Author: University of Cambridge
Title: Sex, food and smell
Reference University of Cambridge 16 March 2016
Year: 2016
Type: Events and Celebrations
Subject: Greg Jefferis gives a talk at the University Technical College as part of the Cambridge Science Festival
Keywords: Greg Jefferis; pheromones; Cambridge Science Festival; University Technical College (UTC); talk; smells;
Photographs:Author: ADCOCK
Title: Case Study: Medical Research Council - Laboratory of Molecular Biology
Reference ADCOCK 8 October 2015
Year: 2015
Type: Architecture and Buildings
Subject: Adcock the refrigeration air conditioning company look at the work they were contracted to do on the new LMB building
Keywords: Adcock; new building; BMS system; case study; refrigeration; cold rooms
Photographs: Sign out the front of building; view of atriumAuthor: Research Horizons - University of Cambridge
Title: A Tangled Tale
Reference Research Horizons February 2016
Year: 2016
Type: Science
Subject: A look at Alzheimer’s disease research and how there is still no effective drug available.
Keywords: ‘dementia tsunami’; Alzheimer’s disease; ‘tangles’; ‘plaques’; Michel Goedert; ‘magic bullet’; tau protein; ‘neurostatins’; neurodegenerative; Carol Brayne; Chris Dobson; David Rubinsztein; beta-amyloid
Photographs:Author: MRC Life
Title: Scientific sabotage is the name of the game in ‘Lab Wars’
Reference MRC Life April/May 2016
Year: 2016
Type: Miscellaneous
Subject: New card game has been jointly created by the LMB’s Caezar Al-Jassar
Keywords: Caezar Al-Jassar; Kuly Heer; ‘Lab Wars’; game; sabotage; academic rivalry
Photographs:Author: MRC Life
Title: LMB highly commended at the Understanding Animal Research Openness Awards
Reference MRC Life February/March 2016
Year: 2016
Type: Awards & Prizes
Subject: The LMB’s Biological Services Group received a highly commended prize for its Named Persons posters at the second annual Openness Awards
Keywords: Understanding Animal Research (UAR); Biological Services Group; Named Persons poster; Openness Awards; 79th Paget Lecture; highly commended prize; animal welfare
Photographs: An example of the Named Persons poster; framed sketch, drawn by UAR’s Mia Rozenbaum, received by winnersAuthor: MRC Life
Title: Lifetime Achievement Award Winner - Sir Gregory Winter
Reference MRC Life February/March 2016
Year: 2016
Type: Awards & Prizes
Subject: Greg Winter receives a Lifetime Achievement Award at The SCRIP Awards
Keywords: Gregory Winter; Lifetime Achievement Award; The SCRIP Awards; Miles Jupp; Cambridge Antibody Technology; Humira; Domantis; Herceptin; antibodies; Bicycle Therapeutics; bicycle peptides
Photographs: Greg receiving his award from Glen e Vries, President at Medidata and Miles JuppAuthor: Rosenthal, Peter B.
Title: From high symmetry to high resolution in biological electron microscopy: a commentary on Crowther (1971) ‘Procedures for three-dimensional reconstruction of spherical viruses by Fourier synthesis from electron micrographs’
Reference Philosophical Translations B 19 April 2015
Year: 2015
Type: History - Reminiscences
Subject: Commentary on Tony Crowther’s key paper written to celebrate the 350th anniversary of the journal Philosophical Transactions of the Royal Society
Keywords: Tony Crowther; three-dimensional structure; Hugh Huxley; Aaron Klug; electron micrographs; macromolecular assemblies; X-ray crystallography; Tomato bushy stunt virus (TBSV); John Finch; Fourier; T4 bacteriophage; electron cryomicroscopy (cryoEM); Richard Henderson; Nigel Unwin; two-dimensional crystals; computational; tomogram; high-resolution; Jacques Dubochet
Photographs:Author: Le Moignan, Mick
Title: The New Master
Reference Once a Caian Michaelmas 2012
Year: 2012
Type: History - Reminiscences
Subject: Interview with Alan Fersht the new Master of Gonville & Caius college
Keywords: Alan Fersht; Master; Gonville & Caius; protein engineering; biotechnology; therapeutics; Francis Crick; Gregory Winter; cancer; Cesar Milstein
Photographs: Graduation, with wife, soon after their marriage; at Stanford; Daughter Naomi at her graduation;.his retirement as Director of the Centre for Protein Engineering; arriving at his surprise fiftieth birthday party at Caius; Alan with Rev Dr Jack McDonald toasting Cambridge’s success in the 2004 Boat RaceAuthor: Whipple, Tom
Title: Hawking leads 150 Royal Society scientists against Brexit
Reference The Times 10 March 2016
Year: 2016
Type: Funding
Subject: Article about the letter by 150 fellows from the Royal Society including LMB scientists, sent to The Times against Brexit and its possible effect on science funding.
