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Publications

2025

  • Sakata, R.C., Shahbazi, M.N. (2025)
    Building a molecular reference map of the human embryo.
    Nat Methods 22(1): 20-21

2024

  • Rosa, V.S., Sato, N., Shahbazi, M.N. (2024 )
    Protocol for generating a 3D culture of epiblast stem cells.
    STAR Protoc 5(4): 103347
  • Shahbazi, M.N., Pasque, V. (2024 )
    Early human development and stem cell-based human embryo models.
    Cell Stem Cell 31(10): 1398-1418
  • Makhlouf, A., Wang, A., Sato, N., Rosa, V.S., Shahbazi, M.N. (2024 )
    Integrin signaling in pluripotent cells acts as a gatekeeper of mouse germline entry.
    Sci Adv 10(36): eadk2252
  • Despin-Guitard, E., et al. (2024 )
    Non-apical mitoses contribute to cell delamination during mouse gastrulation.
    Nat Commun 15(1): 7364
  • Sato, N., et al. (2024 )
    Basal delamination during mouse gastrulation primes pluripotent cells for differentiation.
    Dev Cell 59(10): 1252-1268.e13

2023

  • Watson, J.L., et al. (2023 )
    Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells.
    Cell 186(21): 4710-4727.e35
  • Miroshnikova, Y.A., Shahbazi, M.N., Negrete, J., Chalut, K.J., Smith, A. (2023 )
    Cell state transitions: catch them if you can.
    Development 150(6)
  • Shahbazi, M.N. (2023)
    Size matters.
    Nat Rev Mol Cell Biol 24(1): 5

2022

  • Sharma, K., et al. (2022 )
    #ESHREjc report: renewing the old: novel stem cell research for unsolved ART problems.
    Hum Reprod 37(9): 2224-2227
  • Rosa, V.S., Shahbazi, M.N. (2022 )
    Human blastoids 3.0.
    Cell Stem Cell 29(1): 8-10

2021

  • Hiiragi, T., et al. (2021 )
    20 years of Developmental Cell: Looking forward.
    Dev Cell 56(23): 3185-3191
  • Mackinlay, K.M., et al. (2021 )
    An in vitro stem cell model of human epiblast and yolk sac interaction.
    Elife 10
  • Molè, M.A., et al. (2021 )
    A single cell characterisation of human embryogenesis identifies pluripotency transitions and putative anterior hypoblast centre.
    Nat Commun 12(1): 3679
  • Orietti, L.C., et al. (2021 )
    Embryo size regulates the timing and mechanism of pluripotent tissue morphogenesis.
    Stem Cell Reports 16(5): 1182-1196
  • Shahbazi, M.N. (2021 )
    Defining myself as a mother scientist.
    Cell Stem Cell 28(5): 796-798
  • Ruiz-Pinto, S., et al. (2021 )
    Regulatory CDH4 Genetic Variants Associate With Risk to Develop Capecitabine-Induced Hand-Foot Syndrome.
    Clin Pharmacol Ther 109(2): 462-470

2020

  • Lynch, C.J., et al. (2020 )
    Global hyperactivation of enhancers stabilizes human and mouse naive pluripotency through inhibition of CDK8/19 Mediator kinases.
    Nat Cell Biol 22(10): 1223-1238
  • Shahbazi, M.N., et al. (2020 )
    Developmental potential of aneuploid human embryos cultured beyond implantation.
    Nat Commun 11(1): 3987
  • Shahbazi, M.N. (2020 )
    Mechanisms of human embryo development: from cell fate to tissue shape and back.
    Development 147(14)

2019

  • Shahbazi, M.N., Siggia, E.D., Zernicka-Goetz, M. (2019 )
    Self-organization of stem cells into embryos: A window on early mammalian development.
    Science 364(6444): 948-951

2018

  • Shahbazi, M.N., Zernicka-Goetz, M. (2018 )
    Deconstructing and reconstructing the mouse and human early embryo.
    Nat Cell Biol 20(8): 878-887

2017

  • Shahbazi, M.N., et al. (2017 )
    Pluripotent state transitions coordinate morphogenesis in mouse and human embryos.
    Nature 552(7684): 239-243
  • Zhu, M., Leung, C.Y., Shahbazi, M.N., Zernicka-Goetz, M. (2017 )
    Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo.
    Nat Commun 8(1): 921
  • Shahbazi, M.N., Peña-Jimenez, D., Antonucci, F., Drosten, M., Perez-Moreno, M. (2017 )
    Clasp2 ensures mitotic fidelity and prevents differentiation of epidermal keratinocytes.
    J Cell Sci 130(4): 683-688

2016

  • Shahbazi, M.N., et al. (2016 )
    Self-organization of the human embryo in the absence of maternal tissues.
    Nat Cell Biol 18(6): 700-708

2015

  • Coelho, P.A., et al. (2015)
    Over-expression of Plk4 induces centrosome amplification, loss of primary cilia and associated tissue hyperplasia in the mouse.
    Open Biol 5(12): 150209
  • Shahbazi, M.N., Perez-Moreno, M. (2015 )
    Connections between cadherin-catenin proteins, spindle misorientation, and cancer.
    Tissue Barriers 3(3): e1045684

2014

  • Shahbazi, M.N., Perez-Moreno, M. (2014 )
    Microtubules CLASP to Adherens Junctions in epidermal progenitor cells.
    Bioarchitecture 4(1): 25-30

2013

  • Shahbazi, M.N., Megias, D., Epifano, C., Akhmanova, A., Gundersen, G.G., Fuchs, E., Perez-Moreno, M. (2013 )
    CLASP2 interacts with p120-catenin and governs microtubule dynamics at adherens junctions.
    J Cell Biol 203(6): 1043-61

2010

  • Villa-Morales, M., González-Gugel, E., Shahbazi, M.N., Santos, J., Fernández-Piqueras, J. (2010 )
    Modulation of the Fas-apoptosis-signalling pathway by functional polymorphisms at Fas, FasL and Fadd and their implication in T-cell lymphoblastic lymphoma susceptibility.
    Carcinogenesis 31(12): 2165-71

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© 2025 · Shahbazi Lab at the MRC Laboratory of Molecular Biology
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