ribosome.
Nat Struct Mol Biol 20(5): 641-3 - Voorhees, R.M., Ramakrishnan, V. (2013)
Structural basis of the translational elongation cycle.
Annu Rev Biochem 82: 203-36
2012
- Matt, T., et al. (3rd July 2012)
Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin.
Proc Natl Acad Sci U S A 109(27): 10984-9 - Selmer, M., Gao, Y.G., Weixlbaumer, A., Ramakrishnan, V. (17th May 2012)
Ribosome engineering to promote new crystal forms.
Acta Crystallogr D Biol Crystallogr 68(Pt 5): 578-83 - Neubauer, C., Gillet, R., Kelley, A.C., Ramakrishnan, V. (16th March 2012)
Decoding in the absence of a codon by tmRNA and SmpB in the ribosome.
Science 335(6074): 1366-9
2011
- Jin, H., Kelley, A.C., Ramakrishnan, V. (20th September 2011)
Crystal structure of the hybrid state of ribosome in complex with the guanosine triphosphatase release factor 3.
Proc Natl Acad Sci U S A 108(38): 15798-803 - Ramakrishnan, V. (20th September 2011)
Profile of Venkatraman Ramakrishnan. Interview by Prashant Nair.
Proc Natl Acad Sci U S A 108(38): 15676-8 - Schmeing, T.M., Voorhees, R.M., Kelley, A.C., Ramakrishnan, V. (6th April 2011)
How mutations in tRNA distant from the anticodon affect the fidelity of decoding.
Nat Struct Mol Biol 18(4): 432-6 - Ramakrishnan, V. (11th February 2011)
Molecular biology. The eukaryotic ribosome.
Science 331(6018): 681-2
2010
- Demirci, H., et al. (20th December 2010)
Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function.
RNA 16(12): 2319-24 - Voorhees, R.M., Schmeing, T.M., Kelley, A.C., Ramakrishnan, V. (5th November 2010)
The mechanism for activation of GTP hydrolysis on the ribosome.
Science 330(6005): 835-838 - Ng, C.L., Lang, K., Meenan, N.A., Sharma, A., Kelley, A.C., Kleanthous, C., Ramakrishnan, V. (19th October 2010)
Structural basis for 16S ribosomal RNA cleavage by the cytotoxic domain of colicin E3.
Nat Struct Mol Biol 17(10): 1241-1246 - Ramakrishnan, V. (14th June 2010)
Unraveling the structure of the ribosome (Nobel Lecture).
Angew Chem Int Ed Engl 49(26): 4355-80 - Jin, H., Kelley, A.C., Loakes, D., Ramakrishnan, V. (11th May 2010)
Structure of the 70S ribosome bound to release factor 2 and a substrate analog provides insights into catalysis of peptide release.
Proc Natl Acad Sci U S A 107(19): 8593-8
2009
- Kumar, A., Ramakrishnan, V., Ranbhor, R., Patel, K., Durani, S. (24th December 2009)
Homochiral stereochemistry: the missing link of structure to energetics in protein folding.
J Phys Chem B 113(51): 16435-42 - Neubauer, C., et al. (11th December 2009)
The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.
Cell 139(6): 1084-95 - Ramakrishnan, V. (2nd December 2009)
The ribosome: some hard facts about its structure and hot air about its evolution.
Cold Spring Harb Symp Quant Biol 74: 25-33 - Schmeing, T.M., Voorhees, R.M., Kelley, A.C., Gao, Y.G., Murphy, F.V., Weir, J.R., Ramakrishnan, V. (30th October 2009)
The crystal structure of the ribosome bound to EF-Tu and aminoacyl-tRNA.
Science 326(5953): 688-694 - Gao, Y.G., Selmer, M., Dunham, C.M., Weixlbaumer, A., Kelley, A.C., Ramakrishnan, V. (30th October 2009)
The structure of the ribosome with elongation factor G trapped in the posttranslocational state.
Science 326(5953): 694-9 - Schmeing, T.M., Ramakrishnan, V. (29th October 2009)
What recent ribosome structures have revealed about the mechanism of translation.
Nature 461(7268): 1234-42 - Aaltonen, T., et al. (19th June 2009)
Evidence for a narrow near-threshold structure in the J/psivarphi mass spectrum in B;{+} --> J/psivarphiK;{+} decays.