Keywords: Stephen Hawking; Royal Society; Brexit; European Union (EU); Alan Fersht; Gregory Winter; Letter to the Editor; The Times
Photographs:Author: NC3Rs
Title: Mini-brains show great potential to replace animals in studying neurological diseases
Reference NC3Rs 29 March 2016
Year: 2016
Type: Awards & Prizes
Subject: Madeline Lancaster has recently won the annual NC3Rs 3Rs Prize for her work on the creation of brain organoids that mimic the developing human cerebrum
Keywords: “mini-brains”; NC3Rs; Madeline Lancaster; organoids; 3Rs Prize; cerebral; Matrigel matrix; GlaxoSmithKline; Alzheimer’s; Parkinson’s disease; microcephaly; “the year of the organoid”
Photographs: Madeline at the 3Rs Prize ceremonyAuthor: News Medical
Title: Cambridge Pharmaceutical Cryo-EM Consortium formed by FEI, five pharmaceutical companies, the Medical Research Council and the University of Cambridge
Reference News Medical 4 April 2016
Year: 2016
Type: Biotechnology
Subject: Sample preparation and data collection services on a cryo-transmission electron microscope (cryo-EM) will be provided to the consortium companies for early-stage drug discovery research
Keywords: FEI; Astex Pharmaceuticals; AstraZeneca; GlaxoSmithKline; Heptares Therapeutics; UCB; University of Cambridge; “Cambridge Pharmaceutical Cryo-EM Consortium”; drug discovery; Titan Krios; Nanoscience Centre; Richard Henderson; Relion; Sjors Scheres
Photographs:Author: The Institute of Cancer Research
Title: Artificial DNA could build new generation of cancer drugs
Reference The Institute of Cancer Research 12 April 2016
Year: 2016
Type: Science
Subject: Scientists have built the first 3D nano-sized objects using artificial DNA, which could be used to deploy cancer treatments inside tumour cells
Keywords: Xeno Nucleic Acids (XNA); microscopic pyramid; diamond; ‘packets’; 3D; nanostructures; The Institute of Cancer Research; tetrahedrons; octahedrons; electron microscopy; cancer; Phil Holliger
Photographs: 3D model from electron microscopy data of the artificial XNA polymersAuthor: PharmaTimes
Title: Allergan signs $3.3bn deal with Heptares
Reference PharmaTimes 10 April 2016
Year: 2016
Type: Biotechnology
Subject: Heptares Therapeutics, an LMB spin-out company, announces a deal with Allergan for development of novel treatments for neurological disorders, including Alzheimer’s disease.
Keywords: Allergan; Heptares; Pfizer; Sosei; M1; HTL9936; cognitive disorders; pharmacokietic profile; experimental neurological therapies
Photographs:Author: ScienceDaily
Title: Vital nutrient has key role in keeping body clocks running on time
Reference ScienceDaily 13 April 2016
Year: 2016
Type: Science
Subject: Magnesium – a nutrient found in many foods – helps control how cells keep their own form of time to cope with the natural environmental cycle of day and night
Keywords: Magnesium; body clocks; chronotherapy; John O’Neill; University of Edinburgh; internal clock; metabolism; circadian rhythms
Photographs:Author: Kruiniger, Sylvie
Title: Behind the picture: a tiny cell-killing drill
Reference MRC Insight 28 April 2016
Year: 2016
Type: Science
Subject: Christos Savva, from Electron Microscopy Facility scientist at th, talks about why understanding structures of important proteins could be the key to treating many different diseases
Keywords: ‘lysenin pore’; Christos Savva; ‘mushroom cap’; ‘stem; ’cryo-EM; pore-forming proteins; earthworm; prokaryotic; eukaryotic organisms
Photographs: Image of lysenin PoreAuthor: Highfield, Roger
Title: Ultimate molecular machine plays key role in superbug fight
Reference Science Museum 31 May 2016
Year: 2016
Type: Science
Subject: The ribosome is a complex biological machine that plays a central role in all living things and one that, according to Venki Ramakrishnan, could provide the key to combating the global scourge of antibiotic resistance.
