Our primary goal is to shed light on how cellular components are sorted and dispersed by microtubule-based motor complexes, and how these transport processes contribute to the functions of cells in situ (i.e. within organisms). We have long-standing interests in the cytoplasmic transport of mRNAs – a process that spatially controls protein function in cells – and principles of motor regulation. We use a combination of techniques, including genetics, time-lapse microscopy, biochemistry, structural biology and single molecule assays of cargo transport in vitro. Read more about our research here.
Click on the icons below for information about genome editing and outreach projects that were initiated in our lab:
