Author: Dubach, Isabelle
Title: Breakthrough study shows how HIV is shielded from immune attack
Reference UNSW News 10 July 2018
Year: 2018
Type: Science
Subject: Scientists from UNSW Sydney and the LMB have discovered that the human immunodeficiency virus (HIV) hijacks a small molecule from the host cell to protect itself from being destroyed by the host’s immune system.
Keywords: antiviral therapy; HIV; capsid; Leo James; virus; UNSW;inositol hexakisphosphate
Photographs:Author: Brackley, Paul
Title: Cambridge scientists discover why drinking alcohol increases your risk of cancer
Reference Cambridge Independent 4 January 2018
Year: 2018
Type: Science
Subject: Researchers at the LMB have helped to explain why drinking alcohol increases your risk of cancer
Keywords: Alcohol; cancer; ‘Dry January’; DNA; acetaldehyde; KJ Patel; damage; aldehyde dehydrogenases (ALDH); mutations
Photographs:Author: Brackley, Paul
Title: Crescendo Biologics pioneers a new approach to using antibodies in fight against cancer
Reference Cambridge Independent 23 June 2018
Year: 2018
Type: Biotechnology
Subject: Crescendo Biologics is a company that is taking the early antibody research of Georges Köhler, César Milstein and Greg Winter and applying further innovation to create cancer drugs
Keywords: Crescendo Biologics; Humabody; Humira; Greg Winter; Cambridge Antibody Technology (CAT); Peter Pack; antigens; Fab; ‘humanising’; VH domains; immunogloblins; cancer drugs; Georges Köhler; César Milstein; monoclonal antibodies; Michael Neuberger; Campath; therapeutic
Photographs:Author: The Pelican (Corpus Christi magazine)
Title: Dr Richard Henderson (m1966) Honorary Fellow and Nobel Prize winner
Reference The Pelican 2018
Year: 2018
Type: History - Reminiscences
Subject: Richard Henderson looks back over his life and scientific career
Keywords: Richard Henderson; Max Perutz; John Kendrew; Nigel Unwin; X-ray crystallography; David Blow; chymotrypsin; Director; electron microscopy; Nobel;
Photographs: Two images of Richard holding models; Richard receiving the Nobel PrizeAuthor: Guyoncourt, Sally
Title: ‘Drinking alcohol damages DNA and raises cancer risk’
Reference The i 4 January 2018
Year: 2018
Type: Science
Subject: KJ Patel has led a study into how drinking alcohol increases your risk of cancer
Keywords: KJ Patel; cancer; DNA; ethanol; damage; alcohol; acetaldehyde
Photographs:Author: Sansom, Clare
Title: A splice of life
Reference Chemistry World 23 March 2020
Year: 2020
Type: Science
Subject: History of spliceosome research and its importance, focusing on the work of Kiyoshi Nagai and his group.
Keywords: Human Genome Project; RNA; eukaryotes; Kiyoshi Nagai; Max Perutz; “Nobel Prize factory’; Chris Oubridge; Aaron Klug; haemoglobin; sliceosome; snRNPS (‘snurps’); Shaoxia Chen; Krios; introns; splicing; spinal muscular atrophy (SMA); X-ray crystallography
Photographs:Author: Brackley, Paul
Title: Are some people at greater genetic risk from Covid-19? MRC Laboratory of Molecular Biology seeks DNA volunteers
Reference Cambridge Independent 15 May 2020
Year: 2020
Type: Science
Subject: Cambridge Independent feature story on Julian Gough’s new phenotype prediction genome data study, which is also exploring whether DNA genotype can be used to predict Covid-19 risk factors. Julian is asking those who have had consumer DNA tests to aid the research by volunteering their data
Keywords: Covid-19; Julian Gough; 23andMe; AncestryDNA; genotype; risk factors; genetic; coronavirus; SARS-CoV-2 virus; ACE2 gene; immune system; BAME; ethnic groups
Photographs: Julian Gough in the lab (MRC LMB)Author: Highfield, Roger
Title: Coronavirus: How the virus works
Reference Science Museum Group 22 May 2020
Year: 2020
Type: Science
Subject: Science Museum blog: The development of COVID-19 treatments, tests, drugs and vaccines will be accelerated by molecular understanding of the COVID-19 virus. Roger Highfield, Science Director, looks at what is happening in the LMB
Keywords: COVID-19; SARS-CoV-2; Yorgo Modis; ‘Nobel prize factory’; virus; coronavirus; electron microscopy; Richard Henderson; cryo-EM; X-ray crystallography; John Briggs; Andrew Carter; Leo James; Sjors Scheres; cells; ‘non-structural protein’ (NSP); RNA; Sean Munro; ACE2; spike; polyprotein; Julian Sale; immune response; Jan Löwe; Radu Aricescu; Harvey McMahon; David Barford; John Sutherland; antibodies; Avigan; Remdesivir; Chris Oubridge; Felix Randow; Lori Passmore; Venki Ramakrishnan; Phil Holliger; phages; Madeline Lancaster; ‘mini brains’; organoids; Julian Gough; risk factors; genetics; genotype; protein reagents
Photographs:Author: The American Philosophical Society
Title: The American Philosophical Society Welcomes New Members for 2020
Reference The American Philosophical Society blog 5 May 2020
Year: 2020
Type: Awards & Prizes
Subject: The American Philosophical Society welcomes Venki Ramakrishnan as a new 2020 Member elected to the Society
Keywords: The American Philosophical Society; Venki Ramakrishnan; member
Photographs:Author: Callaway, Ewen
Title: Revolutionary Microscopy Technique Sees Individual Atoms
Reference Nature 4 June 2020
Year: 2020
Type: Science
Subject: Sjors Scheres’ and Radu Aricescu’s groups have pushed the boundaries of cryo-EM, allowing the technique to detect individual atoms in a protein for the first time
Keywords: cryo-EM; Sjors Scheres; Radu Aricescu; X-ray crystallography; histamine; 3D
Photographs:Author: Vienna BioCenter
Title: Researchers develop “quick and easy” Covid-19 test for population screening with simple means
Reference Vienna BioCenter 24 June 2020
Year: 2020
Type: Science
Subject: Max Kellner, a PhD student in Madeline Lancaster’s group, was stranded in Vienna as much of Europe went into lockdown at the start of the pandemic, but was able to join the Vienna COVID-19 Diagnostics Initiative
Keywords: SARS-CoV-2; Vienna BioCenter; Covid-19; Max Kellner; test; RT-LAMP; lockdown; VCDI (Vienna Covid-19 Diagnostics Initiative); rapid; screening
Photographs: Max Kellner with researchers from other institutes who joined together to develop the testAuthor: Keane, Sarah
Title: Dr. Kelly Nguyen
Reference RNA Society 3 July 2020
Year: 2020
Type: Career Structure
Subject: RNA Society Spotlight has a feature on Kelly Nguyen, a Group Leader in the Structural Studies Division. Kelly describes the inspirations that led to her working in RNA structural biology, her experience of starting her group, and her advice for younger scientists
Keywords: Kelly Nguyen; Tom Steitz; Kiyoshi Nagai; Jade Li; cryo-EM; telomerase structure; mentor; Davos; RNA Society
Photographs: Kelly in the lab (MRC LMB)Author: Brackley, Paul
Title: The origin of life on Earth explored at MRC LMB in Cambridge using a flask and a lamp
Reference Cambridge Independent 3 July 2020
Year: 2020
Type: Science
Subject: Nicholas Green is interviewed in the Cambridge Independent about John Sutherland’s group’s recent research suggesting that DNA and RNA building blocks might have co-existed at the dawn of life
Keywords: UV lamp; primordial soup; Nicholas Green; Jianfeng Xu; Václav Chmela; David Russell; John Sutherland; amino acids; RNA; flasks; Earth; synthetic biology; artificial life
Photographs: John Sutherland’s group outside the from of the buildingAuthor: Chalmers, Vanessa
Title: Scientists create a drug that ‘repairs damage to the brain and spinal cord’ in potential breakthrough for paralysed patients and Alzheimer’s sufferers
Reference Mail Online 28 August 2020
Year: 2020
Type: Science
Subject: A team led by Radu Aricescu’s group created a synthetic compound that acts like a ‘bridge’ where connections have been lost due to damage or illness, offering hope of new therapies for a range of devastating conditions, from Alzheimer’s disease to epilepsy
Keywords: Cerebellin-1, CPTX; Alzheimer’s disease; Radu Aricescu; brain; neuronal cells; neurodegeneration; synaptic; spinal cord; regenerate; ‘cut and paste’; epilepsy
Photographs:Author: Ferro, Diana
Title: Dr. Jailson Brito Querido
Reference RNA Society 22 September 2020
Year: 2020
Type: Career Structure
Subject: RNA Society Spotlight features Jailson Brito Querido, a postdoctoral researcher in Venki Ramakrishnan’s group. Jailson describes how he became interested in RNA biology, why he wanted to come to the LMB, and who his scientific hero is
Keywords: Jailson Brito Querido; Venki Ramakrishnan; RNA Society; Marie Curie; helcases; translation; elF4A; career
Photographs: Jailson Brito Querido in Lab (MRC LMB)Author: Biochemical Society
Title: Professor Kim Nasmyth awarded the 2021 Centenary Award by Biochemical Society
Reference Biochemical Society 25 March 2020
Year: 2020
Type: Alumni - Awards & Prizes
Subject: Kim, who is currently the Whitley Chair at the Department of Biochemistry, University of Oxford and a fellow of Trinity College is a former member of LMB, has made hugely valuable contributions to the life sciences. He has been awarded the Biochemistry Society Centenary Award for 2021.
Keywords: Kim Nasmyth; Biochemistry Society Centenary Award; alumni; cell biology
Photographs: Head shot of Kim NasmythAuthor: University of Cambridge News
Title: Tackling COVID-19: Dr Sarah Caddy
Reference University of Cambridge 26 June 2020
Year: 2020
Type: Alumni - Science
Subject: Sarah Caddy is interviewed about her work on COVID-19 during the pandemic and extending her work with Leo James’ group on how antibodies neutralise rotavirus and influenza to include coronaviruses
Keywords: Sarah Caddy; Alumni; COVID-19; SARS-CoV-2; coronavirus; antibody; vaccines; pets; Ebola; Leo James
Photographs: Sarah Caddy in the labAuthor: National Academy of Sciences News
Title: National Academy of Sciences Elects New Members
Reference National Academy of Sciences 27 April 2020
Year: 2020
Type: Alumni - Awards & Prizes
Subject: The National Academy of Sciences of the USA recognises distinguished and continuing achievements in original scientific research by election to membership and has recently elected 120 members and 26 international members including Anthony Hyman
Keywords: Anthony Hyman; alumni; Nation Academy of Sciences USA; Newly elected; award; Director; Max Planck Institute of Molecular Cell Biology and Genetics; member
Photographs:Author: Royal Microscopical Society
Title: Yanlan Mao is awarded the 2021 Royal Microscopical Society Medal for Life Sciences
Reference Royal Microscopical Society 6 August 2020
Year: 2020
Type: Alumni - Awards & Prizes
Subject: Yanlan Mao, who did her PhD with Matthew Freeman’s group in Cell Biology Division, has been awarded the RMS Medal for Life Sciences in recognition of her important contribution to our understanding of how cells and tissues are shaped and organised during the developmental process
Keywords: Yanlan Mao; Royal Microscopical Society Medal; alumni; award; Matthew Freeman; winner; Life Sciences
Photographs: Head Shot of YanlanAuthor: The Lister Institute of Preventative Medicine of
Title: Hayley Sharpe wins a 2020 Lister Institute Research Prize
Reference The Lister Institute 13 August 2020
Year: 2020
Type: Alumni - Awards & Prizes
Subject: Hayley Sharpe, a former PhD student with Sean Munro’s group in the Cell Biology Division, is one of four researchers to be awarded a 2020 Lister Institute Research Prize
Keywords: Hayley Sharpe; alumni; Lister Institute Research Prize; The Babraham Institute; tyrosine; phosphatase signalling; research
Photographs: Head shot of HayleyAuthor: White, John; Bretscher Mark S.
Title: Sydney Brenner. 13 January 1927-5 April 2019
Reference Biographical Memoirs of Fellows of the Royal Society
Year: 2020
Type: Alumni - Obituary
Subject: Memoir for Sydney Brenner written by John White and Mark Bretscher for the Royal Society
Keywords: Sydney Brenner; obituary; alumni; Francis Crick; James Watson; Fred Sanger; phages; genetics; mutation; Leslie Barnett; Alice Orgel; C. elegans; Muriel Wigby; nematode; John Sulston; Bob Horvitz; Director; genomics
Photographs:Author: Brackley, Paul
Title: Consortium including MRC Laboratory of Molecular Biology to provide Covid-19 protein reagents
Reference Cambridge Independent 21 May 2020
Year: 2020
Type: Science
Subject: The LMB is part of a consortium helping to provide vital reagents for free to enable Covid-19 research
Keywords: Covid-19; reagents; Protein Portal; SARS-CoV-2; Jan Löwe; CPPC; virus; antibodies
Photographs: Director Jan Löwe (Cambridge Independent Picture)Author: Quested, Tony
Title: New molecule to repair and restore brain and spinal cord function
Reference Business Weekly 1 September 2020
Year: 2020
Type: Science
Subject: A molecule created by a team of researchers lead by Radu Aricescu, can restore lost connections in the spinal cord and brain of mice with neurological disorders including cerebellar ataxia, Alzheimer’s disease and spinal cord injury.
Keywords: Radu Aricescu; cerebellin-1; ‘molecular bridge’; CPTX; spinal cord; brain; Alzheimer’s disease; epilepsy; cerebellar ataxia; neuronal cells
Photographs: Radu Aricescu in lab (MRC LMB)Author: Brackley, Paul
Title: Lost connections in the brains of mice with Alzheimer’s restored by MRC LMB in Cambridge
Reference Cambridge Independent 11 September 2020
Year: 2020
Type: Science
Subject: The astonishing work by scientists at the LMB and their international collaborators offers long-term hope of helping patients with a range of conditions including Alzheimer’s disease, spinal injury and epilepsy
Keywords: Radu Aricescu; spinal cord; brain; neurological disorders; Alzheimer’s disease; epilepsy; ‘molecular bridge’; repair; cerebellin-1; CPTX; Jonathan Elegheert; Amber Clayton; cerebellar ataxia; neuronal cells; synapses
Photographs: Radu Aricescu in lab (MRC LMB)Author: UKRI
Title: New molecule to repair and restore brain and spinal cord function
Reference UKRI News 28 August 2020
Year: 2020
Type: Science
Subject: A molecule created by researchers can restore lost connections in the spinal cord and brain of mice with neurological disorders including cerebellar ataxia, Alzheimer’s disease and spinal cord injury
Keywords: Radu Aricescu; spinal cord; brain; repair; Alzheimer’s disease; cerebellar ataxia; “molecular bridge”; cerebellin-1; epilepsy; synapses; CPTX
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