Phys Rev Lett 102(24): 242002 - Voorhees, R.M., Weixlbaumer, A., Loakes, D., Kelley, A.C., Ramakrishnan, V. (12th May 2009)
Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome.
Nat Struct Mol Biol 16(5): 528-33 - Schuette, J.C., et al. (18th March 2009)
GTPase activation of elongation factor EF-Tu by the ribosome during decoding.
EMBO J 28(6): 755-65
2008
- Weixlbaumer, A., Jin, H., Neubauer, C., Voorhees, R.M., Petry, S., Kelley, A.C., Ramakrishnan, V. (7th November 2008)
Insights into translational termination from the structure of RF2 bound to the ribosome.
Science 322(5903): 953-6 - Ramakrishnan, V. (2008)
What we have learned from ribosome structures.
Biochem Soc Trans 36(Pt 4): 567-74 - Kurata, S., et al. (4th July 2008)
Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U.G wobble pairing during decoding.
J Biol Chem 283(27): 18801-11 - Petry, S., Weixlbaumer, A., Ramakrishnan, V. (2008)
The termination of translation.
Curr Opin Struct Biol 18(1): 70-7
2007
- Weixlbaumer, A., Petry, S., Dunham, C.M., Selmer, M., Kelley, A.C., Ramakrishnan, V. (29th August 2007)
Crystal structure of the ribosome recycling factor bound to the ribosome.
Nat Struct Mol Biol 14(8): 733-7 - Weixlbaumer, A., et al. (13th June 2007)
Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines.
Nat Struct Mol Biol 14(6): 498-502 - Dunham, C.M., Selmer, M., Phelps, S.S., Kelley, A.C., Suzuki, T., Joseph, S., Ramakrishnan, V. (6th June 2007)
Structures of tRNAs with an expanded anticodon loop in the decoding center of the 30S ribosomal subunit.
RNA 13(6): 817-23 - Passmore, L.A., et al. (13th April 2007)
The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome.
Mol Cell 26(1): 41-50
2006
- Selmer, M., et al. (29th September 2006)
Structure of the 70S ribosome complexed with mRNA and tRNA.
Science 313(5795): 1935-42
2005
- Petry, S., et al. (29th December 2005)
Crystal structures of the ribosome in complex with release factors RF1 and RF2 bound to a cognate stop codon.
Cell 123(7): 1255-66 - Daviter, T., Murphy, F.V., Ramakrishnan, V. (20th May 2005)
Molecular biology. A renewed focus on transfer RNA.
Science 308(5725): 1123-4 - Ramakrishnan, V., Ogram, A.V., Lindner, A.S. (2005)
Impacts of co-solvent flushing on microbial populations capable of degrading trichloroethylene.
Environ Health Perspect 113(1): 55-61 - Ogle, J.M., Ramakrishnan, V. (2005)
Structural insights into translational fidelity.
Annu Rev Biochem 74: 129-77
2004
- Murphy, F.V., Ramakrishnan, V., Malkiewicz, A., Agris, P.F. (21st December 2004)
The role of modifications in codon discrimination by tRNA(Lys)UUU.
Nat Struct Mol Biol 11(12): 1186-91 - Murphy, F.V., Ramakrishnan, V. (21st December 2004)
Structure of a purine-purine wobble base pair in the decoding center of the ribosome.
Nat Struct Mol Biol 11(12): 1251-2 - Razeto, A., et al. (13th February 2004)
Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain.
J Mol Biol 336(2): 319-29
2003
- Brodersen, D.E., Clemons, W.M., Carter, A.P., Wimberly, B.T., Ramakrishnan, V. (23rd November 2003)
Phasing the 30S ribosomal subunit structure.
Acta Crystallogr D Biol Crystallogr 59(Pt 11): 2044-50 - Ogle, J.M., Carter, A.P., Ramakrishnan, V. (2003)
Insights into the decoding mechanism from recent ribosome structures.
Trends Biochem Sci 28(5): 259-66 - Valle, M., Gillet, R., Kaur, S., Henne, A., Ramakrishnan, V., Frank, J. (4th April 2003)
Visualizing tmRNA entry into a stalled ribosome.
Science 300(5616): 127-30 - Brodersen, D.E., Ramakrishnan, V. (2003)
Shape can be seductive.
Nat Struct Biol 10(2): 78-80
2002
- Ogle, J.M., Murphy, F.V., Tarry, M.J., Ramakrishnan, V. (27th November 2002)
Selection of tRNA by the ribosome requires a transition from an open to a closed form.
