Author: Haverhill Echo
Title: Noble effort as Haverhill band member wins science ‘Oscar’ for his life’s work
Reference Haverhill Echo 8 December 2016
Year: 2016
Type: Awards & Prizes
Subject: The Haverhill Echo celebrates local resident Richard Pannell’s MRC Lifetime Achievement Award.
Keywords: Richard Pannell; Sir John Savill; national award; lifetime achievement award; Cesar Milstein; Haverhill Silver Band
Photographs: Richard Pannell in labAuthor: Commissariat, Tushna; Johnston, Hamish
Title: LIGO’s gravitational-wave discovery is Physics World 2016 Breakthrough of the Year
Reference Physicsworld.com 12 December 2016
Year: 2016
Type: Events and Celebrations
Subject: Work by Gail McConnell and LMB Emeritus, Brad Amos and colleagues at the University of Strathclyde have been selected for Physics World’s Top Ten Breakthroughs of 2016.
Keywords: Physics World; Breakthrough of the Year; Brad Amos; microscope lens; 3D images; confocal; radical; high resolution; mesolens
Photographs: Image of mouse embryoAuthor: Dovey, Dana
Title: HIV Research Breakthroughs 2016: How Close We’ve Come To A Cure, And Better Treatments
Reference Medical Daily 16 December 2016
Year: 2016
Type: Science
Subject: Medical Daily includes work by the LMB’s Leo James’s group and University College London on improving antiviral drugs as one of its HIV research breakthroughs of 2016
Keywords: HIV; CRISPR/Cas9 gene editing technique; antiviral; vaccine; virus; antiretroviral treatment (ART); Leo James; South Africa; HVTN 702
Photographs: Image of the virusAuthor: Bobrowska, Anna
Title: Cell scientist to watch - Madeline Lancaster
Reference Journal of Cell Science 4 January 2017
Year: 2017
Type: Career Structure
Subject: Madeline Lancaster, group leader in the LMB’s Cell Biology Division, is interviewed by the Journal of Cell Science and describes her impetus to pursue a career in science, discusses starting her own lab at the LMB and talks about her current research.
Keywords: Madeline Lancaster; microcephaly; macrocephaly; mutations; in vitro; organoids; brain; 3D; epithelial-derived organs; mesoderm-derived tissues; tissue engineering
Photographs: Madeline with the lab in the background; Madeline skiing in the U.S.Author: Mukhopadhyay, Rajendrani
Title: A chain of events: Linear ubiquitin chains, whose very existence once debated, now known to play a critical role in an inflammatory disease, thanks to the discovery of an enzyme
Reference ASBMB Today 5 January 2017
Year: 2017
Type: Science
Subject: David Komander’s group are amongst a group of scientists researching the enzymes of the ubiquitin system, which has already shown how mutations in the gene for OTULIN, an enzyme belonging to the OTU family of deubiquitinases, cause a rare systemic inflammatory disease
Keywords: David Komander; Rune Damgaard; Andrew McKenzie; FAM105B; enzymes; OTULIN; ubiquitin; LUBAC; mutations; inflammation; deubiquitinase; Met1-linked chains; NF-κB
Photographs:Author: University of Cambridge Research
Title: Dementia: Catching the memory thief
Reference University of Cambridge Research News 18 January 2017
Year: 2017
Type: Science
Subject: New film describing some of the progress now being made against this devastating disease, includes commentary from Michel Goedert, group leader in the Neurobiology Division, who discovered how tau fibres twist together to form tangles, a hallmark of Alzheimer’s, a type of dementia
Keywords: Alzheimer’s disease; Michel Goedert; ‘dementia tsunami’; ‘tangles’; ‘plaques’; beta-amyloid; ‘neurostatins’; ‘memory thief’; nerodegenerative disease; European Grand Prix; ‘magic bullet’
Photographs:Author: Bowman Rogers, Madolyn
Title: Antibodies Co-Opt Anti-Microbial Response to Clear Intraneuronal Tau
Reference ALZFORUM 13 January 2017
Year: 2017
Type: Science
Subject: Leo James and Michel Goedert, group leaders, recently published work in PNAS providing an explanation for how therapeutic antibodies eliminate pathogenic forms of tau protein. Here, Alzforum explore the background, results and implications of this study.
