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cytoplasmic mRNA transport

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Our preprint on RNA-directed activation of dynein is available

13th March 2018

We’ve posted a preprint at bioRxiv describing in vitro reconstitution of mRNA transport. We use the system to reveal activation of dynein motility by an RNA localisation signal. Congratulations to Mark and his co-authors.

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We have a funded post-doc position available!

6th February 2018

Application deadline is 1st March 2018. Please see here for more details.

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Welcome to our new PhD student Florence Young!

29th October 2017

Florence has joined the lab to work on the formation, maturation and motility of mRNPs.

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Our work on LIS1’s regulation of end tracking and processive movement of dynein is published!

20th April 2017

Our work showing that LIS1 is a context- and concentration-dependent regulator of the human dynein complex is published. Read the paper here. Congratulations to all involved.

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Thi’s paper on mechanistic effects of dynein-1 disease mutations is published!

5th April 2017

Thi’s paper is available (open access) at PNAS.

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Mo and Simon’s SnapShot on mRNA localisation is out!

5th March 2017

The SnapShot is available here.

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David Salvador Garcia has started his PhD in the lab!

10th January 2017

A warm welcome to David, who joined us in October after a Masters degree in Basel.

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New lab publication!

19th May 2015

Fillip and Nadine’s paper on systematic evaluation of Drosophila CRISPR tools has been published. Congratulations!

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EMBO membership for Simon

14th May 2015

The work of the lab has been recognised by Simon’s election as a member of EMBO

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Mo and Nadine have joined the lab

14th August 2014

Mo and Nadine have joined the lab to work on mRNA transport and CRISPR genome engineering, respectively. Welcome!

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