Cell 111(5): 721-32 - Ramakrishnan, V. (22nd February 2002)
Ribosome structure and the mechanism of translation.
Cell 108(4): 557-72 - Brodersen, D.E., Clemons, W.M., Carter, A.P., Wimberly, B.T., Ramakrishnan, V. (22nd February 2002)
Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 S RNA.
J Mol Biol 316(3): 725-68 - Arndt, J.W., Hao, B., Ramakrishnan, V., Cheng, T., Chan, S.I., Chan, M.K. (2002)
Crystal structure of a novel carboxypeptidase from the hyperthermophilic archaeon Pyrococcus furiosus.
Structure 10(2): 215-24
2001
- Clemons, W.M., et al. (20th July 2001)
Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: purification, crystallization and structure determination.
J Mol Biol 310(4): 827-43 - Ogle, J.M., Brodersen, D.E., Clemons, W.M., Tarry, M.J., Carter, A.P., Ramakrishnan, V. (4th May 2001)
Recognition of cognate transfer RNA by the 30S ribosomal subunit.
Science 292(5518): 897-902 - Ramakrishnan, V., Moore, P.B. (2001)
Atomic structures at last: the ribosome in 2000.
Curr Opin Struct Biol 11(2): 144-54 - Carter, A.P., et al. (19th January 2001)
Crystal structure of an initiation factor bound to the 30S ribosomal subunit.
Science 291(5503): 498-501 - Brodersen, D.E., et al. (2001)
Atomic structures of the 30S subunit and its complexes with ligands and antibiotics.
Cold Spring Harb Symp Quant Biol 66: 17-32
2000
- Brodersen, D.E., Clemons, W.M., Carter, A.P., Morgan-Warren, R.J., Wimberly, B.T., Ramakrishnan, V. (22nd December 2000)
The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit.
Cell 103(7): 1143-54 - Wimberly, B.T., et al. (21st September 2000)
Structure of the 30S ribosomal subunit.
Nature 407(6802): 327-39 - Carter, A.P., Clemons, W.M., Brodersen, D.E., Morgan-Warren, R.J., Wimberly, B.T., Ramakrishnan, V. (21st September 2000)
Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics.
Nature 407(6802): 340-8 - Allard, P., et al. (15th August 2000)
Another piece of the ribosome: solution structure of S16 and its location in the 30S subunit.
Structure 8(8): 875-82 - Shu, F., Ramakrishnan, V., Schoenborn, B.P. (11th April 2000)
Enhanced visibility of hydrogen atoms by neutron crystallography on fully deuterated myoglobin.
Proc Natl Acad Sci U S A 97(8): 3872-7
1999
- Angus-Hill, M.L., Dutnall, R.N., Tafrov, S.T., Sternglanz, R., Ramakrishnan, V. (17th December 1999)
Crystal structure of the histone acetyltransferase Hpa2: A tetrameric member of the Gcn5-related N-acetyltransferase superfamily.
J Mol Biol 294(5): 1311-25 - Clemons, W.M., Gowda, K., Black, S.D., Zwieb, C., Ramakrishnan, V. (24th September 1999)
Crystal structure of the conserved subdomain of human protein SRP54M at 2.1 A resolution: evidence for the mechanism of signal peptide binding.
J Mol Biol 292(3): 697-705 - Clemons, W.M., May, J.L., Wimberly, B.T., McCutcheon, J.P., Capel, M.S., Ramakrishnan, V. (26th August 1999)
Structure of a bacterial 30S ribosomal subunit at 5.5 A resolution.
Nature 400(6747): 833-40 - Wimberly, B.T., Guymon, R., McCutcheon, J.P., White, S.W., Ramakrishnan, V. (14th May 1999)
A detailed view of a ribosomal active site: the structure of the L11-RNA complex.
Cell 97(4): 491-502 - McCutcheon, J.P., et al. (13th April 1999)
Location of translational initiation factor IF3 on the small ribosomal subunit.
Proc Natl Acad Sci U S A 96(8): 4301-6
1998
- Zhou, Y.B., Gerchman, S.E., Ramakrishnan, V., Travers, A., Muyldermans, S. (24th September 1998)
Position and orientation of the globular domain of linker histone H5 on the nucleosome.
