Author: Barr, Sabrina
Title: When you eat could be just as important as what what you eat for prevention of disease
Reference Independent 25 April 2019
Year: 2019
Type: Science
Subject: The time of day that you eat could be just as important to your wellbeing as the food you consume, a new study has found.
Keywords: circadian rhythm; “Period”; cardiovascular disease; type 2 diabetes; body clock; insulin; John O’Neill; food; wellbeing; meal timings; cellular clocks
Photographs:Author: Weeks, Mark
Title: Sir John Sulston (1942-2018)
Reference Wellcome News 9 March 2018
Year: 2018
Type: Obituary
Subject: The death of Sir John Sulston, and how he was an outstanding figure in UK biological and medical science and in Wellcome’s history.
Keywords: John Sulston; obituary; Wellcome Trust Sanger Institute; genome sequencing; Human Genome Project; nematode worm; C. elegans
Photographs:Author: Royal Society
Title: Sir Gregory Winter CBE FMedSci FRS Blockbuster drugs: from fantasy to reality
Reference Royal Society 29 November 2018
Year: 2018
Type: History - Reminiscences
Subject: An entire new class of drugs was launched as a result of technology developed by Sir Gregory Winter
Keywords: Gregory Winter; human antibodies; “humanise”; genetic engineering; Herceptin; Avastin; cancer; “pie-in-the-sky”; Cambridge Antibody Technology; Humira; AstraZeneca; Domantis; Bicycle Therapies; autoimmune diseases
Photographs: Sir Gregory informal shotAuthor: Cookson, Clive
Title: Stable research funding drives Britain’s ‘Nobel factory’
Reference The Financial Times 7 December 2018
Year: 2018
Type: Funding
Subject: How stable long-term funding contributes to the discoveries made by the LMB
Keywords: Greg Winter; Jan Löwe; “Nobel factory”; Richard Henderson; cryo-EM; funding model; Madeline Lancaster; cerebral organoids; mini brains; Alzheimer’s; autism; Greg Jefferis; Mick Hastings; circadian rhythms; molecular clocks; suprachiasmatic nucleus; antibody-based drugs; collaborative interaction
Photographs: Scientists in LMB lab; Jan Löwe in his office; Greg Winter outside Trinity College; inside the atrium of the buildingAuthor: Bates, Alex
Title: Size Matters: Mapping a Miniature Brain
Reference BlueSci Lent 2018
Year: 2018
Type: Science
Subject: Alex Bates discuses his PhD on mapping a small part of the fly brain
Keywords: Alex Bate; Juvenile fruit fly brain; QI; Alan Davis; Drosophila melanogaster; vinegar fly; ataxia; Alzheimer’s disease; Parkinson’s disease; electron microscopy; caenorhabditis elegans; ‘Tracey’; “Google maps’ of brains; neurons; mapping; penis brain; phallic;‘connectomic’
Photographs:Author: YaleNews
Title: Nobel laureate Thomas A. Steitz dies, mapped the structure of the ribosome
Reference YaleNews 10 October 2018
Year: 2018
Type: Alumni-Obituary
Subject: Thomas A. Steitz, Sterling Professor of Molecular Biophysics and Biochemistry at Yale and one of three winners of the 2009 Nobel Prize in Chemistry, died 9 October 2018
Keywords: Thomas A. Steitz; ribosome; antibiotics; Joan Steitz; obituary; X-ray crystallography
Photographs: Thomas A. Steitz portrait; Thomas at Nobel Prize ceremonyAuthor: Williamson, Lorna
Title: Richard Henderson’s Nobel Prize
Reference The Bulletin of the Royal College of Pathologists July 2018
Year: 2018
Type: Awards & Prizes
Subject: New developments in imaging individual molecules could unlock the structural basis of normal and abnormal biochemical pathways. rcpath, celebrate the work of Richard Henderson.
Keywords: Richard Henderson; cryo-EM; Nigel Unwin; bacteriorhodopsin; X-ray crystallography; atomic structures; Chris Tate; G pro- tein– coupled receptors (GPCRs); LifeArc; Heptares Therapeutics Ltd (HTL); rapid freezing
Photographs: Richard holding ball and spoke modelAuthor: Taylor, Mark
Title: Football is just a branch of science for Cambridge United Women midfielder Gisela Otten
Reference Cambridge Independent 7 December 2020
Year: 2020
Type: Miscellaneous
Subject: Gisela Otten, post-doctoral researcher in Felix Randow’s group in the LMB’s PNAC Division, talks to the Cambridge Independent about her route to joining Cambridge United WFC and combining this with her scientific career
Keywords: Gisela Otten; Cambridge United women’s team; midfield; football; bacterial infections; Church; Felix Randow
Photographs: Gisela playing foodball for United; Head shot of GiselaAuthor: Marshall, Michael
Title: How the first life on Earth survived its biggest threat-water (The water paradox and the origins of life)
Reference Nature 9 December 2020
Year: 2020
Type: Science
Subject: Living things depend on water, but it breaks down DNA and other key molecules. So how did the earliest cells deal with the water paradox?
Keywords: NASA; Perseverance; Jezero Crater; Lake; liquid water; John Sutherland; Mars; first biological cells; carbon based chemicals; wet and dry; Primordial soup; cyanamide; proteins; lipids; warm pond; Claudia Bonfio; prebiotic chemistry
Photographs:Author: Ferry, Georgina
Title: Women of the Nobel factory share their stories
Reference Nature 15 December 2020
Year: 2020
Type: Book Review
Subject: From sequencing to stardom — alumnae of the Laboratory of Molecular Biology reflect on how they succeeded in science for Kathleen Weston’s book
Keywords: Kathleen Weston; ‘sexist ads’; Ahead of the Curve; book review; “discrimination against mediocrity”; interviews; women; Elizabeth Blackburn; Sarah Teichmann; Joan Steitz; Fred Sanger; Max Perutz; Daniela Rhodes; Mariann Bienz; Hugh Pelham; Aaron Klug; Melina Schuh; ‘leaky pipline’; unconscious bias; impostor syndrome; salary disparities
Photographs:Author: British Neuroscience Association
Title: 2020 BNA Prize Winners!
Reference British Neuroscience Association 14 December 2020
Year: 2020
Type: Awards & Prizes
Subject: Alexander Bates wins the 2020 British Neuroscience Association Postgraduate Award
Keywords: Alexander Bates; award; Greg Jefferis; ‘connectomics’; British Neuroscience Association
Photographs: Alexander BatesAuthor: Parshley, Lois
Title: The many strange long-term symptoms of Covid-19, explained
Reference Vox 15 December 2020
Year: 2020
Type: Science
Subject: Article looking at the varied long-term effects of Covid-19 and the clues that latest research offers into what might be causing all the symptoms – including Madeline Lancaster lab’s study showing that SARS-CoV-2 can damage cells in the brain’s choroid plexus
Keywords: Covid-19; Long Covid; SARS-CoV-2; coronavirus; neurological symptoms; Madeline Lancaster; choroid plexus; postural orthostatic tachycardia syndrome (POTS); neuro-inflammation; cytokine storms; hyperinflammation; post-viral chronic fatigue syndome; deep vain thromboses; pulmonary problems
Photographs: Hospital picturesAuthor: Kiessling, Tilmann
Title: EMBO welcomes thirty Young Investigators
Reference EMBO 1 December 2020
Year: 2020
Type: Alumni - Awards & Prizes
Subject: LMB Alumnus Tanmay Bharat is among 30 life science researchers within their first four years as group leaders to become EMBO Young Investigators
Keywords: Tanmay Bharat; EMBO Young Invetigators; award; alumni
Photographs:Author: Cristo, Inês
Title: Cell scientist to watch - Hayley Sharpe
Reference Journal of Cell Science 8 December 2020
Year: 2020
Type: Alumni - Career Structure
Subject: Hayley Sharpe, a former PhD student with Sean Munro’s group in the Cell Biology Division, is interviewed by the Journal of Cell Science about her career so far, how she ended up studying phosphatases
Keywords: Hayley Sharpe; alumni; Sean Munro; Peter Lawrence; Babraham Institute; ultimate Frisbee; phosphatases; EMBO Young Investigator; Lister Institute Research Prize; career; lockdown
Photographs: Hayley Sharpe; Hayley with husband cyclingAuthor: Mogrify/MRC Laboratory of Molecular Biology
Title: Mogrify enters research collaboration with the MRC Laboratory of Molecular Biology
Reference Mogrify Press Release 11 January 2020
Year: 2020
Type: Science
Subject: Exploratory research project aims to develop novel protein expression systems via cell reprogramming
Keywords: Mogrify; ex vivo cell therapies; protein expression systems; LifeArc; Julian Gough; collaboration; project
Photographs:Author: Brackley, Paul
Title: Exploring why older women find it harder to fall pregnant
Reference Cambridge Independent 15-21 November 2017
Year: 2017
Type: Science
Subject: Melina Schuh established a new lab at Bourn Hall Clinic to uncover the biological secrets behind age and pregnancy
Keywords: Melina Schuh; Bourn Hall Clinic: older women; chromosomes; pregnant; meiosis; IVF; oocytes; Bianka Seres; spindle; kinetochores; miscarriage; fertility
Photographs: Melina Shuh, Bianka Seres in the new labAuthor: MRC Network
Title: How protein machinery drives healthy gene expression
Reference MRC Network Winter 2017/18
Year: 2017
Type: Science
Subject: Dr Lori Passmore and her team used cryo-electron microscopy (cryo-EM) – to study a large protein complex called ‘cleavage and polyadenylation factor’ or CPF.
