Author: Hegarty, Stephanie
Title: Is a cure for the common cold on the way?
Reference BBC News 20 December 2011
Year: 2011
Type: Science
Subject: Look at whether recent research could eventually mean that colds are a thing of the past.
Keywords: Antiviral; Todd Rider; Massachusetts Institute of Technology (MIT); Draco; H1N1; swine flu; polio virus; cold; dengue fever; Ebola virus; Vaccinations; Dr Leo James; Professor Peter Palese; Mount Sinai Medical School; Dr Benhur Lee; Hugh Pennington; Interferons
Photographs:Author: Howes, Laura
Title: Cutting edge chemistry in 2011
Reference RSC 20 December 2011
Year: 2011
Type: Science
Subject: Discoveries that have caused the biggest buzz in Chemistry labs in 2011. A panel of journal editors reviews this years chemical science papers that include Phil Holliger.
Keywords: Philipp Holliger; Francis Crick; RNAzyme; RNA; self-replicating
Photographs:Author: Blow, Nathan
Title: Evolution at the Lab Bench
Reference Biotechniques 2 February 2012
Year: 2012
Type: Science
Subject: Overcoming the PCR inhibitors often present in complex environmental samples. A look at the many ways directed evolution is enhancing protein function.
Keywords: Philipp Holliger; polymerases; Svante Paabo; Max Planck Institute; compartmentalized self-replication (CSR); molecular breeding; 2D9; David Liu; PACE; phage M13; PIII; Taq polymerase; environmental inhibitors; Jerry Joyce
Photographs: Picture of David Liu: image of 2D9; diagram of the PACE systemAuthor: GEN News Highlights
Title: Investigators Describe Bioorthogonal Reaction for Rapid Site-Specific Protein Labeling
Reference GEN 6 February 2012
Year: 2012
Type: Science
Subject: LMB Scientist and colleagues at the North Carolina State University have created specially engineered mammalian cells to enable researchers to label proteins of interest more efficiently
Keywords: North Carolina State University (NCSU); norbornene; Jason Chin; bioorthogonal; tetrazines; aminoacyl-tRNA; synthetase/tRNA; Methanosarcina; PylRS/tRNACUA; L-lysine
Photographs:Author: Cambridge News
Title: Scientist is knighted
Reference Cambridge News 10 February 2012
Year: 2012
Type: Awards & Prizes
Subject: Hugh Pelham receives knighthood at Buckingham Palace
Keywords: Hugh Pelham; Queen’s Birthday Honours; Director; knighthood; Prince of Wales
Photographs: Hugh Pelham being knighted by the Prince of Wales.Author: The Royal Society
Title: How new science is transforming the optical microscope
Reference The Royal Society 13 February 2012
Year: 2012
Type: Talks/Lectures
Subject: The 2012 Leeuwenhoek Lecture was given by Brad Amos.
Keywords: Leeuwenhoek Lecture; Brad Amos; optical microscope; John White; University of Strathclyde; biological laser-scannning confocal microscope; lens size; ‘small lens’; fluorescent probes
Photographs: Flea, MRC pictureAuthor: Quested, Tony
Title: Cambridge Technology Cluster Thriving Thanks to University Dynamism
Reference Business Weekly 24 February 2012
Year: 2012
Type: Biotechology Companies
Subject: How the Cambridge technology cluster and its evolution link back to the University of Cambridge
Keywords: “All Roads lead to Rome’; Cambridge technology cluster; Genentech; Sir Chris Evans; Alan Goodman; Andy Richards; Shai Vyakarnam; Yupar Mint; Cambridge University; Judge Business School; TTP, Generics (Sagentia); Plextek; 42T; Hermann Hauser; Andy Hopper; Chris Lowe; Greg Winter; Richard Friend: David Cleevely; Cambridge Antibody Technology (CAT); HUMIRA; D2E7; Abbott Laboratories; TNF alpha; AstraZeneca; Bicycle Therapeutics; biotherapeutics; Dr Christian Heinis; Domantis; King Faisal Internation Prize for Medicine; Cancer Research Institute William B. Coley Award
Photographs: Sir Greg WinterAuthor: News Medical
Title: Study identifies new processes that lead to development of novel cell implicated in allergies
Reference News Medical 28 February 2012
Year: 2012
Type: Science
Subject: The discovery of new cell that has potential for targeted treatment of asthma
Keywords: Trinity College Dublin; asthma; Professor Padraic Fallon; Andrew McKenzie; atopic dermatitis; nuocyte;RORalpha; allergic inflammation
Photographs:Author: Zivkovic, Bora
Title: A Blog Around The Clock, Rhythms of Life in Meatspace and Cyberland
Reference Scientific American 21 March 2012
Year: 2012
Type: Miscellaneous
Subject: Interview with Josh Witten
Keywords: Josh Witten; Mike White; Washington University; The Finch & Pea; ‘Song of the Week’; Marie-Claire Shanahan; evolutionary theory; natural selection; Theodosius Dobzhansky; SciencOnline2012
Photographs: Image of Josh WittenAuthor: MRC
Title: £49m to study the human brain at the molecular level
Reference MRC News 26 March 2012
Year: 2012
Type: Funding
Subject: LMB awarded £49m to examine the biology of the brain at a molecular level.
Keywords: Dementia; Parkinson’s; multiple sclerosis; cellular neurobiology; neurodegenerative diseases; synaptic activity; Titan Krios electron microscope; Centre for Chemical and Synthetic Biology; cellular damage; Jason Chin; Sir Hugh Pelham
Photographs:Author: Karuso, Peter
Title: The chemical basis for life, The 2009 Nobel Prize in Chemistry, Part 1
Reference Chemistry in Australia December 2009
Year: 2009
Type: Awards & Prizes
Subject: Story of the 2009 Nobel Prize in Chemistry for the structure and mechanistic interpretation of ribsomes
Keywords: Venki Ramakrishnan; Thomas A. Steitz; Ada Yonath; RNA; ribosome; Rib-X; antibiotics; ~54 proteins; Weizmann Institute; extremophiles; Heinz Gunter Wittmann; Sir John Kendrew; Bacillus 50S subunit; atomic resolution; Hakon Hope; Harry Noller; Peter Moore; NMR spectroscopy
Photographs: Coloured transmission electron micrograph of ribsomes Ada YonathAuthor: Karuso, Peter
Title: The chemical basis for life: The 2009 Nobel Prize in Chemistry. Part 2
Reference Chemistry in Australia February 2010
Year: 2010
Type: Awards & Prizes
Subject: Second instalment of the Story of the 2009 Nobel Prize in Chemistry for the structure and mechanistic interpretation of ribsomes
Keywords: Venki Ramakrishnan; Tom Steitz; Peter Moore; Harry Noller; and Ada Yonath; 30S subunit; ribosome; atomic resolution; Rib-X; RNA; Yale University; Cryo-EM; Heinz Gunter Wittmann; NMR spectroscopy; 50S subunit; Marin van Heel
Photographs: Venki Ramakrishnan (LMB Picture); Tom SteitzAuthor: Townsend, Angela
Title: CWRU researcher Jonathan Karn seeks way to find HIV when it is hiding
Reference Cleveland. com 17 April 2012
Year: 2012
Type: Science
Subject: Former LMB scientist Jonathan Karn received an grant awarded from amfAR to continue his research on HIV latency.
Keywords: American Foundation for AIDS Research (amfAR); Rowena Johnston; Case Western Reserve University School of Medicine (CWRU); Jonathan Karn; HIV; “what ‘s keeping the lid on the pot”; California Institute of Technology; Massacshusetts General Hospital; Ghent University Hospital; HIV/AIDS; Dr. Nathan Berger; Dr. David Margolis; Collaboratory of AIDS Researchers for Eradication (CARE)
Photographs: Jonathan KarnAuthor: Discover Magazine
Title: Synthetic XNA molecules can evolve and store genetic information, just like DNA
Reference Discover Magazine 20 April 2012
Year: 2012
Type: Science
Subject: Phil Holliger's group has developed six alternative polymers called XNAs that can also store genetic information and evolve through natural selection
Keywords: Vitor Pinheiro; XNA; natural selection; synthetic genetics; Phil Holliger; synthetic nucleic acids; polymerases; aptamers; HNA; CeNA, FANA; TNA; LNA; ANA; Alex Taylor; Steve Benner; Gerald Joyce
Photographs: Figure showing the six alternative polymers called XNAs.Author: BBC News
Title: Evolution seen in ‘synthetic DNA’
Reference BBC News 19 April 2012
Year: 2012
Type: Science
Subject: Researchers have succeeded in mimicking the chemistry of life in synthetic versions of DNA and RNA molecules.
Keywords: synthetic biology; Philipp Holliger; Goldilocks; XNAs; polymerase; Gerald Joyce; synthetic genetics; nucleobases; polymers
Photographs:Author: BBC News
Title: Addenbrooke’s celebrates opening by the Queen 50 years ago
Reference BBC News 28 May 2012
Year: 2012
Type: History - Reminiscences
Subject: Addenbrooke’s celebrates its 50th anniversary since it was officially opened by the Queen in 1962.
Keywords: Addenbrooke’s; anniversary; the Queen; Dr Mary Archer; Michael Fuller; ball and spoke model; pipe cleaners; party; Trumpington Street
Photographs: Queen speaking to a patient in 1962.Author: ScienceDaily
Title: Halogen Bonding Helps Design New Drugs
Reference ScienceDaily 5 June 2012
Year: 2012
Type: Science
Subject: Scientists have demonstrated that halogen bonding can be used to identify potential drug candidates for drug treatment.
Keywords: Halogen; chlorine; bromine; iodine; Dr. Rainer Wilcken; Prof. Frank Bockler; Dr. Andreas Joerger; Prof. Sir Alan Fersht; University of Tubingen; halogen bonding; HEFLibs
Photographs:Author: Business Wire
Title: Enamine, MRC LMB and IOCB Announce Collaboration to identify Novel Rhomboid Protease Inhibitors for Treatment of Various Diseases.
Reference Business Wire 6 June 2012
Year: 2012
Type: Science
Subject: Collaboration agreement signed between Enamine Ltd, LMB and IOCB to discover potential drug treatments
Keywords: Enamine Ltd; Institute of Organic Chemistry and Biochemistry of the Academy of Science of the Czech Republic (IOCB); Rhomboid Protease; Dr. Sergey Zozulya; Dr. Matthew Freeman; Dr. Kvido Strisovsky; Molecular Modelling; Compound Library; Screening Assays; Hit Finding and Characterization; Hit to Lead Chemistry; ADMET; collaboration agreement
Photographs:Author: Holding, Andy
Title: The LMB at 50
Reference MRC insights 12 June 2012
Year: 2012
Type: Events/Celebrations
Subject: Andy Holding who is a researcher at LMB writes about what it is like to work at such an historic institution as it prepares to move to a new home.
Keywords: The Eagle; Addenbrooke’s; Watson; Crick; 50 years; the Queen; Sean Munro; Venki Ramakrishnan; Max Perutz
Photographs: Michael Neuberger cutting the 50th birthday cake.Author: PR Newswire
Title: Heptares and UK Medical Research Council Extend GPCR Collaboration.
Reference PR Newswire 19 June 2012
Year: 2012
Type: Science
Subject: Heptare Therapeutics has extended its collaboration with the MRC.
Keywords: Heptares Therapeutics; G- protein coupled receptors (GPCR); National Institute of Medical Research (NIMR); Chris Tate; Dave Tapolczay; Malcolm Weir
Photographs:Author: ALN Magazine
Title: Mapping the Neural Network Governing Male Roundworm Mating.
Reference ALN Magazine 31 July 2012
Year: 2012
Type: Science
Subject: Researchers have determined the complete wiring diagram for the part of the nervous system controlling mating in male roundworm Caenorhabditis elegans.
Keywords: Caenorhabditis elegans; Albert Einstein College of Medicine of Yeshiva University; synapses; Scott Emmons; Travis Jarrell; Yi Wang; Adam Bloniaz; Christopher Brittin; Meng Xu; David Hall; J. Nichol Thomson; Donna Albertson; nervous system; connectomics; “connectome”
Photographs:Author: Geddes, Linda
Title: Synthetic ‘upgrade’ for fruit fly’s DNA
Reference New Scientist 13 August 2012
Year: 2012
Type: Science
Subject: Genetic code of the fruit fly Drosophila has been hacked into allowing it to make proteins with properties that don’t exist in the natural world.
Keywords: Drosophila; Jason Chin; amino acids; Paul Freemont; Centre for Synthetic Biology and Innovation; enzymes; codons; fruit fly
Photographs: Image of fruit fly Drosophila.Author: Cambridge News
Title: Students embrace the art of science
Reference Cambridge News 24 August 2012
Year: 2012
Type: Exhibitions
Subject: Young artists from across Cambridgeshire have combined science with art for an annual creative challenge, Imagining the Brain.
Keywords: Imagining the Brain; Different Ways of Thinking; Luke Woodhouse; Cambridge Regional College (CRC); The Complex Dynamic of Thought; artist in residence; Chelsey Bishop; The Leys School; autism; Charlotte Donald; Netherhall Sixth Form College; Emma Horsfall; Eildh Maccullum; Yvonne Vallis; Rosie O’Donovan; Kettle’s Yard; Karen Thomas; 2012 KPMG Schools Award for Science Communication
Photographs: Image of the winners.Author: Allen, Rachel
Title: Scientists reveal DNA danger from drinking alcohol
Reference Cambridge News 30 August 2012
Year: 2012
Type: Science
Subject: Cambridge Scientists reveal that drinking alcohol can cause irreversible damage to DNA leading to deadly conditions.
Keywords: bone marrow failure; Fanconi’s Anaemia (FA); KJ Patel; “Asian flush syndrome’; enzyme; toxic acetaldehyde; leukaemias; alcohol
Photographs:Author: Eades, Jude
Title: Celebrating 100 years
Reference Medical Research Council - Insight 18 September 2012
Year: 2012
Type: Events and Celebrations
Subject: A look at the 100th birthday celebrations and events taking place to mark the occasion as well as the future with the new laboratory opening 2013.
Keywords: 100th Birthday; Science Museum; Imperial Collage London; Sir Melvyn Bragg; Lord Robert Winston; MRC centenary installation; MRC Clinical Sciences Centre; The great British sleep survey; the great worm hunt; Galaxy Zoo; Hubble telescope; nematode worms; a century of amplified music; new building; MRC Achievements Timeline
Photographs: Image of new building (LMB) Children at a science event