Author: MRC News
Title: Redirecting the rules of attraction in fruit flies
Reference MRC News 19 December 2013
Year: 2013
Type: Science
Subject: Greg Jefferis group have discovered a biological switch that determines which part of the fruit fly’s brain responds to pheromones, depending on whether it is male or female.
Keywords: Fruit fly; pheromones; Greg Jefferis; cVA; ‘fruitless’ gene; Hugh Perry; biological switch; brain wiring
Photographs:Author: MBS, Modern Building Services
Title: The Medical Research Council Laboratory of Molecular Biology
Reference MBS 6 February 2014
Year: 2014
Type: Architecture and Buildings
Subject: Further details of how the LMB’s new building is kept running to meet the needs of the LMB’s scientific community
Keywords: new building; Cambridge Biomedical Campus; £212 million; paired chromosomes; interstitial service voids; Matt Nockolds; Stephen Holmes; HVAC system; 2400 VAV units; electricity meters; rotary heat exchangers; chillers; fan-coil units; boilers; ‘intelligent building’; atrium
Photographs: Matt Nockolds and Stephen Holmes, Outside of new building; atriumAuthor: University of Cambridge
Title: The LMB: past, present and future....
Reference University of Cambridge 17 February 2014
Year: 2014
Type: Historical - LMB History
Subject: The University has now taken over the old Laboratory of Molecular Biology (LMB) buildings from the MRC
Keywords: ‘Block 7’; Clifford Allbutt Building; ‘Unit for Research on the Molecular Structure of Biological Systems’; Cavendish Laboratory; Department of Physics; Max Perutz; John Kendrew; Jim Watson; Francis Crick; Venti Ramakrishnan; Clinical School; Richard Henderson; Paul Luzio
Photographs: Original LMB building; Richard Hederson and Paul Luzio with the renamed old LMB Building.Author: Luke, Adam
Title: Mental health training programme earns national recognition for two Cambridgeshire organisations
Reference Cambridge News 25 February 2014
Year: 2014
Type: Awards & Prizes
Subject: A training project to raise awareness of mental health issues at work has earned national recognition for Mind in Cambridgeshire and the MRC
Keywords: Mental Health First Aid (MHFA); ‘wellbeing champions’; Mel Nunn; Amie Blake; Alison Turnock; Mind in Cambridgeshire; award
Photographs: Amie Blake; Alison Turnock; Mel Nunn and Mel Nunn out the front of the LMB buildingAuthor: Jaques, Helen
Title: Comprehending Protein Complexes
Reference AcademiaNet 19 March 2014
Year: 2014
Type: Science
Subject: Interview with Lori Passmore discussing her work on complex multi-protein structures.
Keywords: Lori Passmore; enzymatic mechanisms; yeast; eukyaryotes; Fanconi anaemia; leukaemia; bone marrow; Poly(A); “cleavage and polyadenylation factor” (CPF); Ccr4-Not; cryo-EM: David Barford; Venki Ramakrishnan
Photographs: Lori Passmore in lab (MRC picture)Author: University of Oxford
Title: Matthew Freeman to be awarded Novartis Medal and Prize
Reference Sir William Dunn School of Pathology 2 April 2014
Year: 2014
Type: Awards & Prizes
Subject: Matthew Freeman, former Head of Cell Biology, now Head of Sir William Dunn School of Pathology in Oxford, is to receive the Novartis Medal and Prize from the Biochemical Society in 2015
Keywords: Matthew Freeman; Novartis Medal and Prize; Biochemical Society conference; regulated proteolysis; membrane trafficking; signal transduction; developmental cell biology
Photographs:Author: Sedwick, Caitlin
Title: Melina Schuh: First comes the egg
Reference Journal of Cell Biology 31 March 2014
Year: 2014
Type: Science
Subject: Melina Schuh from Cell Biology division discusses her work on oocytes in an interview for the Journal of Cell Biology
Keywords: Melina Schuh; oocyte meiotic spindle; epithelial cell; mitotic; centrosomes; asymmetrc; cytoplasic actin network; microtubules; Myosin-Vb; egg
Photographs: Melina Schuh (LMB Image)Author: Havergal, Chris
Title: George Osborne backs Papworth Hospital’s move to Cambridge as he announces £200m polar research ship for city’s British Antarctic Survey
Reference Cambridge News 25 April 2014
Year: 2014
Type: Funding
Subject: The Chancellor George Osborne visited the LMB on 25th April to announce that the science budget would continue to back research in Cambridge
Keywords: George Osborne; The Cancellor: Papworth Hospital; research “clusters”; British Antartic Survey; announcement
Photographs: George OsborneAuthor: Nightingale, Katherine
Title: Max Perutz: science communicator
Reference MRC insight 12 May 2014
Year: 2014
Type: Historical - LMB History
Subject: A look back at the Max Perutz Science Writing Award created in honour Max and his long-held interest in words
Keywords: Max Perutz; quotations; New Scientist; “scientist as poet’; tea: coffee breaks; Royal Institution; Christmas lectures; PhD Students; haemoglobin; Lewis Thomas Prize
Photographs:Author: Ledwith, Sara