Keywords: Lori Passmore; gene expression; ‘cleavage and polyadenylation factor’ (CPF); viral infections; atomic model; structure; machinery; cryo-EM
Photographs:Author: Booth, Robert
Title: Francis Crick Institute’s £700m building ‘too noisy to concentrate’
Reference The Guardian 21 November 2017
Year: 2017
Type: History - General
Subject: It is a £700m cathedral to biomedical science, where scientists work together to make breakthroughs in cancer, neuroscience, pandemics and genetics. But the Francis Crick Institute is not proving to be the easiest place to concentrate.
Keywords: The Francis Crick Institute; ‘too noisy to concentrate’; Alan Penn; “creative interplay”; building
Photographs: The Francis Crick Institute from outside: Inside view of Francis Crick InstituteAuthor: Brackley, Paul
Title: Royal Society award for Dr Greg Jefferis of MRC Laboratory of Molecular Biology as he seeks to understand how our brains work
Reference Cambridge Independent 19 July 2018
Year: 2018
Type: Awards & Prizes
Subject: Dr Greg Jefferis, group leader in the LMB’s Neurobiology Division, has been awarded the Francis Crick Medal and Lecture 2018
Keywords: Greg Jefferis; Francis Crick Medal; Drosophila; human brain; Royal Society; brain function; award; neurons
Photographs: Greg Jefferis in officeAuthor: Ward, Sally E., Jones, Peter, Buss, Tim, Rada, Cristina, Winter, Gregory, Willson, Richard
Title: In memoriam: Jefferson Foote
Reference MABS 12 January 2021
Year: 2021
Type: Alumni - Obituary
Subject: In a scientific career that spanned over three decades, Dr. Jeff Foote made seminal contributions to antibody humanization and the biophysical aspects of antibody recognition. In this Perspective, we discuss his life and work.
Keywords: Jefferson (Jeff) Foote; immunochemistry; antibody humanization; Greg Winter; Cesar Milstein; fluorometers; Macintosh (“Mac”); antibody engineering; CDR grafting; therapeutic; Campath-1; “conformational isomerism”; Perspective; Arrowsmith Technologies
Photographs: Jeff Foote with his Mac at the LMB.Author: Cookson, Clive
Title: ‘Mini-brains’ research brings neural development breakthrough
Reference Financial Times 24 March 2021
Year: 2021
Type: Science
Subject: Madeline Lancaster leads a team that have identified a key genetic switch that ensures humans develop much bigger brains than apes, an important step in the scientific understanding of neural development.
Keywords: Madeline Lancaster; mini-brains; cerebral organoids; apes; ZEB2; chimpanzee; neurons; human brain; radial glia; genetic switch; progenitor cells
Photographs: Human, left, and chimpanzee mini-brains at five weeks oldAuthor: Sample, Ian
Title: Scientists discover why the human brain is so big
Reference The Guardian 24 March 2021
Year: 2021
Type: Science
Subject: Madeline Lancaster’s group have shed light on the why humans develop much bigger brains than apes, an important step in the scientific understanding of neural development.
Keywords: Madeline Lancaster; large brains; “brain organoids”; apes; ZEB2; human; chimp; progenitor cells; neural; switch
Photographs:Author: Blakely, Rhys
Title: Lab grows small brains to answer the big question
Reference The Times 25 March 2021
Year: 2021
Type: Science
Subject: Madeline Lancaster’s group have shed light on the why humans develop much bigger brains than apes, an important step in the scientific understanding of neural development.
Keywords: Madeline Lancaster; “mini-brains”; human; chimpanzee; stem cell; ZEB2; organoids; neurons; progenitor cells; apes
Photographs: Madeline with her group; image of human organoidAuthor: Brackley, Paul
Title: Winners of Cambridge Independent Science and Technology Awards revealed
Reference Cambridge Independent 23 April 2021
Year: 2021
Type: Awards & Prizes
Subject: The LMB has received a Special Commendation in the category of Covid-19 Response Award, in the Cambridge Independent Science and Technology Awards
Keywords: Cambridge Independent Science and Technology Awards; Covid-19 Respose Award; special commendation; Zunlong Ke; John Briggs
Photographs:Author: Shahbazi, Marta N.
Title: Defining myself as a mother scientist
Reference Cell Stem Cell 6 May 2021
Year: 2021
Type: Career Structure
Subject: As part of a series covering how researchers have been impacted by the COVID-19 pandemic, Science Direct have featured Marta Shahbazi and her experience of juggling being a new group leader and a new mother during lockdown.
Keywords: Marta Shahbazi; COVID-19; mother; coronavirus pandemic; double life; Group Leader
Photographs: Marta in the lab (MRC LMB)