We thank the MRC for long-term core funding support (since 1991) and CRUK for programme grant funding of our cancer-relevant work (since 2007). We are also grateful to AICR for project grant funding and to various UK and international funding bodies for awarding pre- and postdoctoral fellowships to members of my group. Thanks also to Greg Winter for mentorship and to Hugh Pelham for introducing me to the subtleties of the English language and the ways of running a Division. Last but not least, thanks to Maya and Beni for bearing with me at times when the lab had to come first.