Keywords: Venki Ramakrishnan; ribosome; RNA; amino acids; Ada Yonath; Thomas Steitz; synchrotron; ‘brain’; ‘heart’; 50S; Hay Festival; Royal Society; antibiotics
Photographs: Image of 30S component of ribosome; Venki speaking at the festivalAuthor: Elliott, Chris
Title: DNA discovery pioneer James Watson pays Cambridge tribute to colleague Francis Crick
Reference Cambridge News 10 June 2016
Year: 2016
Type: History - Reminiscences
Subject: James Watson returned to the LMB to deliver a special talk about Francis Crick, marking the centenary of Francis’ birth. Francis and Jim cracked the secret of the DNA structure in the MRC unit over 60 years ago
Keywords: James Watson; Francis Crick; Maurice Watkins; Cavendish Laboratory; Gonville & Caius College; Sydney Brenner; “the secret of life’; centenary Crick’s birth
Photographs: James Watson pictured at the LMB (LMB image)Author: Agha-Hossein, Michelle
Title: Soft Landings Project - The Medical Research Council
Reference BSRIA 16 June 2016
Year: 2016
Type: Architecture and Buildings
Subject: Details of the Soft Landings project for the new LMB building, including a summary of the building’s special features, the design and construction process and post occupancy evaluation
Keywords: Soft Landings Project; new building; The Queen; RMJM architects; BAM construction; “golden thread’; £212 million
Photographs: External shot of building; atrium, staff restaurant (LMB)Author: Elmes, John
Title: He & me - Interview with Richard Henderson
Reference Times Higher Education 16 June 2016
Year: 2016
Type: Awards & Prizes
Subject: The winner of the Copley Medal talks structural biology, fixing cars and sleeping soundly
Keywords: Richard Henderson; Copley Medal; Royal Society; Peter Higgs; Edinburgh; Europe; protein crystallography; biomolecules
Photographs: Richard holding model in officeAuthor: Pettorelli, Nathalie
Title: More emphasis on doing collaborative research: meet Nicola Smyllie
Reference Soapbox Science 23 June 2016
Year: 2016
Type: Events and Celebrations
Subject: Nicola Smyllie, postdoc in Neurobiology Division, took part in the Soapbox Science event in Cambridge Market Square talking about “Body clocks: rhythm of life”
Keywords: Nicola Smyllie; circadian rhythms; gender bias; Soapbox Science; body clocks; career in science
Photographs:Author: Pettorelli, Nathalie
Title: Make academia more family friendly: Meet Danielle Mersch
Reference Soapbox Science 28 June 2016
Year: 2016
Type: Events and Celebrations
Subject: Danielle Mersch, postdoc in Neurobiology Division, took part in the Soapbox Science event in Cambridge Market Square talking about “Decoding the fly brain”
Keywords: Danielle Mersch; Greg Jefferis; Soapbox Science; fly brain; career in science
Photographs:Author: Byrne, Michael
Title: Scientists Discover a Vulnerability in HIV’s Protective Shell
Reference Motherboard 10 August 2016
Year: 2016
Type: Science
Subject: A team of researchers, led by Leo James, has discovered a key feature used by the HIV virus to infect healthy cells without giving itself away and triggering a corresponding immune response
Keywords: Leo James; HIV; hexacarboxybenzene; virus; capsid; retroviruses; RNA; nucleotides; cytoplasm; immune response; pores; protective shell
Photographs:Author: Nichols, Hannah
Title: HIV: Newly discovered component could lead to more effective drug
Reference MNT 14 August 2016
Year: 2016
Type: Science
Subject: Collaborative research between Leo James’s group and colleagues at UCL has uncovered key components of HIV, which they believe could lead to new approaches for drugs to fight the infection
Keywords: Leo James; HIV; Retroviruses; virus; RNA; capsid; iris-like pores; immune system; hexacarboxybenzene; David Jacques; nucleotides; Inhibitor molecule
Photographs:Author: Chhetri, K. Raghav, Keller, J. Philipp
Title: Microscopy: Imaging far and wide
Reference eLIFE 23 September 2016
Year: 2016
Type: Science
Subject: A custom-built objective lens called the Mesolens allows relatively large biological specimens to be imaged with cellular resolution. It was developed by Brad Amos, LMB Emeritus scientist, and a team at the University of Strathclyde.
Keywords: Brad Amos; microscope; Gail McConnell; Strathclyde University; Mesolens; whole-embryo phenotyping; near-cellular resolution
Photographs: Imaging large samples with cellular resolution and the Mesolens microscopeAuthor: Media Team
Title: New drug target for asthma
Reference Wellcome Trust Sanger Insitute 29 September 2016
Year: 2016
Type: Science
Subject: A new therapeutic target for inflammatory diseases such as asthma and autoimmune disorders has been identified by scientists, Andrew McKenzie is a author on the paper, and comments on this latest development.
Keywords: Andrew McKenzie; PD-1; Innate Lymphoid Cells (ILC2); asthma; immune system; T cells; antibody drugs; inflammatory diseases; autoimmune disorders; Sanger Institute
Photographs: