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2021

  • Chandrasekaran, V., Desai, N., Burton, N.O., Yang, H., Price, J., Miska, E.A., Ramakrishnan, V. (5th October 2021)
    Visualizing formation of the active site in the mitochondrial ribosome.
    Elife 10

2020

  • Desai, N., Yang, H., Chandrasekaran, V., Kazi, R., Minczuk, M., Ramakrishnan, V. (27th November 2020)
    Elongational stalling activates mitoribosome-associated quality control.
    Science 370(6520): 1105-1110
  • Brito Querido, J., et al. (4th September 2020)
    Structure of a human 48 translational initiation complex.
    Science 369(6508): 1220-1227

2019

  • Chandrasekaran, V., et al. (25th December 2019)
    Mechanism of ribosome stalling during translation of a poly(A) tail.
    Nat Struct Mol Biol 26(12): 1132-1140
  • Gordiyenko, Y., Llácer, J.L., Ramakrishnan, V. (14th June 2019)
    Structural basis for the inhibition of translation through eIF2α phosphorylation.
    Nat Commun 10(1): 2640
  • Rae, C.D., Gordiyenko, Y., Ramakrishnan, V. (15th February 2019)
    How a circularized tmRNA moves through the ribosome.
    Science 363(6428): 740-744

2018

  • Llácer, J.L., et al. (30th November 2018)
    Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
    Elife 7
  • Ramakrishnan, V., Henderson, R. (23rd November 2018)
    Thomas A. Steitz (1940-2018).
    Science 362(6417): 897
  • Juszkiewicz, S., Chandrasekaran, V., Lin, Z., Kraatz, S., Ramakrishnan, V., Hegde, R.S. (1st November 2018)
    ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
    Mol Cell 72(3): 469-481.e7

2017

  • Brown, A., et al. (11th October 2017)
    Structures of the human mitochondrial ribosome in native states of assembly.
    Nat Struct Mol Biol 24(10): 866-869
  • Desai, N., Brown, A., Amunts, A., Ramakrishnan, V. (3rd February 2017)
    The structure of the yeast mitochondrial ribosome.
    Science 355(6324): 528-531
  • Ramakrishnan, V.R., Gitomer, S., Kofonow, J.M., Robertson, C.E., Frank, D.N. (14th January 2017)
    Investigation of sinonasal microbiome spatial organization in chronic rhinosinusitis.
    Int Forum Allergy Rhinol 7(1): 16-23

2016

  • James, N.R., Brown, A., Gordiyenko, Y., Ramakrishnan, V. (16th December 2016)
    Translational termination without a stop codon.
    Science 354(6318): 1437-1440
  • Shao, S., Murray, J., Brown, A., Taunton, J., Ramakrishnan, V., Hegde, R.S. (17th November 2016)
    Decoding Mammalian Ribosome-mRNA States by Translational GTPase Complexes.
    Cell 167(5): 1229-1240.e15
  • Hussain, T., Llácer, J.L., Wimberly, B.T., Kieft, J.S., Ramakrishnan, V. (22nd September 2016)
    Large-Scale Movements of IF3 and tRNA during Bacterial Translation Initiation.
    Cell 167(1): 133-144.e13
  • Hauser, L.J., Ir, D., Kingdom, T.T., Robertson, C.E., Frank, D.N., Ramakrishnan, V.R. (17th August 2016)
    Evaluation of bacterial transmission to the paranasal sinuses through sinus irrigation.
    Int Forum Allergy Rhinol 6(8): 800-6
  • Brown, A., Fernández, I.S., Gordiyenko, Y., Ramakrishnan, V. (9th June 2016)
    Ribosome-dependent activation of stringent control.
    Nature 534(7606): 277-280
  • Murray, J., Savva, C.G., Shin, B.S., Dever, T.E., Ramakrishnan, V., Fernández, I.S. (9th May 2016)
    Structural characterization of ribosome recruitment and translocation by type IV IRES.
    Elife 5
  • Hauser, L.J., Ir, D., Kingdom, T.T., Robertson, C.E., Frank, D.N., Ramakrishnan, V.R. (21st January 2016)
    Investigation of bacterial repopulation after sinus surgery and perioperative antibiotics.
    Int Forum Allergy Rhinol 6(1): 34-40
  • Lee, J.T., Frank, D.N., Ramakrishnan, V. (2016)
    Microbiome of the paranasal sinuses: Update and literature review.
    Am J Rhinol Allergy 30(1): 3-16

2015

  • Ramakrishnan, V.R., Frank, D.N. (14th November 2015)
    Impact of cigarette smoking on the middle meatus microbiome in health and chronic rhinosinusitis.
    Int Forum Allergy Rhinol 5(11): 981-9
  • Brown, A., Shao, S., Murray, J., Hegde, R.S., Ramakrishnan, V. (27th August 2015)
    Structural basis for stop codon recognition in eukaryotes.
    Nature 524(7566): 493-496
  • Ramakrishnan, V.R., Hauser, L.J., Feazel, L.M., Ir, D., Robertson, C.E., Frank, D.N. (26th August 2015)
    Sinus microbiota varies among chronic rhinosinusitis phenotypes and predicts surgical outcome.
    J Allergy Clin Immunol 136(2): 334-42.e1
  • Llácer, J.L., et al. (6th August 2015)
    Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
    Mol Cell 59(3): 399-412
  • Keane, S.C., et al. (22nd May 2015)
    RNA structure. Structure of the HIV-1 RNA packaging signal.
    Science 348(6237): 917-21
  • Amunts, A., Brown, A., Toots, J., Scheres, S.H.W., Ramakrishnan, V. (3rd April 2015)
    Ribosome. The structure of the human mitochondrial ribosome.
    Science 348(6230): 95-98
  • Amunts, A., Fiedorczuk, K., Truong, T.T., Chandler, J., Greenberg, E.P., Ramakrishnan, V. (27th February 2015)
    Bactobolin A binds to a site on the 70S ribosome distinct from previously seen antibiotics.
    J Mol Biol 427(4): 753-755
  • Hauser, L.J., et al. (2nd January 2015)
    Sinus culture poorly predicts resident microbiota.
    Int Forum Allergy Rhinol 5(1): 3-9

2014

  • Ramakrishnan, V. (20th November 2014)
    The ribosome emerges from a black box.
    Cell 159(5): 979-984
  • Brown, A., et al. (7th November 2014)
    Structure of the large ribosomal subunit from human mitochondria.
    Science 346(6210): 718-722
  • Hussain, T., et al. (23rd October 2014)
    Structural changes enable start codon recognition by the eukaryotic translation initiation complex.
    Cell 159(3): 597-607
  • Fernández, I.S., Bai, X.C., Murshudov, G., Scheres, S.H., Ramakrishnan, V. (8th May 2014)
    Initiation of translation by cricket paralysis virus IRES requires its translocation in the ribosome.
    Cell 157(4): 823-31
  • Amunts, A., et al. (28th March 2014)
    Structure of the yeast mitochondrial large ribosomal subunit.
    Science 343(6178): 1485-1489
  • Ban, N., et al. (10th February 2014)
    A new system for naming ribosomal proteins.
    Curr Opin Struct Biol 24: 165-9
  • Metri, R., Jerath, G., Kailas, G., Gacche, N., Pal, A., Ramakrishnan, V. (2014)
    Structure-based barcoding of proteins.
    Protein Sci 23(1): 117-20
  • Perez-Fernandez, D., et al. (2014)
    4'-O-substitutions determine selectivity of aminoglycoside antibiotics.
    Nat Commun 5: 3112

2013

  • Ramakrishnan, V.R., Feazel, L.M., Gitomer, S.A., Ir, D., Robertson, C.E., Frank, D.N. (30th December 2013)
    The microbiome of the middle meatus in healthy adults.
    PLoS One 8(12): e85507
  • Fernández, I.S., et al. (15th November 2013)
    Molecular architecture of a eukaryotic translational initiation complex.
    Science 342(6160): 1240585
  • Tourigny, D.S., et al. (23rd October 2013)
    Crystal structure of a bioactive pactamycin analog bound to the 30S ribosomal subunit.
    J Mol Biol 425(20): 3907-10
  • Akers, J.C., et al. (21st October 2013)
    MiR-21 in the extracellular vesicles (EVs) of cerebrospinal fluid (CSF): a platform for glioblastoma biomarker development.
    PLoS One 8(10): e78115
  • Agirrezabala, X., Fernández, I.S., Kelley, A.C., Cartón, D.G., Ramakrishnan, V., Valle, M. (23rd September 2013)
    The ribosome triggers the stringent response by RelA via a highly distorted tRNA.
    EMBO Rep 14(9): 811-6
  • Fernández, I.S., Ng, C.L., Kelley, A.C., Wu, G., Yu, Y.T., Ramakrishnan, V. (1st August 2013)
    Unusual base pairing during the decoding of a stop codon by the ribosome.
    Nature 500(7460): 107-10
  • Tourigny, D.S., Fernández, I.S., Kelley, A.C., Ramakrishnan, V. (28th June 2013)
    Elongation factor G bound to the ribosome in an intermediate state of translocation.
    Science 340(6140): 1235490
  • Voorhees, R.M., Mandal, D., Neubauer, C., Köhrer, C., RajBhandary, U.L., Ramakrishnan, V. (31st May 2013)
    The structural basis for specific decoding of AUA by isoleucine tRNA on the ribosome.
    Nat Struct Mol Biol 20(5): 641-3
  • Voorhees, R.M., Ramakrishnan, V. (2013)
    Structural basis of the translational elongation cycle.
    Annu Rev Biochem 82: 203-36