Title: AstraZeneca arrays academic assets in Pfizer defence
Reference Reuters 18 May 2014
Year: 2014
Type: Funding
Subject: The Reuters news agency reports further detail of a joint research fund between the MRC Laboratory of Molecular Biology and AstraZeneca
Keywords: AstraZeneca; Pfizer; collaboration; joint fund; Hugh Pelham; biotech; MedImmune; Cambridge Antibody Technology; Mene Pangalos
Photographs:Author: Cambridge News
Title: Sir Hugh Pelham explains why pledge from the MRC LMB and AstraZeneca is good news for Cambridge
Reference Cambridge News 20 May 2014
Year: 2014
Type: Funding
Subject: Sir Hugh Pelham talks about why pledge from the MRC LMB and AstraZeneca could mean good news for Cambridge
Keywords: AstraZeneca; joint fund; Menelas Pangalos; Hugh Pelham; Pfizer; collaborations; Big Pharma
Photographs: Hugh Pelham; new buildingAuthor: Buchan, Lizzy
Title: Nobel prize winning Cambridge scientist Max Perutz given new stamp of approval
Reference Cambridge News 20 May 2014
Year: 2014
Type: Miscellaneous
Subject: Max Perutz, who was honoured on the centenary of his birth with a Royal Mail Stamp, and apostmark created for the occasion, which will appear on letters and parcels delivered around Cambridge this week
Keywords: Max Perutz; stamp; postmark; Royal Mail; ‘Remarkable Lives’
Photographs:Author: Baker, Isabel
Title: Imaging the unimaginable
Reference MRC Network Summer 2014
Year: 2014
Type: Science
Subject: The latest advances in electron microscopy at the LMB are featured in MRC’s Network magazine, showing how collaboration and complementary expertise have led to a structural biology breakthroug
Keywords: Max Perutz; Venki Ramakrishnan; X-ray crystallography; electron microscopy (EM); John Walker; Ribsomes; Wasi Faruqi; Richard Henderson; Mitochondria; Sjors Scheres; Israel Sanchez; Alexey Amunts; mitoribosomes; Xiaochen Bai; Alan Brown; Garib Murshudov; Fei Long; Paul Emsley; Tanweer Hussain; Jose Llacer; RELION; REFMAC
Photographs: Image of how single nucleotides and ions can be distinguished using cryo-EM; The structure of the yeast mitoribosomal large subunitAuthor: Baker, Isabel
Title: My Work Space - Lori Passmore
Reference MRC Network Summer 2014
Year: 2014
Type: History - Reminiscences
Subject: Interview with the LMB’s Lori Passmore, as she explains why it is such a fascinating time for electron microscopy
Keywords: Lori Passmore; cryo-EM; Nobel chocolate coin; Venki Ramakrishnan; coasters; Graphene; Chris Russo; Fanconi anaemia (FA); Eeson Rajendra; KJ Patel; new office
Photographs: Lori in her office; coaster; Light box; Nobel chocolate coin; copper foil; Picture of DNA by childAuthor: Stephen Perse Foundation Senior School
Title: Crystals and helices everywhere
Reference Stephen Perse Senior School News 8 July 2014
Year: 2014
Type: Miscellaneous
Subject: Pupils who grew crystals in their Chemistry lessons and won first prize in the Eastern Region Crystal Growing Competition for Key Stage 3 pupils. The prizewinners had a tour of the LMB and took part in experiments.
Keywords: Crystal Growing Competition; Stephen Perse Senior School; Sam Wynne
Photographs: Group photo of year 7 winners; Crystals grown in compertitionAuthor: The Institute of Cancer Research
Title: Scientists map one of most important proteins in life - and cancer
Reference The Institute of Cancer Research 24 July 2014
Year: 2014
Type: Science
Subject: David Barford and his group, and at the ICR in London, have used cryo-EM to reveal the secondary structure of a vital protein in cell division: the human anaphase-promoting complex (APC/C
Keywords: David Barford; cancer; (APC/C); The Institute of Cancer Research; Cytokinesis; anaphase; Alpha-helix rods; proteins; Paul Workman; Cancer Research UK; cryo-EM
Photographs:Author: Heaven, Douglas
Title: Worm neuron hack to probe the mysteries of our brains
Reference New Scientist 23 July 2014
Year: 2014
Type: Science
Subject: Hijacking how neurons of nematode worms are wired is the first step in an approach that could revolutionise our understanding of brains and consciousness
Keywords: Bill Schafer; nematode worm; brain hack; neurons; optogenetics; synapses
Photographs:Author: Rado-Trilla, Nuria
Title: Journal allows authors to update their research
Reference Times Higher Education 15 August 2014
Year: 2014
Type: Science
Subject: The open access journal eLife has launched a new type of article that will allow authors to report significant additions to their original research
Keywords: Sjors Scheres; journal; publish; cryo-microscopy (EM); eLife; open access; “research advance”; research
Photographs:Author: Sloyan, Victoria
Title: John Sulston: a pioneer of genomics
Reference Wellcome Library 16 July 2014
Year: 2014
Type: History - Reminiscences
Subject: Archive papers of former LMB scientist John Sulston have been added to the Wellcome Library.
Keywords: John Sulston; Wellcome Trust; nematode worm; archive; Sydney Brenner; C. elegans; neurons; Bob Horvitz; ventral cord; Judith Kimble; Alan Coulson; Bob Waterston; genomic mapping; Fortran
Photographs: John Sulston in lab; Drawings of c. elegans by John; annotated computer logAuthor: Shaw, Jenny
Title: Alan Coulson’s Science of Collaboration
Reference Wellcome Library 17 July 2014
Year: 2014
Type: History - Reminiscences
Subject: Archive papers of former LMB scientist Alan Coulson have been added to the Wellcome Library.
Keywords: Alan Coulson; archive; Wellcome Library; Fred Sanger; John Sulston; dideoxy sequencing; human genome; ‘Sanger sequencing’; Sanger Centre
Photographs: Alan Coulson standing beside the physical mapping of the C.elegans nematodeAuthor: Infection Control Today
Title: Discovery Could Help Turn Antibiotic Into Antimalarial Drug
Reference Infection Control Today 3 September 2014
Year: 2014
Type: Science
Subject: Scientists in Melbourne and collaborators led by Sjors Scheres have made progress toward new antimalarial drugs, after revealing how an antibiotic called emetine blocks the molecular machinery that produces the proteins required for malaria parasite survival.
Keywords: Antimalarial; antibiotic; Walter and Eliza Hall Institute; emetine; Sjors Scheres; Wilson Wong; parasite; malaria; plasmodium; pactamycin; cryo-EM
Photographs: Image of Dr Wilson WongAuthor: Diamond Light Source Ltd.
Title: New film premiers sparkling history of crystallography
Reference Diamond 17 September 2014
Year: 2014
Type: Miscellaneous
Subject: A new documentary, charting the history of crystallography tells a fascinating story of a scientific technique that is revealing many of life’s most beautiful secrets. The film includes material from the LMB Archive.
Keywords: Crystallography; Bragg’s Law; Diamond Light Source; Royal Institution of Great Britain; documentary; International year of Crystallography; Tom Blundell
Photographs: Sir Tom Blundell; Lady Bragg’s Dress with design based crystallography pattern; Patience Thompson with her father Sir Lawrence BraggAuthor: Butt, Vicky
Title: Worm Watch Lab: one year on
Reference MRC Insight 24 September 2014
Year: 2014
Type: Science
Subject: It’s been more than a year since the launch of Worm Watch Lab, a citizen science project involving the William Schafer in which members of the public watch videos of tiny nematode worms, to contribute to a neuroscience study.
Keywords: Worm Watch; nematode worm; c. elegans; citizen science; William Schafer; Zooniverse
Photographs:Author: Heilesen, Lisbeth
Title: Brian Clark has died - marking the end of an era
Reference Aarhus University 9 October 2014
Year: 2014
Type: Obituary
Subject: Professor Brian Clark, member of LMB Scientific Staff 1964-1974, and founder of structural biology research at Aarhus University, died on 6 October 2014 aged 78 years.
Keywords: Brian Clark; Francis Crick; Sydney Brenner; Aaron Klug; Aarhus University; protein biosynthesis; Kjeld Marcker; EF-Tu
Photographs: Brian F.C. Clark (photo: Lisbeth Heilesen, Aarhus University)Author: Reuters
Title: Bicycle Therapeutics Announces £20M ($32M) Million Financing for Drug Development
Reference Reuters 14 October 2014
Year: 2014
Type: Biotechnology
Subject: Bicycle Therapeutics, founded as a spin out company from the LMB by Sir Greg Winter and Christian Heinis, has secured £20m equity financing to develop bicycle drug candidates for cancer treatment.
Keywords: Bicycle Therapeutics; financing; bicycle-drug conjugates (BDCs); Greg Winter; Christian Heinis; bicyclic peptides
Photographs: