Schafer lab Papers

Primary research articles:

2019

Anderson A, Chew YL, Schafer W, McMullan R (2019), "Identification of a conserved, orphan G-protein coupled receptor required for efficient pathogen clearance in C. elegans" Infect. Immun.

2018

Chew YL, Grundy LJ, Brown AEX, Beets I, Schafer WR (2018), "Neuropeptides encoded by nlp-49 modulate locomotion, arousal and egg-laying behaviours in C. elegans via the receptor SEB-3" Phil Trans R Soc B 373:  20170368.

Chew YL, Tanizawa Y, Cho Y, Zhao B, Yu AJ Ardiel EL, Rabinowitch I, Bai J, Rankin CH, Lu H, Beets I, Schafer WR (2018), "An afferent neuropeptide system transmits mechanosensory signals triggering sensitization and arousal in C. elegans” Neuron 99, 1233–1246
Dr Chew's interview at LMB

Javer A, Currie M, Hokanson J, Lee CW, Li K, Yemini E, Grundy LJ, Ch'ng QL, Schafer WR, Kerr R, Brown AEX (2018), "An open source platform for analysing and sharing worm behaviour data” Nat Meth 15: 645-646.

Cho Y, Oakland DN, Lee SA, Schafer WR, Lu H, "On-chip functional neuroimaging to mechanical stimulation in Caenorhabditis elegans larvae for studying functional role of neural circuits” Lab Chip 18: 601-609.

2017

Yan G, Vértes PE, Towlson EK, Chew YL, Walker DS, Schafer WR, Barabási A-L (2017), "Network control principles predict neuron function in the C. elegans connectome" Nature 550: 519-523.

Chew YL, Walker DS, Towlson EK, Vértes PE, Yan G, Barabási A-L, Schafer WR (2017), "Recordings of Caenorhabditis elegans locomotor behaviour following targeted ablation of single motorneurons"Sci Data 4: 170156.

Cho Y, Porto DA, Hwang H, Grundy LJ, Schafer WR, Lu H (2017), "Automated and controlled mechanical stimulation and functional imaging in vivo in C. elegans"Lab Chip 17: 2609-2618.

Giese APJ, Tang YQ, Sinha GP, Bowl MR, Goldring AC, Parker A, Freeman MJ, Brown SDM, Riazuddin S, Fettiplace R, Schafer WR, Frolenkov GI, Ahmed ZM. (2017), "CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells"Nat Commun 8:43

Hostettler L, Grundy L, Käser-Pébernard S, Wicky C, Schafer WR, Glauser DA (2017), "The bright fluorescent protein mNeonGreen facilitates protein expression analysis in vivo"G3 (Bethesda) 7: 607-615.

2016

Bentley B, Branicky RS, Barnes CL, Chew YL, Yemini E, Bullmore ET, Vértes PE, Schafer WR, "The multilayer connectome of Caenorhabditis elegans" Plos Comput Biol 12(12): e1005283.

Loucks CM, Bialas NJ, Dekkers MP, Walker DS, Grundy LJ, Li C, Inglis PN, Kida K, Schafer WR, Blacque OE, Jansen G, Leroux MR (2016), "PACRG, a Protein Linked to Ciliary Motility, Mediates Cellular Signaling" Mol Biol Cell 27(13):2133-44.

Ezcurra M, Walker DS, Beets I, Swoboda P, Schafer WR (2016), "Neuropeptidergic signaling and active feeding state inhibit nociception in C. elegans" J Neurosci 36: 3157-3169.

Rabinowitch I, Laurent P, Zhao B, Walker D, Beets I, Schoofs L, Bai J, Schafer WR, Treinin M (2016), "Neuropeptide-driven cross-modal plasticity following sensory loss in C. elegans" Plos Biol 14: e1002348.

2015

Schwarz RF, Branicky R, Grundy LJ, Schafer WR, Brown AEX (2015), "Changes in postural syntax underlie sensory modulation and natural variation of C. elegans locomotion" PLoS Comp Biol 11: e1004322.

Choi S, Taylor KP, Chatzigeorgiou M, Hu Z, Schafer WR, Kaplan JM (2015) , "Sensory neurons arouse C. elegans locomotion via both glutamate and neuropeptide release.” PLoS Genetics 11: e1005359

Rabinowitch I, Schafer WR (2015), "Engineering new synaptic connections in C. elegans.” Worm Epub 28 Jan 2015

Schafer WR (2015), "Mechanosensory molecules and circuits in C. elegans.” Pflügers Arch. 467: 39-48.

Butler VJ, Branicky R, Yemini E, Liewald JF, Gottschalk A, Kerr RA, Chklovskii DB, Schafer WR (2015), “A consistent muscle activation strategy underlies crawling and swimming in Caenorhabditis elegans.” J R Soc Interface 12(102):20140963

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Reviews/commentaries/book chapters:

2019

2018

Schafer WR (2018),"The worm connectome: back to the future" Trends Neurosci 41: 763-765.

Towlson EK, Vértes PE, Yan G, Chew YL, Walker DS, Schafer WR, Barabási A-L (2018),"Caenorhabditis elegans and the network control framework – FAQ" Phil Trans R Soc B: 373: 20170372.

2017

Walker DS, Chew YL, Schafer WR (2017),"Genetics of behavior in C. elegans" in The Oxford Handbook of Invertebrate Neurobiology (J Byrne, editor), Oxford University Press, Oxford UK.

Chew YL, Schafer WR (2017),"A network for swimming" Elife. 2017 Jul 5;6. pii: e28780. doi: 10.7554/eLife.28780

2016

Schafer WR (2016),"Nematode nervous systems" Curr Biol 26: R955-959.

Chew YL, Schafer WR (2016),"Dopamine helps worms deal with stress" EMBO J 35: 1851-1852.

2015

Rabinowitch I, Schafer WR (2015),"Engineering new synaptic connections in C. elegans" Worm Epub 28 Jan 2015.

Schafer WR (2015),"Mechanosensory molecules and circuits in C. elegans" Pflügers Arch. 467: 39-48.

Completed publication list from our lab