Keywords: Michel Goedert; Leo James; TRIM21; tau; William McEwan; HEK293; antibodies; neuroblastoma cell line; SHSY-5Y; cytosolic protein; virus; PNAS
Photographs:Author: Wiley
Title: The 16th Annual Wiley Prize in Biomedical Sciences Awarded for Pioneering Developments in Electron Microscopy
Reference Wiley Newsroom 22 February 2017
Year: 2017
Type: Awards & Prizes
Subject: The 16th annual Wiley Prize in Biomedical Sciences was awarded to Joachim Frank, Richard Henderson, and Marin van Heel for pioneering developments in electron microscopy that are transforming structural studies of biological molecules and their complexes
Keywords: Joachim Frank; Richard Henderson; Marin van Heel; Wiley Foundation; electron microscopy; Wiley Prize; $50,000; The Rockefeller University; Biomedical Sciences
Photographs:Author: University of Cambridge
Title: Life through a lens
Reference Cambridge Science Festival 27 February 2017
Year: 2017
Type: Events and Celebrations
Subject: Brad Amos gave a talk at the UTC Cambridge as part of the Cambridge Science Festival
Keywords: Brad Amos; Cambridge Science Festival; 3D images; subcellular; Mesolens
Photographs: Brad in the labAuthor: University of Cambridge
Title: Finding the fountain of youth: why we age and what we can do about it
Reference Cambridge Science Festival 28 February 2017
Year: 2017
Type: Events and Celebrations
Subject: Rebecca Taylor gave a talk at the UTC Cambridge as part of the Cambridge Science Festival. Rebecca explains how her lab are using worms to understand how the nervous system coordinates the ageing process, and how it controls the health of cells as we get older
Keywords: Rebecca Taylor; Cambridge Science Festival; nervous system; ageing process; worms; fountain of youth
Photographs:Author: Protein Data Bank in Europe
Title: Bringing Artists and Scientists Together Creates Very Exciting Results
Reference Protein Data Bank in Europe 6 March 2017
Year: 2017
Type: Exhibitions
Subject: Vivian, student artist who created a painting based on lysenin during Protein Data Bank in Europe’s art-science collaborative project, met with LMB’s Christos Savva, the scientist who discovered the structure of lysenin
Keywords: The Leys School; PDBe; lysenin; garden earthworm; art; Christos Savva; Michaelhouse Gallery; Vivian; 3D protein structures; exhibition; toxin; Protein Data Bank (PDB)
Photographs: Vivian and Christos standing in front of her paintingAuthor: Mazur, Suzan
Title: Julian Gough on SUPERFAMILY & Open Science
Reference The Huffington Post 13 March 2017
Year: 2017
Type: Science
Subject: Julian Gough is interviewed by the Huffington Post and discusses SUPERFAMILY, his database of structural and functional annotations for proteins and genomes, a public resource which scientists around the world can use freely in their research.
Keywords: Julian Gough; SUPERFAMILY; genomes; Tree of Life; protein domains; Cyrus Chothia; Michael Levitt; BioEssays; Genetrainer; computational prediction; database; Alexey Murzin; Protein Data Bank (PDB); Max Perutz; myoglobin; protein x-ray crystallography; Structural Classification of Proteins (SCOP); viruses; InterPro database
Photographs: Image of Julian GoughAuthor: University of Cambridge Research
Title: Visualising the genome: researchers create first 3D structure of active DNA
Reference University of Cambridge Research News 16 March 2017
Year: 2017
Type: Science
Subject: Tim Stevens, in collaboration with scientists from the University of Cambridge, has determined the first 3D structures of intact mammalian genomes from individual cells, showing how the DNA from all the chromosomes intricately folds to fit together inside the cell nuclei.
