Marta shares her experience as a mother and a scientist, and how she has managed to balance these two facets of her life during the COVID-pandemic.
News
New publication: How does an increase in cell numbers affect mouse embryo development?
Mouse embryos are remarkably plastic. They show plasticity in the regulation of cell fate, cell number and tissue morphogenesis, but the mechanisms behind remain unknown. Here we show that mouse embryos respond to an increase in cell numbers by changing the dynamics and mechanism of embryonic morphogenesis. Read the entire story at:
https://www.sciencedirect.com/science/article/pii/S2213671120303799
New publication: How and when do aneuploid human embryos fail to develop?
Aneuploidy is the major limitation of human reproduction. However, the developmental consequences of specific aneuploidies remain unexplored. Here we analysed the post-implantation development of human embryos bearing common aneuploidies. Read the entire story at:
New review: Studying the mechanisms of our own development
Novel experimental tools are allowing us to explore the mechanisms of our own development. Here I discuss how cell fate specification events and tissue shape changes are coordinated during early human development. You can read the review at:
Marta has been awarded the International 3Rs prize
Our work using 3D cultures of mouse and human embryonic stem cells, and mouse and human embryo culture systems has been recognised for its impact on reduction, refinement and replacement of animals in research. You can read more at: