Pictured for day 58 of #LMB365 are the basal stress fibres of Caco-2 cells, a model for the epithelial cells that line the human colon. These stress fibres are made of bundles of the cytoskeletal protein actin (red) as well as the motor protein myosin (yellow) and vinculin (blue) that links these fibres to anchoring points in the plasma membrane. Jesse Peterson in Katja Röper’s lab in the Cell Biology Division uses these cells to study how tissues like the colon epithelium establish and maintain their critical barrier function.
MRC Laboratory of Molecular Biology
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