Author: Lawrence, Peter
Title: Celia Milstein obituary
Reference The Guardian 16 December 2020
Year: 2020
Type: Obituary
Subject: Peter Lawrence recalls his friend Celia Milstein who has died at the age of 92.
Keywords: Celia Milstein; obituary; César Milstein; monoclonal antibodies; Babraham research campus
Photographs: Celia in her garden; Celia visiting the biochemisty department in 1958Author: Clare Hall
Title: “Being part of Clare Hall was, and still is, an altogether enriching experience”
Reference Clare Hall, University of Cambridge 10 January 2022
Year: 2022
Type: Career Structure
Subject: Wasi Faruqi reflects on his scientific career and his engagement with Clare Hall as a Life Member.
Keywords: Wasi Faruqi; MBE; career; Clare Hall; Murray Stewart; X-ray; Electron Microscopy; Hugh Huxley; cryo-EM; Richard Henderson
Photographs: Wasi in his office (MRC-LMB photo)Author: Trinity College Cambridge
Title: Didier Queloz and John Sutherland lead £10m Leverhulme Centre for Life in the Universe
Reference Trinity College Cambridge 13 January 2022
Year: 2022
Type: Science
Subject: The Leverhulme Centre for Life in the Universe to support international and cross-disciplinary research on planetology and life beyond Earth is being established with, John Sutherland, being appointed as Associate Director of the centre
Keywords: John Sutherland; Didier Queloz; The Leverhulme Centre for Life in the Universe; University of Cambridge; chemistry of life; Mars; Planetary Science and Life in the Universe (IPLU); prebiotic; Astrophysics; interdisciplinary
Photographs: Image of Professor Didier Queloz and Professor John SutherlandAuthor: ALZFORUM
Title: Cryo-EM Unveils Distinct Aß42 Fibril Structures for Sporadic, Familial AD
Reference ALZFORUM 14 January 2022
Year: 2022
Type: Science
Subject: A recent structural study led by Sjors Scheres, Michel Goedert and Benjamin Ryskeldi-Falcon’s groups has used cryo-EM to detect two main types of Aβ42 filaments from both sporadic and familial Alzheimer’s disease
Keywords: Cryo-EM; Aß42; Sjors Scheres; Ben Ryskeldi-Falcon; Michel Goedert; S Shapes; Fibrils; filaments; tauopathies; luminescent conjugated oligothiophenes (LCOs); neurodegenerative diseases; Tau
Photographs:Author: Cambridge Biomedical Campus
Title: Cambridge demonstrates how science is improving lives
Reference Cambridge Biomedical Campus 25 January 2022
Year: 2022
Type: Miscellaneous
Subject: The LMB recently welcomed George Freeman MP as part of a wider visit to the Cambridge Biomedical Campus to learn how Cambridge is leading innovation in life sciences
Keywords: Cambridge Biomedical Campus (CBC); George Freeman MP; life science; Jan Löwe; Madeline Lancaster; Chris Russo; visit
Photographs:Author: Stoddart, Charlotte
Title: Structural biology: How proteins got their close-up
Reference Knowable Magazine 3 January 2022
Year: 2022
Type: History - General
Subject: Richard Henderson, from the Structural Studies Division, discusses his work and the evolution of structural biology on the Knowable podcast