Nature 395(6700): 402-5 - Dutnall, R.N., Tafrov, S.T., Sternglanz, R., Ramakrishnan, V. (21st August 1998)
Structure of the histone acetyltransferase Hat1: a paradigm for the GCN5-related N-acetyltransferase superfamily.
Cell 94(4): 427-38 - Davies, C., Gerstner, R.B., Draper, D.E., Ramakrishnan, V., White, S.W. (17th August 1998)
The crystal structure of ribosomal protein S4 reveals a two-domain molecule with an extensive RNA-binding surface: one domain shows structural homology to the ETS DNA-binding motif.
EMBO J 17(16): 4545-58 - Davies, C., Bussiere, D.E., Golden, B.L., Porter, S.J., Ramakrishnan, V., White, S.W. (19th June 1998)
Ribosomal proteins S5 and L6: high-resolution crystal structures and roles in protein synthesis and antibiotic resistance.
J Mol Biol 279(4): 873-88 - Ramakrishnan, V., White, S.W. (1998)
Ribosomal protein structures: insights into the architecture, machinery and evolution of the ribosome.
Trends Biochem Sci 23(6): 208-12 - Clemons, W.M., Davies, C., White, S.W., Ramakrishnan, V. (15th April 1998)
Conformational variability of the N-terminal helix in the structure of ribosomal protein S15.
Structure 6(4): 429-38 - Dutnall, R.N., Tafrov, S.T., Sternglanz, R., Ramakrishnan, V. (1998)
Structure of the yeast histone acetyltransferase Hat1: insights into substrate specificity and implications for the Gcn5-related N-acetyltransferase superfamily.
Cold Spring Harb Symp Quant Biol 63: 501-7
1997
- Dutnall, R.N., Ramakrishnan, V. (15th October 1997)
Twists and turns of the nucleosome: tails without ends.
Structure 5(10): 1255-9 - Wimberly, B.T., White, S.W., Ramakrishnan, V. (15th September 1997)
The structure of ribosomal protein S7 at 1.9 A resolution reveals a beta-hairpin motif that binds double-stranded nucleic acids.
Structure 5(9): 1187-98 - Ramakrishnan, V., Biou, V. (1997)
[31] Treatment of multiwavelength anomalous diffraction data as a special case of multiple isomorphous replacement.
Methods Enzymol 276: 538-557 - Ramakrishnan, V. (1997)
Histone structure and the organization of the nucleosome.
Annu Rev Biophys Biomol Struct 26: 83-112 - Ramakrishnan, V. (1997)
Histone H1 and chromatin higher-order structure.
Crit Rev Eukaryot Gene Expr 7(3): 215-30 - Ramakrishnan, V., Biou, V. (1997)
Treatment of multiwavelength anomalous diffraction data as a special case of multiple isomorphous replacement.
Methods Enzymol 276: 538-57
1996
- Hoffman, D.W., Cameron, C.S., Davies, C., White, S.W., Ramakrishnan, V. (20th December 1996)
Ribosomal protein L9: a structure determination by the combined use of X-ray crystallography and NMR spectroscopy.
J Mol Biol 264(5): 1058-71 - Davies, C., Ramakrishnan, V., White, S.W. (15th September 1996)
Structural evidence for specific S8-RNA and S8-protein interactions within the 30S ribosomal subunit: ribosomal protein S8 from Bacillus stearothermophilus at 1.9 A resolution.
Structure 4(9): 1093-104 - Goytisolo, F.A., Gerchman, S.E., Yu, X., Rees, C., Graziano, V., Ramakrishnan, V., Thomas, J.O. (1st July 1996)
Identification of two DNA-binding sites on the globular domain of histone H5.
EMBO J 15(13): 3421-9 - Hamiche, A., Schultz, P., Ramakrishnan, V., Oudet, P., Prunell, A. (22nd March 1996)
Linker histone-dependent DNA structure in linear mononucleosomes.
J Mol Biol 257(1): 30-42 - Jaishree, T.N., Ramakrishnan, V., White, S.W. (5th March 1996)
Solution structure of prokaryotic ribosomal protein S17 by high-resolution NMR spectroscopy.
Biochemistry 35(9): 2845-53 - Davies, C., White, S.W., Ramakrishnan, V. (15th January 1996)
The crystal structure of ribosomal protein L14 reveals an important organizational component of the translational apparatus.
Structure 4(1): 55-66 - Shu, F., Ramakrishnan, V., Schoenborn, B.P. (1996)
High-level expression and deuteration of sperm whale myoglobin. A study of its solvent structure by X-ray and neutron diffraction methods.
Basic Life Sci 64: 309-23 - Graziano, V., Gerchman, S.E., Schneider, D.K., Ramakrishnan, V. (1996)
Neutron scattering studies on chromatin higher-order structure.
Basic Life Sci 64: 127-36
1995
- Ramakrishnan, V. (5th December 1995)
The histone fold: evolutionary questions.
Proc Natl Acad Sci U S A 92(25): 11328-30 - Biou, V., Shu, F., Ramakrishnan, V. (15th August 1995)
X-ray crystallography shows that translational initiation factor IF3 consists of two compact alpha/beta domains linked by an alpha-helix.
EMBO J 14(16): 4056-64 - Kycia, J.H., Biou, V., Shu, F., Gerchman, S.E., Graziano, V., Ramakrishnan, V. (9th May 1995)
Prokaryotic translation initiation factor IF3 is an elongated protein consisting of two crystallizable domains.
Biochemistry 34(18): 6183-7 - Ramakrishnan, V., et al. (1995)
Structures of prokaryotic ribosomal proteins: implications for RNA binding and evolution.
Biochem Cell Biol 73(11-12): 979-86
1994
- Cerf, C., et al. (20th September 1994)
Homo- and heteronuclear two-dimensional NMR studies of the globular domain of histone H1: full assignment, tertiary structure, and comparison with the globular domain of histone H5.
Biochemistry 33(37): 11079-86 - Davies, C., Gerchman, S.E., Kycia, J.H., McGee, K., Ramakrishnan, V., White, S.W. (1st September 1994)
Crystallization and preliminary X-ray diffraction studies of bacterial ribosomal protein L14.
Acta Crystallogr D Biol Crystallogr 50(Pt 5): 790-2 - Gerchman, S.E., Graziano, V., Ramakrishnan, V. (1994)
Expression of chicken linker histones in E. coli: sources of problems and methods for overcoming some of the difficulties.
Protein Expr Purif 5(3): 242-51 - Graziano, V., Gerchman, S.E., Schneider, D.K., Ramakrishnan, V. (24th March 1994)
Histone H1 is located in the interior of the chromatin 30-nm filament.
Nature 368(6469): 351-4 - Hoffman, D.W., Davies, C., Gerchman, S.E., Kycia, J.H., Porter, S.J., White, S.W., Ramakrishnan, V. (1st January 1994)
Crystal structure of prokaryotic ribosomal protein L9: a bi-lobed RNA-binding protein.
EMBO J 13(1): 205-12
1993
- Golden, B.L., Ramakrishnan, V., White, S.W. (15th December 1993)
Ribosomal protein L6: structural evidence of gene duplication from a primitive RNA binding protein.
EMBO J 12(13): 4901-8 - Golden, B.L., Hoffman, D.W., Ramakrishnan, V., White, S.W. (30th November 1993)
Ribosomal protein S17: characterization of the three-dimensional structure by 1H and 15N NMR.
Biochemistry 32(47): 12812-20 - Cerf, C., et al. (26th October 1993)
Homo- and heteronuclear two-dimensional NMR studies of the globular domain of histone H1: sequential assignment and secondary structure.
Biochemistry 32(42): 11345-51 - Ramakrishnan, V., Finch, J.T., Graziano, V., Lee, P.L., Sweet, R.M. (18th March 1993)
Crystal structure of globular domain of histone H5 and its implications for nucleosome binding.
Nature 362(6417): 219-23
1992
- Ramakrishnan, V., White, S.W. (27th August 1992)
The structure of ribosomal protein S5 reveals sites of interaction with 16S rRNA.
Nature 358(6389): 768-71
1991
- Mangel, W.F., Lin, B.H., Ramakrishnan, V. (25th May 1991)
Conformation of one- and two-chain high molecular weight urokinase analyzed by small-angle neutron scattering and vacuum ultraviolet circular dichroism.
J Biol Chem 266(15): 9408-12 - Ramakrishnan, V., Patthy, L., Mangel, W.F. (23rd April 1991)
Conformation of Lys-plasminogen and the kringle 1-3 fragment of plasminogen analyzed by small-angle neutron scattering.
Biochemistry 30(16): 3963-9 - Ramakrishnan, V., Gerchman, S.E. (15th January 1991)
Cloning, sequencing, and overexpression of genes for ribosomal proteins from Bacillus stearothermophilus.
J Biol Chem 266(2): 880-5
1990
- Graziano, V., Ramakrishnan, V. (20th August 1990)
Interaction of HMG14 with chromatin.
J Mol Biol 214(4): 897-910 - Mangel, W.F., Lin, B.H., Ramakrishnan, V. (6th April 1990)
Characterization of an extremely large, ligand-induced conformational change in plasminogen.
Science 248(4951): 69-73 - Graziano, V., et al. (20th March 1990)
Crystallization of the globular domain of histone H5.
J Mol Biol 212(2): 253-7 - Ramakrishnan, V., Sinicropi, D.V., Dere, R., Darbonne, W.C., Bechtol, K.B., Baker, J.B. (15th February 1990)
Interaction of wild-type and catalytically inactive mutant forms of tissue-type plasminogen activator with human umbilical vein endothelial cell monolayers.
J Biol Chem 265(5): 2755-62
1988
- Graziano, V., Gerchman, S.E., Ramakrishnan, V. (20th October 1988)
Reconstitution of chromatin higher-order structure from histone H5 and depleted chromatin.
J Mol Biol 203(4): 997-1007 - Capel, M.S., Ramakrishnan, V. (1988)
Neutron-scattering topography of proteins of the small ribosomal subunit.
Methods Enzymol 164: 117-31
1987
- Capel, M.S., et al. (4th December 1987)
A complete mapping of the proteins in the small ribosomal subunit of Escherichia coli.
Science 238(4832): 1403-6 - Gerchman, S.E., Ramakrishnan, V. (1987)
Chromatin higher-order structure studied by neutron scattering and scanning transmission electron microscopy.
Proc Natl Acad Sci U S A 84(22): 7802-6
1986
- Ramakrishnan, V., Graziano, V., Capel, M.S. (15th November 1986)
A role for proteins S3 and S14 in the 30 S ribosomal subunit.
J Biol Chem 261(32): 15049-52 - Ramakrishnan, V. (28th March 1986)
Distribution of protein and RNA in the 30S ribosomal subunit.
Science 231(4745): 1562-4
1984
- Wobbe, C.R., Mitra, S., Ramakrishnan, V. (18th December 1984)
Structure of the capsid of Kilham rat virus from small-angle neutron scattering.
Biochemistry 23(26): 6565-9 - Ramakrishnan, V., Capel, M., Kjeldgaard, M., Engelman, D.M., Moore, P.B. (5th April 1984)
Positions of proteins S14, S18 and S20 in the 30 S ribosomal subunit of Escherichia coli.
J Mol Biol 174(2): 265-84 - Donnelly, M.I., Hartman, F.C., Ramakrishnan, V. (10th January 1984)
The shape of ribulose bisphosphate carboxylase/oxygenase in solution as inferred from small angle neutron scattering.
J Biol Chem 259(1): 406-11 - Moore, P.B., et al. (1984)
Neutron scattering and the 30 S ribosomal subunit of E. coli.
Basic Life Sci 27: 73-91
1983
- Uberbacher, E.C., Ramakrishnan, V., Olins, D.E., Bunick, G.J. (11th October 1983)
Neutron scattering studies of nucleosome structure at low ionic strength.
Biochemistry 22(21): 4916-23 - Ramakrishnan, V.R., Darszon, A., Montal, M. (25th April 1983)
A small angle x-ray scattering study of a rhodopsin-lipid complex in hexane.
J Biol Chem 258(8): 4857-60
1981
- Ramakrishnan, V.R., Moore, P.B. (15th December 1981)
Analysis of neutron distance data.
J Mol Biol 153(3): 719-38 - Ramakrishnan, V.R., Yabuki, S., Sillers, I.Y., Schindler, D.G., Engelman, D.M., Moore, P.B. (15th December 1981)
Positions of proteins S6, S11 and S15 in the 30 S ribosomal subunit of Escherichia coli.
J Mol Biol 153(3): 739-60
1980
- Ramakrishnan, V., Darszon, A., Philipp, M., Montal, M. (1980)
Rhodopsin in model membranes: the kinetics of channel opening and closing in rhodopsin-containing planar lipid bilayers.
Ann N Y Acad Sci 358: 36-42