The “cell” is the simplest living homeostatic unity with complex characteristics: identity, evolution, time, memory, communication, resilience. In general terms the cell can be thought as a simplified molecular ecosystem, where complex living behaviours arise from the interplay between organic and mechano-chemical elements, many of which comes from the environmental context.
The macromolecular basis of organelle shape and remodelling
Our lab searches for the ruling bio-physical and chemical principles which allow cellular life with a focus on the architecture of the nucleus, the main membrane compartment which transduce information. Broadly we aim to answer the following fundamental question:
How does compartment shape, function and movement emerge from macromolecules organisation?
We carry out both blue-sky and biomedicine research projects on the macromolecular basis of nuclear architecture and remodelling, and we develop new tools and algorithms to reach our goals and for a large community of scientists.
We work as an interdisciplinary and collaborative team of scientists whose goal is to produce high-quality research outputs.