2012

  • Matt, T., et al. (3rd July 2012)
    Dissociation of antibacterial activity and aminoglycoside ototoxicity in the 4-monosubstituted 2-deoxystreptamine apramycin.
    Proc Natl Acad Sci U S A 109(27): 10984-9
  • Selmer, M., Gao, Y.G., Weixlbaumer, A., Ramakrishnan, V. (17th May 2012)
    Ribosome engineering to promote new crystal forms.
    Acta Crystallogr D Biol Crystallogr 68(Pt 5): 578-83
  • Neubauer, C., Gillet, R., Kelley, A.C., Ramakrishnan, V. (16th March 2012)
    Decoding in the absence of a codon by tmRNA and SmpB in the ribosome.
    Science 335(6074): 1366-9

2011

  • Jin, H., Kelley, A.C., Ramakrishnan, V. (20th September 2011)
    Crystal structure of the hybrid state of ribosome in complex with the guanosine triphosphatase release factor 3.
    Proc Natl Acad Sci U S A 108(38): 15798-803
  • Ramakrishnan, V. (20th September 2011)
    Profile of Venkatraman Ramakrishnan. Interview by Prashant Nair.
    Proc Natl Acad Sci U S A 108(38): 15676-8
  • Schmeing, T.M., Voorhees, R.M., Kelley, A.C., Ramakrishnan, V. (6th April 2011)
    How mutations in tRNA distant from the anticodon affect the fidelity of decoding.
    Nat Struct Mol Biol 18(4): 432-6
  • Ramakrishnan, V. (11th February 2011)
    Molecular biology. The eukaryotic ribosome.
    Science 331(6018): 681-2

2010

  • Demirci, H., et al. (20th December 2010)
    Modification of 16S ribosomal RNA by the KsgA methyltransferase restructures the 30S subunit to optimize ribosome function.
    RNA 16(12): 2319-24
  • Voorhees, R.M., Schmeing, T.M., Kelley, A.C., Ramakrishnan, V. (5th November 2010)
    The mechanism for activation of GTP hydrolysis on the ribosome.
    Science 330(6005): 835-838
  • Ng, C.L., Lang, K., Meenan, N.A., Sharma, A., Kelley, A.C., Kleanthous, C., Ramakrishnan, V. (19th October 2010)
    Structural basis for 16S ribosomal RNA cleavage by the cytotoxic domain of colicin E3.
    Nat Struct Mol Biol 17(10): 1241-1246
  • Ramakrishnan, V. (14th June 2010)
    Unraveling the structure of the ribosome (Nobel Lecture).
    Angew Chem Int Ed Engl 49(26): 4355-80
  • Jin, H., Kelley, A.C., Loakes, D., Ramakrishnan, V. (11th May 2010)
    Structure of the 70S ribosome bound to release factor 2 and a substrate analog provides insights into catalysis of peptide release.
    Proc Natl Acad Sci U S A 107(19): 8593-8

2009

  • Kumar, A., Ramakrishnan, V., Ranbhor, R., Patel, K., Durani, S. (24th December 2009)
    Homochiral stereochemistry: the missing link of structure to energetics in protein folding.
    J Phys Chem B 113(51): 16435-42
  • Neubauer, C., et al. (11th December 2009)
    The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE.
    Cell 139(6): 1084-95
  • Ramakrishnan, V. (2nd December 2009)
    The ribosome: some hard facts about its structure and hot air about its evolution.
    Cold Spring Harb Symp Quant Biol 74: 25-33
  • Gao, Y.G., Selmer, M., Dunham, C.M., Weixlbaumer, A., Kelley, A.C., Ramakrishnan, V. (30th October 2009)
    The structure of the ribosome with elongation factor G trapped in the posttranslocational state.
    Science 326(5953): 694-9
  • Schmeing, T.M., Voorhees, R.M., Kelley, A.C., Gao, Y.G., Murphy, F.V., Weir, J.R., Ramakrishnan, V. (30th October 2009)
    The crystal structure of the ribosome bound to EF-Tu and aminoacyl-tRNA.
    Science 326(5953): 688-694
  • Schmeing, T.M., Ramakrishnan, V. (29th October 2009)
    What recent ribosome structures have revealed about the mechanism of translation.
    Nature 461(7268): 1234-42
  • Aaltonen, T., et al. (19th June 2009)
    Evidence for a narrow near-threshold structure in the J/psivarphi mass spectrum in B;{+} --> J/psivarphiK;{+} decays.
    Phys Rev Lett 102(24): 242002
  • Voorhees, R.M., Weixlbaumer, A., Loakes, D., Kelley, A.C., Ramakrishnan, V. (12th May 2009)
    Insights into substrate stabilization from snapshots of the peptidyl transferase center of the intact 70S ribosome.
    Nat Struct Mol Biol 16(5): 528-33
  • Schuette, J.C., et al. (18th March 2009)
    GTPase activation of elongation factor EF-Tu by the ribosome during decoding.
    EMBO J 28(6): 755-65

2008

  • Weixlbaumer, A., Jin, H., Neubauer, C., Voorhees, R.M., Petry, S., Kelley, A.C., Ramakrishnan, V. (7th November 2008)
    Insights into translational termination from the structure of RF2 bound to the ribosome.
    Science 322(5903): 953-6
  • Ramakrishnan, V. (2008)
    What we have learned from ribosome structures.
    Biochem Soc Trans 36(Pt 4): 567-74
  • Kurata, S., et al. (4th July 2008)
    Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U.G wobble pairing during decoding.
    J Biol Chem 283(27): 18801-11
  • Petry, S., Weixlbaumer, A., Ramakrishnan, V. (2008)
    The termination of translation.
    Curr Opin Struct Biol 18(1): 70-7

2007

  • Weixlbaumer, A., Petry, S., Dunham, C.M., Selmer, M., Kelley, A.C., Ramakrishnan, V. (29th August 2007)
    Crystal structure of the ribosome recycling factor bound to the ribosome.
    Nat Struct Mol Biol 14(8): 733-7
  • Weixlbaumer, A., et al. (13th June 2007)
    Mechanism for expanding the decoding capacity of transfer RNAs by modification of uridines.
    Nat Struct Mol Biol 14(6): 498-502
  • Dunham, C.M., Selmer, M., Phelps, S.S., Kelley, A.C., Suzuki, T., Joseph, S., Ramakrishnan, V. (6th June 2007)
    Structures of tRNAs with an expanded anticodon loop in the decoding center of the 30S ribosomal subunit.
    RNA 13(6): 817-23
  • Passmore, L.A., et al. (13th April 2007)
    The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome.
    Mol Cell 26(1): 41-50

2006

  • Selmer, M., et al. (29th September 2006)
    Structure of the 70S ribosome complexed with mRNA and tRNA.
    Science 313(5795): 1935-42

2005

  • Petry, S., et al. (29th December 2005)
    Crystal structures of the ribosome in complex with release factors RF1 and RF2 bound to a cognate stop codon.
    Cell 123(7): 1255-66
  • Daviter, T., Murphy, F.V., Ramakrishnan, V. (20th May 2005)
    Molecular biology. A renewed focus on transfer RNA.
    Science 308(5725): 1123-4
  • Ramakrishnan, V., Ogram, A.V., Lindner, A.S. (2005)
    Impacts of co-solvent flushing on microbial populations capable of degrading trichloroethylene.
    Environ Health Perspect 113(1): 55-61
  • Ogle, J.M., Ramakrishnan, V. (2005)
    Structural insights into translational fidelity.
    Annu Rev Biochem 74: 129-77

2004

  • Murphy, F.V., Ramakrishnan, V. (21st December 2004)
    Structure of a purine-purine wobble base pair in the decoding center of the ribosome.
    Nat Struct Mol Biol 11(12): 1251-2
  • Murphy, F.V., Ramakrishnan, V., Malkiewicz, A., Agris, P.F. (21st December 2004)
    The role of modifications in codon discrimination by tRNA(Lys)UUU.
    Nat Struct Mol Biol 11(12): 1186-91
  • Razeto, A., et al. (13th February 2004)
    Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain.
    J Mol Biol 336(2): 319-29

2003

  • Brodersen, D.E., Clemons, W.M., Carter, A.P., Wimberly, B.T., Ramakrishnan, V. (23rd November 2003)
    Phasing the 30S ribosomal subunit structure.
    Acta Crystallogr D Biol Crystallogr 59(Pt 11): 2044-50
  • Ogle, J.M., Carter, A.P., Ramakrishnan, V. (2003)
    Insights into the decoding mechanism from recent ribosome structures.
    Trends Biochem Sci 28(5): 259-66
  • Valle, M., Gillet, R., Kaur, S., Henne, A., Ramakrishnan, V., Frank, J. (4th April 2003)
    Visualizing tmRNA entry into a stalled ribosome.
    Science 300(5616): 127-30
  • Brodersen, D.E., Ramakrishnan, V. (2003)
    Shape can be seductive.
    Nat Struct Biol 10(2): 78-80

2002

  • Ogle, J.M., Murphy, F.V., Tarry, M.J., Ramakrishnan, V. (27th November 2002)
    Selection of tRNA by the ribosome requires a transition from an open to a closed form.
    Cell 111(5): 721-32
  • Ramakrishnan, V. (22nd February 2002)
    Ribosome structure and the mechanism of translation.
    Cell 108(4): 557-72
  • Brodersen, D.E., Clemons, W.M., Carter, A.P., Wimberly, B.T., Ramakrishnan, V. (22nd February 2002)
    Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: structure of the proteins and their interactions with 16 S RNA.
    J Mol Biol 316(3): 725-68
  • Arndt, J.W., Hao, B., Ramakrishnan, V., Cheng, T., Chan, S.I., Chan, M.K. (2002)
    Crystal structure of a novel carboxypeptidase from the hyperthermophilic archaeon Pyrococcus furiosus.
    Structure 10(2): 215-24

2001

  • Clemons, W.M., et al. (20th July 2001)
    Crystal structure of the 30 S ribosomal subunit from Thermus thermophilus: purification, crystallization and structure determination.
    J Mol Biol 310(4): 827-43
  • Ogle, J.M., Brodersen, D.E., Clemons, W.M., Tarry, M.J., Carter, A.P., Ramakrishnan, V. (4th May 2001)
    Recognition of cognate transfer RNA by the 30S ribosomal subunit.
    Science 292(5518): 897-902
  • Ramakrishnan, V., Moore, P.B. (2001)
    Atomic structures at last: the ribosome in 2000.
    Curr Opin Struct Biol 11(2): 144-54
  • Carter, A.P., et al. (19th January 2001)
    Crystal structure of an initiation factor bound to the 30S ribosomal subunit.
    Science 291(5503): 498-501
  • Brodersen, D.E., et al. (2001)
    Atomic structures of the 30S subunit and its complexes with ligands and antibiotics.
    Cold Spring Harb Symp Quant Biol 66: 17-32

2000

  • Brodersen, D.E., Clemons, W.M., Carter, A.P., Morgan-Warren, R.J., Wimberly, B.T., Ramakrishnan, V. (22nd December 2000)
    The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit.
    Cell 103(7): 1143-54
  • Wimberly, B.T., et al. (21st September 2000)
    Structure of the 30S ribosomal subunit.
    Nature 407(6802): 327-39
  • Carter, A.P., Clemons, W.M., Brodersen, D.E., Morgan-Warren, R.J., Wimberly, B.T., Ramakrishnan, V. (21st September 2000)
    Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics.
    Nature 407(6802): 340-8
  • Allard, P., et al. (15th August 2000)
    Another piece of the ribosome: solution structure of S16 and its location in the 30S subunit.
    Structure 8(8): 875-82
  • Shu, F., Ramakrishnan, V., Schoenborn, B.P. (11th April 2000)
    Enhanced visibility of hydrogen atoms by neutron crystallography on fully deuterated myoglobin.
    Proc Natl Acad Sci U S A 97(8): 3872-7

1999

  • Angus-Hill, M.L., Dutnall, R.N., Tafrov, S.T., Sternglanz, R., Ramakrishnan, V. (17th December 1999)
    Crystal structure of the histone acetyltransferase Hpa2: A tetrameric member of the Gcn5-related N-acetyltransferase superfamily.
    J Mol Biol 294(5): 1311-25
  • Clemons, W.M., Gowda, K., Black, S.D., Zwieb, C., Ramakrishnan, V. (24th September 1999)
    Crystal structure of the conserved subdomain of human protein SRP54M at 2.1 A resolution: evidence for the mechanism of signal peptide binding.
    J Mol Biol 292(3): 697-705
  • Clemons, W.M., May, J.L., Wimberly, B.T., McCutcheon, J.P., Capel, M.S., Ramakrishnan, V. (26th August 1999)
    Structure of a bacterial 30S ribosomal subunit at 5.5 A resolution.
    Nature 400(6747): 833-40
  • Wimberly, B.T., Guymon, R., McCutcheon, J.P., White, S.W., Ramakrishnan, V. (14th May 1999)
    A detailed view of a ribosomal active site: the structure of the L11-RNA complex.
    Cell 97(4): 491-502
  • McCutcheon, J.P., et al. (13th April 1999)
    Location of translational initiation factor IF3 on the small ribosomal subunit.
    Proc Natl Acad Sci U S A 96(8): 4301-6