Keywords: Mammalian genomes; 3D structures; ‘master cells’; chromosomes; Tim Stevens; Ernest Laue; nuclear lamina; nuclei
Photographs:Author: Cambridge News
Title: PhD student Cara presents work to MPs
Reference Cambridge News 15 March 2017
Year: 2017
Type: Events and Celebrations
Subject: Cara Ellison a PhD student at the LMB takes part in the Stem (Science Technology, Engineering and Maths) for Britain event at Westminster
Keywords: Cara Ellison; Westminster; PhD Student; Parliament; MPs; bacteria; viruses; shortlisted; Scientific Committee
Photographs: Cara in the labAuthor: Medical Research Council
Title: Researchers create first 3D structures of active DNA
Reference Medical Research Council 13 March 2017
Year: 2017
Type: Science
Subject: Scientists, have determined the first 3D structures of intact mammalian genomes from individual cells, showing how the DNA from all the chromosomes intricately folds to fit together inside the cell nuclei.
Keywords: Mammalian genomes; 3D structures; ‘master cells’; chromosomes; Tim Stevens; Ernest Laue; nuclear lamina; nuclei
Photographs:Author: Welch, George
Title: Student shares data on research to parliament
Reference Oxfordshire Guardian 20 March 2017
Year: 2017
Type: Events and Celebrations
Subject: Cara Ellison a PhD student at the LMB takes part in the STEM (Science Technology, Engineering and Maths) for Britain event at Westminster
Keywords: Cara Ellison; STEM; Oxfordshire; Stephen Metcalfe MP; PhD Student; Westminster; bacteria; viruses; Parliament; Scientific Committee
Photographs: Cara pictured at the event with Ed Valzey MPAuthor: Sutton, Mike
Title: The chemist with x-ray vision
Reference Chemistry World 24 February 2017
Year: 2017
Type: History - Reminiscences
Subject: Mike Sutton tells the tale of John Kendrew and his work towards the unveiling of protein structures
Keywords: John Kendrew; Cavendish Laboratory; Lawrence Bragg; Max Perutz; Francis Crick; James Watson; Linus Pauling; radar; Air Ministry; John Desmond Bernal; x-ray crystallography; Dorothy Hodgkin; Fourier synthesis; Patterson function; haemoglobin; myoglobin; atom; Edsac I; Royal Society; Royal Medal; The thread of life; European Molecular Biology Laboratory (EMBL); Peterhouse Colege; Oxford; UN; knighthood; RAF; wing commander
Photographs: John Kendrew in forest of rods (MRC-LMB); Model of myoglobinAuthor: Harrison, Stephen C.
Title: Book Review: From Durban to the World
Reference Cell 26 January 2017
Year: 2017
Type: Book Review
Subject: Review of Kenneth Holmes book Aaron Klug - A Long Way From Durban: A Biography
Keywords: Aaron Klug; Kenneth Holmes; “A long way from Durban”; Royal Society; Birkbeck College; J.D. Bernal; Rosalind Franklin; Francis Crick; Max Perutz; tobacco mosaic virus (TMV); Cape Town; John Finch; Liebe; Peterhouse College; zinc fingers; viruses; tRNA; book review
Photographs:Author: Cambridge Business
Title: What’s it all about for AstraZeneca?