Keywords: William Bragg; Lawrence Bragg; X-ray crystallography; James Watson; Francis Crick; Maurice Wilkins; John Kendrew; Myoglobin; Max Perutz; heavy atoms; Richard Henderson; protein structure; EDSAC; ‘computer girls’; Dorothy hodgkin; Rosalind Franklin; amino acids; Roger Kornberg; Cryo-EM; synthetic biology; genetic code
Photographs:Author: O’Toole, Peter
Title: Brad Amos (MRC Laboratory of Molecular Biology)
Reference The Microscopists 11 March 2022
Year: 2022
Type: Career Structure
Subject: Emeritus scientist Brad Amos is a guest on The Microscopists podcast from Bitesize Bio
Keywords: Brad Amos; Linda Amos; Gail McConnell; Mesolens; confocal microscope; zoology; John White; Mike Fordham; Bio-Rad; monoclonal antibody; John Gilmartin; skits; Robin Hood; the Full Monty; César Milstein; postage stamp; Ascension island
Photographs:Author: Newman, Andy; Luisi Ben
Title: Kiyoshi Nagai. 25 June 1949-27 September 2019
Reference Biographical Memoirs of Fellows of The Royal Society 16 March 2022
Year: 2022
Type: Alumni - Obituary
Subject: Royal Society Biographical Memoir, written by Andy Newman and Ben Luisi looks at the life and career of Kiyoshi Nagai who died in September 2019
Keywords: Kiyoshi Nagai; haemoglobin; spliceosome; Max Perutz; John Kilmartin; Hans Thøgersen; John Kendrick-Jones; Chris Oubridge; Aaron Klug; Daniela Rhodes; Giulio Fermi
Photographs: Kiyoshi as a young man; Kiyoshi in lab with Chris Oubridge; Kiyoshi with Richard Henderson and Venki RamakrishnanAuthor: Cambridge Independent
Title: TB research pioneer joins LMB division
Reference Cambridge Independent February 23-March 1 2022
Year: 2022
Type: Career Structure
Subject: Lalita Ramakrishnan joins the LMB Cell Biology Division as a group leader
Keywords: Lalita Ramakrishnan; TB; Cambridge Molecular Immunity Unit; zebrafish; Mycobacterium marinum; group leader
Photographs: Lalita in the lab (MRC LMB photo)Author: Brackley, Paul
Title: LMB solves structure of ALS molecule to aid hunt for drugs
Reference Cambridge Independent 23 December 2021
Year: 2021
Type: Science
Subject: The structure of the molecule associated with ALS has been determined for the first time by Ben Ryskeldi-Falcon’s Group
Keywords: Amyotrophic lateral sclerosis (ALS); Motor neurone disease; Clumped TDP-43; Alzheimer’s disease; Parkinson’s; Benjamin Ryskeldi-Falcon; Diana Arseni; Alexey Murzin; cryo-EM; amyloid filaments; tau; alpha-synuclein; FTD; neurodegenerative disease; ‘aggregates’
Photographs: Image of Ben; Image of Clumped TDP-43 (MRC-LMB)Author: Cambridge Network
Title: First detailed images captured of molecule associated with ALS
Reference Cambridge Network 10 December 2021
Year: 2021
Type: Science
Subject: The structure of the molecule associated with ALS has been determined for the first time by Ben Ryskeldi-Falcon’s Group
Keywords: Amyotrophic lateral sclerosis (ALS); TDP-43; cryo-EM; Benjamin Ryskeldi-Falcon; neurodegenerative disease; clumping; aggregates
Photographs:Author: LifeArc
Title: LifeArc’s technology transfer team supports MRC researchers in making cryo-electron microscopy even sharper
Reference LifeArc 3 November 2021
Year: 2021
Type: Science
Subject: LifeArc filed applications for a patent and trademark for the new all-gold grids developed by Chris Russo’s group. Helping to bring them to the marked as soon as possible.
Keywords: cryo-EM; gold grids; HexAuFoil; Chris Russo; LifeArc; ‘cryoEvap’; gold film
Photographs: Picture of gold grid (MRC LMB)Author: Blakely, Rhys
Title: Man-made cell that produces plastics and medicines hailed as revolutionary in biology
Reference The Times 4 June 2021
Year: 2021
Type: Science
Subject: Jason Chin’s group have created a new type of cell capable of producing substances such as plastics and medicines in a way not seen in the natural world
Keywords: Jason Chin; biodegradable plastics; antibiotics; synthetic chemistry; polymers; codons; tRNA; monomers; polymers; genome; genetic code; amino acid; bacteria
Photographs:Author: Brackley, Paul
Title: Discovery over receptors could change our understanding of molecular neuroscience
Reference Cambridge Independent 8 April 2022
Year: 2022
Type: Science
Subject: A recent paper from Radu Aricescu’s group was a structural investigation into type A gamma-aminobutyric acid receptors has found that their subunit arrangements are far more varied than previously thought
Keywords: Radu Aricescu; GABAA receptors; type A gamma-aminobutyric acid receptors; Andrija Sente; Jonas Miehling; Tomas Malinauskas; Wellcome Centre for Human Genetics; cryo-EM; Katerina Naydenova; computational strategy; signalling; drug targets; central nervous system; inhibitory neurotransmission; ‘action potential’; neuron
Photographs: Scientific image of GABAA receptors (MRC LMB)Author: ALZFORUM
Title: Suprise! TMEM106b Fibrils Found in Neurodegenerative Disease
Reference ALZFORUM 12 April 2022
Year: 2022
Type: Science
Subject: Alzforum summarises three recent papers which analysed TMEM106b amyloid filaments in the human brain – including research from Sjors Scheres’ and Michel Goedert’s groups in the LMB’s Structural Studies and Neurobiology Divisions respectively
Keywords: David Eisenberg; TDP-43; TMEM106b fibris; Michel Goedert; Sjors Scheres; neurodegenerative disease; FTLD-TDP; cryo-EM; “fuzzy coat”; Benjamin Ryskeldi-Falcon; C-terminal fragment; ultracentrifugation; TMEM239; antibody
Photographs:Author: bicycle therapeutics Press Release
Title: Bicycle Therapeutics announces updated preclinical data on SARS-CoV-2 antivirals at the 2022 microbiology society annual meeting
Reference bicycle therapeutics 7 April 2022
Year: 2022
Type: Science
Subject: Bicycle Therapeutics reports on its updated preclinical data produced in collaboration with Leo James’ group. In vitro tests of their proprietary bicyclic peptide show promise for antiviral modality against SARS-CoV-2
Keywords: Bicycle Therapeutics; biotechnology; SARS-CoV-2; Microbiology Society Annual Meeting; Leo James; preclinical data; anti-viral; bicycle Toxin Conjugate
Photographs:Author: DZNE
Title: “Hartwig Piepenbrock-DZNE Prize” Honors Research on Brain Diseases
Reference DZNE 16 May 2022
Year: 2022
Type: Awards & Prizes
Subject: To mark the award of the Hartwig Piepenbrock-DZNE Prize for his ground-breaking research into the molecular basis of neurodegenerative diseases, DZNE have released a video portrait of Michel Goedert
Keywords: Michel Goedert; neurodegenerative disease; Hartwig Piepenbrock-DZNE Prize; Alzheimer’s; Parkinson’s; Hartwig Piepenbrock-DZNE; tau; alpha-synuclein protein
Photographs: Michel receiving the prizeAuthor: Nature
Title: Hot headed: brain temperature can exceed 40 degrees
Reference Nature 23 June 2022, p.627
Year: 2022
Type: Science
Subject: Magnetic resonance spectroscopy allowed Nina Rzechorzek (member of the O’Neill group, Cell Biology) and collaborators to create a HEATWAVE map
Keywords: Temperature; brain; Nina Rzechorzek; John O’Neill; scans; 40ºC; traumatic brain injury; rises and falls
Photographs: Image showing the different temperature of male and female brains. (MRC-LMB)Author: Biochemical Society
Title: 2023 Award Winners Biochemical Society
Reference Biochemical Society 7 April 2022
Year: 2022
Type: Alumni - Awards & Prizes
Subject: Stephen Wallace has been awarded The Colworth Medal, given by The Biochemical Society to recognise outstanding research by a biochemist within 10 years of PhD completion
Keywords: Biochemical Society’s Awards 2023; Stephen Wallace; Colworth Medal; Jason Chin; alumni
Photographs:Author: Laurans, Penelope
Title: Sidney Altman, pathbreaking scientist
Reference YaleNews 6 April 2022
Year: 2022
Type: Alumni - Obituary
Subject: Sidney Altman was a ground-breaking scientist in the field of RNA biology, whose discovery of catalytic properties of RNA led to the award of the Nobel Prize in Chemistry in 1989
Keywords: Sidney Altman; catalytic properties; RNA; Sydney Brenner; Francis Crick; Yale; alumni
Photographs: Image of Sidney AltmanAuthor: Snyder, Bill
Title: Lehmann named to receive Vanderbilt Prize in Biomedical Science
Reference Vanderbilt University Medical Centre 20 April 2022
Year: 2022
Type: Alumni - Awards & Prizes
Subject: Ruth Lehmann is the 2022 recipient of the Vanderbilt Prize in Biomedical Science, and she was a Postdoctoral Visitor with Michael Wilcox and Peter Lawrence in the Cell Biology Division.
Keywords: Ruth Lehmann; Director Whitehead Institute for Biomedical Research; alumni; Cell Biology; Vanderbilt Prize in Biomedical Sciences; fruit fly Drosophila; germ cells
Photographs: Image of Ruth LehmannAuthor: Ananthasubramaniam, Bharath
Title: Introducing the next SRBR Public Outreach Fellow
Reference Society for Research on Biological Rhythms 30 June 2022
Year: 2022
Type: Career Structure
Subject: Andrew Beale, a postdoc in John O’Neill’s group in the Cell Biology Division, discusses his plans as new Public Outreach Fellow for the Society for Research on Biological Rhythms (SRBR),
Keywords: Andrew Beale; John O’Neill; SRBR Public Outreach Fellow; biological rhythms; Circadian rhythms; public engagement; chronobiology; temperature sensitivity; Clockbites
Photographs: Head shot of Andrew BealeAuthor: Stemm, Holly
Title: Student to success story: Our Undergraduate Research Opportunity Program
Reference CSIROscope 18 July 2022
Year: 2022
Type: Career Structure
Subject: Ben Porebski, an Investigator Scientist in Philipp Holliger’s group in PNAC Division, discusses his career so far
Keywords: Ben Porebski; Undergraduate Research Opportunity Program (UROP); real-world experience; biomedical; Computer sciences; wet lab; CSIRO; Australia; “mixed placement’
Photographs: Ben Porebski in the lab (MRC-LMB)Author: Malins, Abi
Title: Inja Radman
Reference WATT 11 August 2022
Year: 2022
Type: Alumni- Career Structure
Subject: Inja Radman discusses her career so far with Women Ahead of Their Time (WATT), including the “fantastic time” she spent as a PhD student and Investigator Scientist in Jason Chin’s group
Keywords: Inja Radman; biotech; Silicon Valley; genetics; Summer School of Science; Jason Chin; Synthetic Biology; WATT; IndieBio; New Culture; Matt Gibson; cellular agriculture;
Photographs: Head shot of Inja RadmanAuthor: Kilmartin J. V., Crowther R. A.
Title: Vernon Martin Ingram - Biographical Memoirs
Reference Royal Society Memoirs 10 August 2022
Year: 2022
Type: Alumni - Obituary
Subject: Vernon Ingram Royal Society Biographical Memoir, written by emeritus scientists John Kilmartin and Tony Crowther.
Keywords: Vernon Ingram; X-ray crystallography; sickle cell haemoglobin; neurodegenerative disease; heavy atom; Max Perutz; Cavendish Laboratory; John Kendrew; Francis Crick; thalassaemia; erythroleukaemia cells; HeLa; Alzheimer’s disease; Huntington’s disease
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