1998

  • Zhou, Y.B., Gerchman, S.E., Ramakrishnan, V., Travers, A., Muyldermans, S. (24th September 1998)
    Position and orientation of the globular domain of linker histone H5 on the nucleosome.
    Nature 395(6700): 402-5
  • Dutnall, R.N., Tafrov, S.T., Sternglanz, R., Ramakrishnan, V. (21st August 1998)
    Structure of the histone acetyltransferase Hat1: a paradigm for the GCN5-related N-acetyltransferase superfamily.
    Cell 94(4): 427-38
  • Davies, C., Gerstner, R.B., Draper, D.E., Ramakrishnan, V., White, S.W. (17th August 1998)
    The crystal structure of ribosomal protein S4 reveals a two-domain molecule with an extensive RNA-binding surface: one domain shows structural homology to the ETS DNA-binding motif.
    EMBO J 17(16): 4545-58
  • Davies, C., Bussiere, D.E., Golden, B.L., Porter, S.J., Ramakrishnan, V., White, S.W. (19th June 1998)
    Ribosomal proteins S5 and L6: high-resolution crystal structures and roles in protein synthesis and antibiotic resistance.
    J Mol Biol 279(4): 873-88
  • Ramakrishnan, V., White, S.W. (1998)
    Ribosomal protein structures: insights into the architecture, machinery and evolution of the ribosome.
    Trends Biochem Sci 23(6): 208-12
  • Clemons, W.M., Davies, C., White, S.W., Ramakrishnan, V. (15th April 1998)
    Conformational variability of the N-terminal helix in the structure of ribosomal protein S15.
    Structure 6(4): 429-38
  • Dutnall, R.N., Tafrov, S.T., Sternglanz, R., Ramakrishnan, V. (1998)
    Structure of the yeast histone acetyltransferase Hat1: insights into substrate specificity and implications for the Gcn5-related N-acetyltransferase superfamily.
    Cold Spring Harb Symp Quant Biol 63: 501-7

1997

  • Dutnall, R.N., Ramakrishnan, V. (15th October 1997)
    Twists and turns of the nucleosome: tails without ends.
    Structure 5(10): 1255-9
  • Wimberly, B.T., White, S.W., Ramakrishnan, V. (15th September 1997)
    The structure of ribosomal protein S7 at 1.9 A resolution reveals a beta-hairpin motif that binds double-stranded nucleic acids.
    Structure 5(9): 1187-98
  • Ramakrishnan, V., Biou, V. (1997)
    [31] Treatment of multiwavelength anomalous diffraction data as a special case of multiple isomorphous replacement.
    Methods Enzymol 276: 538-557
  • Ramakrishnan, V. (1997)
    Histone H1 and chromatin higher-order structure.
    Crit Rev Eukaryot Gene Expr 7(3): 215-30
  • Ramakrishnan, V., Biou, V. (1997)
    Treatment of multiwavelength anomalous diffraction data as a special case of multiple isomorphous replacement.
    Methods Enzymol 276: 538-57
  • Ramakrishnan, V. (1997)
    Histone structure and the organization of the nucleosome.
    Annu Rev Biophys Biomol Struct 26: 83-112

1996

  • Hoffman, D.W., Cameron, C.S., Davies, C., White, S.W., Ramakrishnan, V. (20th December 1996)
    Ribosomal protein L9: a structure determination by the combined use of X-ray crystallography and NMR spectroscopy.
    J Mol Biol 264(5): 1058-71
  • Davies, C., Ramakrishnan, V., White, S.W. (15th September 1996)
    Structural evidence for specific S8-RNA and S8-protein interactions within the 30S ribosomal subunit: ribosomal protein S8 from Bacillus stearothermophilus at 1.9 A resolution.
    Structure 4(9): 1093-104
  • Goytisolo, F.A., Gerchman, S.E., Yu, X., Rees, C., Graziano, V., Ramakrishnan, V., Thomas, J.O. (1st July 1996)
    Identification of two DNA-binding sites on the globular domain of histone H5.
    EMBO J 15(13): 3421-9
  • Hamiche, A., Schultz, P., Ramakrishnan, V., Oudet, P., Prunell, A. (22nd March 1996)
    Linker histone-dependent DNA structure in linear mononucleosomes.
    J Mol Biol 257(1): 30-42
  • Jaishree, T.N., Ramakrishnan, V., White, S.W. (5th March 1996)
    Solution structure of prokaryotic ribosomal protein S17 by high-resolution NMR spectroscopy.
    Biochemistry 35(9): 2845-53
  • Davies, C., White, S.W., Ramakrishnan, V. (15th January 1996)
    The crystal structure of ribosomal protein L14 reveals an important organizational component of the translational apparatus.
    Structure 4(1): 55-66
  • Shu, F., Ramakrishnan, V., Schoenborn, B.P. (1996)
    High-level expression and deuteration of sperm whale myoglobin. A study of its solvent structure by X-ray and neutron diffraction methods.
    Basic Life Sci 64: 309-23
  • Graziano, V., Gerchman, S.E., Schneider, D.K., Ramakrishnan, V. (1996)
    Neutron scattering studies on chromatin higher-order structure.
    Basic Life Sci 64: 127-36

1995

  • Ramakrishnan, V. (5th December 1995)
    The histone fold: evolutionary questions.
    Proc Natl Acad Sci U S A 92(25): 11328-30
  • Biou, V., Shu, F., Ramakrishnan, V. (15th August 1995)
    X-ray crystallography shows that translational initiation factor IF3 consists of two compact alpha/beta domains linked by an alpha-helix.
    EMBO J 14(16): 4056-64
  • Kycia, J.H., Biou, V., Shu, F., Gerchman, S.E., Graziano, V., Ramakrishnan, V. (9th May 1995)
    Prokaryotic translation initiation factor IF3 is an elongated protein consisting of two crystallizable domains.
    Biochemistry 34(18): 6183-7
  • Ramakrishnan, V., et al. (1995)
    Structures of prokaryotic ribosomal proteins: implications for RNA binding and evolution.
    Biochem Cell Biol 73(11-12): 979-86

1994

  • Cerf, C., et al. (20th September 1994)
    Homo- and heteronuclear two-dimensional NMR studies of the globular domain of histone H1: full assignment, tertiary structure, and comparison with the globular domain of histone H5.
    Biochemistry 33(37): 11079-86
  • Davies, C., Gerchman, S.E., Kycia, J.H., McGee, K., Ramakrishnan, V., White, S.W. (1st September 1994)
    Crystallization and preliminary X-ray diffraction studies of bacterial ribosomal protein L14.
    Acta Crystallogr D Biol Crystallogr 50(Pt 5): 790-2
  • Gerchman, S.E., Graziano, V., Ramakrishnan, V. (1994)
    Expression of chicken linker histones in E. coli: sources of problems and methods for overcoming some of the difficulties.
    Protein Expr Purif 5(3): 242-51
  • Graziano, V., Gerchman, S.E., Schneider, D.K., Ramakrishnan, V. (24th March 1994)
    Histone H1 is located in the interior of the chromatin 30-nm filament.
    Nature 368(6469): 351-4
  • Hoffman, D.W., Davies, C., Gerchman, S.E., Kycia, J.H., Porter, S.J., White, S.W., Ramakrishnan, V. (1st January 1994)
    Crystal structure of prokaryotic ribosomal protein L9: a bi-lobed RNA-binding protein.
    EMBO J 13(1): 205-12

1993

  • Golden, B.L., Ramakrishnan, V., White, S.W. (15th December 1993)
    Ribosomal protein L6: structural evidence of gene duplication from a primitive RNA binding protein.
    EMBO J 12(13): 4901-8
  • Golden, B.L., Hoffman, D.W., Ramakrishnan, V., White, S.W. (30th November 1993)
    Ribosomal protein S17: characterization of the three-dimensional structure by 1H and 15N NMR.
    Biochemistry 32(47): 12812-20
  • Cerf, C., et al. (26th October 1993)
    Homo- and heteronuclear two-dimensional NMR studies of the globular domain of histone H1: sequential assignment and secondary structure.
    Biochemistry 32(42): 11345-51
  • Ramakrishnan, V., Finch, J.T., Graziano, V., Lee, P.L., Sweet, R.M. (18th March 1993)
    Crystal structure of globular domain of histone H5 and its implications for nucleosome binding.
    Nature 362(6417): 219-23

1992

  • Ramakrishnan, V., White, S.W. (27th August 1992)
    The structure of ribosomal protein S5 reveals sites of interaction with 16S rRNA.
    Nature 358(6389): 768-71

1991

  • Mangel, W.F., Lin, B.H., Ramakrishnan, V. (25th May 1991)
    Conformation of one- and two-chain high molecular weight urokinase analyzed by small-angle neutron scattering and vacuum ultraviolet circular dichroism.
    J Biol Chem 266(15): 9408-12
  • Ramakrishnan, V., Patthy, L., Mangel, W.F. (23rd April 1991)
    Conformation of Lys-plasminogen and the kringle 1-3 fragment of plasminogen analyzed by small-angle neutron scattering.
    Biochemistry 30(16): 3963-9
  • Ramakrishnan, V., Gerchman, S.E. (15th January 1991)
    Cloning, sequencing, and overexpression of genes for ribosomal proteins from Bacillus stearothermophilus.
    J Biol Chem 266(2): 880-5

1990

  • Graziano, V., Ramakrishnan, V. (20th August 1990)
    Interaction of HMG14 with chromatin.
    J Mol Biol 214(4): 897-910
  • Mangel, W.F., Lin, B.H., Ramakrishnan, V. (6th April 1990)
    Characterization of an extremely large, ligand-induced conformational change in plasminogen.
    Science 248(4951): 69-73
  • Graziano, V., et al. (20th March 1990)
    Crystallization of the globular domain of histone H5.
    J Mol Biol 212(2): 253-7
  • Ramakrishnan, V., Sinicropi, D.V., Dere, R., Darbonne, W.C., Bechtol, K.B., Baker, J.B. (15th February 1990)
    Interaction of wild-type and catalytically inactive mutant forms of tissue-type plasminogen activator with human umbilical vein endothelial cell monolayers.
    J Biol Chem 265(5): 2755-62

1988

  • Graziano, V., Gerchman, S.E., Ramakrishnan, V. (20th October 1988)
    Reconstitution of chromatin higher-order structure from histone H5 and depleted chromatin.
    J Mol Biol 203(4): 997-1007
  • Capel, M.S., Ramakrishnan, V. (1988)
    Neutron-scattering topography of proteins of the small ribosomal subunit.
    Methods Enzymol 164: 117-31

1987

  • Capel, M.S., et al. (4th December 1987)
    A complete mapping of the proteins in the small ribosomal subunit of Escherichia coli.
    Science 238(4832): 1403-6
  • Gerchman, S.E., Ramakrishnan, V. (1987)
    Chromatin higher-order structure studied by neutron scattering and scanning transmission electron microscopy.
    Proc Natl Acad Sci U S A 84(22): 7802-6

1986

  • Ramakrishnan, V., Graziano, V., Capel, M.S. (15th November 1986)
    A role for proteins S3 and S14 in the 30 S ribosomal subunit.
    J Biol Chem 261(32): 15049-52
  • Ramakrishnan, V. (28th March 1986)
    Distribution of protein and RNA in the 30S ribosomal subunit.
    Science 231(4745): 1562-4

1984

  • Wobbe, C.R., Mitra, S., Ramakrishnan, V. (18th December 1984)
    Structure of the capsid of Kilham rat virus from small-angle neutron scattering.
    Biochemistry 23(26): 6565-9
  • Ramakrishnan, V., Capel, M., Kjeldgaard, M., Engelman, D.M., Moore, P.B. (5th April 1984)
    Positions of proteins S14, S18 and S20 in the 30 S ribosomal subunit of Escherichia coli.
    J Mol Biol 174(2): 265-84
  • Donnelly, M.I., Hartman, F.C., Ramakrishnan, V. (10th January 1984)
    The shape of ribulose bisphosphate carboxylase/oxygenase in solution as inferred from small angle neutron scattering.
    J Biol Chem 259(1): 406-11
  • Moore, P.B., et al. (1984)
    Neutron scattering and the 30 S ribosomal subunit of E. coli.
    Basic Life Sci 27: 73-91

1983

  • Uberbacher, E.C., Ramakrishnan, V., Olins, D.E., Bunick, G.J. (11th October 1983)
    Neutron scattering studies of nucleosome structure at low ionic strength.
    Biochemistry 22(21): 4916-23
  • Ramakrishnan, V.R., Darszon, A., Montal, M. (25th April 1983)
    A small angle x-ray scattering study of a rhodopsin-lipid complex in hexane.
    J Biol Chem 258(8): 4857-60

1981

  • Ramakrishnan, V.R., Moore, P.B. (15th December 1981)
    Analysis of neutron distance data.
    J Mol Biol 153(3): 719-38
  • Ramakrishnan, V.R., Yabuki, S., Sillers, I.Y., Schindler, D.G., Engelman, D.M., Moore, P.B. (15th December 1981)
    Positions of proteins S6, S11 and S15 in the 30 S ribosomal subunit of Escherichia coli.
    J Mol Biol 153(3): 739-60

1980

  • Ramakrishnan, V., Darszon, A., Philipp, M., Montal, M. (1980)
    Rhodopsin in model membranes: the kinetics of channel opening and closing in rhodopsin-containing planar lipid bilayers.
    Ann N Y Acad Sci 358: 36-42

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