Reference Cambridge Business February 2017
Year: 2017
Type: Biotechnology
Subject: A look at how AstraZeneca is embedding itself in the community before it moves in to its new headquarters
Keywords: AstraZeneca; Cambridge Biomedical Campus; Cambridge Antibody Technology (CAT); MedImmune; Humira; Menelas Pangalos; Hugh Pelham; biotechnology; Cambridge Science Centre; Cancer Research UK; Science on display
Photographs: Cindy Forde and Jane Osbourn at the Cambridge Science Centre; The Cancer Research UK MedImmune Alliance Laboratory; artist drawing of new R&D centreAuthor: Benke, Michael
Title: Cara Ellison, a former pupil at Ss Helen and Katharine School in Abingdon, will present her Cambridge PhD research on antibiotic resistance
Reference The Oxford Times 13 March 2017
Year: 2017
Type: Events and Celebrations
Subject: Cara Ellison who went to school in Oxford takes part in the STEM (Science Technology, Engineering and Maths) for Britain event at Westminster
Keywords: Cara Ellison; PhD Student: STEM; Parliament; MPs; competition; antibiotic resistance; Scientific Committee
Photographs: Cara in the labAuthor: Finch, John
Title: The discovery of the double helix: a brief history of the MRC Laboratory of Molecular Biology
Reference School Sciences Review March 2003
Year: 2003
Type: History - Reminiscences
Subject: The DNA double helix and the first 3-D structures of proteins were worked out in an MRC unit housed in the Cavendish Laboratory in Cambridge. Its success has continued in the LMB, built in 1962 to accommodate its growing number of researchers
Keywords: Lawrence Bragg; Cavendish Laboratory; J.D. Bernal; Max Perutz; Dorothy Hodgkin; John Kendrew; Francis Crick; Sir Edward Mellanby; Caius College; myoglobin; haemoglobin; ‘Sage’; ‘Pykrete’; radar; James Watson; Michael Fuller; Sydney Brenner; Fred Sanger; Linus Pauling
Photographs: Max Perutz; John Kendrew building the first model of a protein (myoglobin) (MRC-LMB); Watson & Crick with double helical model of DNA; Mike Fuller in his office; The “Hut’ at the Cavendish Lab.Author: Cambridge Daily News
Title: Nobel theory was discussed in ‘pub’
Reference Cambridge Daily News 1962
Year: 1962
Type: Awards & Prizes
Subject: Francis Crick interview in which he talks about being awarded the Nobel Prize and how he and James Watson came to their discovery.
Keywords: Francis Crick; James Watson; Cavendish Laboratory; pub; Caius College; Admiralty; magnetic and accoustic mines; Portugal Place
Photographs: Francis Crick in seated in front of blackboardAuthor: Doherty, Peter
Title: Cream rises to the top
Reference Times Higher Education 30 September 2015
Year: 2015
Type: Laboratory Culture
Subject: LMB is mentioned in article about leadership required to enable universities to tackle today’s challenges, and the one rule that applies: quality is everything
Keywords: research culture; “float like a butterfly, sting like a be”; Janelia Research Campus; funding; strong institutions
Photographs:Author: Tozer, Adam
Title: Astrocytes Set the Pace of Our Body Clocks
Reference Technology Networks 22 March 2017
Year: 2017
Type: Science
Subject: The Hasting’s group reported their discovery of an entirely unprecedented component of the pacemaker of our body clock
Keywords: Michael Hastings; hypothalamus; Marco Brancaccio; Astrocytes; glial cells; GABAergic; glutamate; NR2C; Circadian rhythm; pacemaker; gliotransmitter; sleep/week cycle; body clock; Neuron
Photographs:Author: Artlyst
Title: Latest HIV Research Inspires Compelling New Art Collaboration
Reference Artlyst 3 April 2017
Year: 2017
Type: Exhibitions
Subject: Collaborative work between Leo James’ group in the PNAC Division and Greg Towers at UCL, has led to the discovery that HIV uses capsid pores to import nucleotides and evade innate immunity, and has inspired a new artistic project.
Keywords: Greg Towers; John Walter; Leo James; HIV/AIDS; artist; capsid; immune system; viral; UCL; exhibition; virus
Photographs: Artist John Walter with his work titled CAPSID