Author: University of Massachusetts Medical School
Title: Raúl Padrón Elected to National Academy of Sciences
Reference University of Massachusetts Medical School March 2019
Year: 2019
Type: Alumni - Awards & Prizes
Subject: Raúl Padrón, Senior Research Scientist in Radiology, has been elected to the National Academy of Sciences as a foreign associate
Keywords: Raúl Padrón; elected; National Academy of Science; cryo-EM; award; alumni; Roger Craig; foreign associate; muscle structure
Photographs: Raúl with electron microscope; Raúl with Roger CraigAuthor: Ferry, Georgina
Title: Sydney Brenner obituary
Reference The Guardian 5 April 2019
Year: 2019
Type: Alumni - Obituary
Subject: Georgina Ferry’s obituary for Sydney Brenner who died on 5 April 2019
Keywords: Sydney Brenner; “enfant terrible of molecular biology”; C. elegans; John Sulston; Robert Horvitz; Francis Crick; Leslie Barnett; genetics; Salk Institute; La Jolla; John White; Nicol Thompson; worm; genome
Photographs: Sydney in his officeAuthor: Watts, Geoff
Title: Obituary Aaron Klug
Reference The Lancet (Vol 392) 15 December 2019
Year: 2019
Type: Obituary
Subject: Aaron Klug obituary from the Lancet
Keywords: Aaron Klug; tobacco mosaic virus; Rosalind Franklin; Richard Henderson; “polymath”; zinc fingers; Tony Crowther; Alzheimer’s disease; tau protein; tangles; genes; genome sequencing; President Royal Society; Paul de Kruif; Microbe Hunters
Photographs: Aaron in office (science photo library)Author: Vilcek. Foundation
Title: Ruth Lehmann - 2021 Vilcek Prize in Biomedical Science
Reference Vilcek Foundation 26 October 2020
Year: 2020
Type: Alumni - Awards & Prizes
Subject: Ruth Lehmann, a former postdoctoral visitor with Michael Wilcox and Peter Lawrence in the LMB’s Cell Biology Division, has been awarded the 2021 Vilcek Prize in Biomedical Science, for unraveling the molecular basis by which germ cells, which give rise to sperm and egg cells, are formed.
Keywords: Ruth Lehmann; germ cell; life cycle; Michael Wilcox; Peter Lawrence; genetics; egg cytoplasm; alumni; prize; award; Developmental Biology
Photographs: Portrait picture of Ruth; Ruth at age 1 with brother and mother, Ruth at the age of 25 at a conference; Ruth in the 1990; Ruth with post grad and postdoc in labAuthor: Peplow, Mark
Title: Cryo-electron microscopy reaches resolution mileston
Reference C&EN 27 September 2020
Year: 2020
Type: Science
Subject: Detailed protein structures are fueling drug-discovery efforts
Keywords: Cryo-EM; Richard Henderson; GABAA: COVID-19; Titan Krios microscopes; X-ray crystallography; Radu Aricescu; Sjors Scheres; Christopher Russo; SARS-CoV-2; 100 keV; protein
Photographs:Author: Devlin, Hannah
Title: Sir John Sulston, pioneering genome scientist, dies aged 75
Reference The Guardian 9 March 2018
Year: 2018
Type: Obituary
Subject: The Guardian obituary for Sir John Sulston
Keywords: John Sulston; obituary; Human Genome Project; Wellcome Sanger Institute; nematode; Caenorhabditis elegans; genes; Meccano
Photographs: John Sulston head shotAuthor: Service, F. Robert
Title: Protein evolution earns chemistry Nobel
Reference Science Magazine 12 October 2018
Year: 2018
Type: Awards & Prizes
Subject: Nobel Prize in Chemistry that was awarded to Greg Winter with Frances Arnold and George Smith evolved the use of biological molecules.
Keywords: Greg Winter; auto-immune diseases; cancer; viruses; antibodies; evolution; prize; TNF-a; adalimumab; Humira; phage; ethanol fuel; biomolecules; gene
Photographs:Author: Ramakrishnan, Venki: Henderson, Richard
Title: Thomas A. Steitz (1940-2018)
Reference Science 23 November 2018
Year: 2018
Type: Alumni - Obituary (Retrospective)
Subject: Thomas Steitz the biochemistry giant who illuminated ribosome structure dies
Keywords: Thomas A. Steitz; Max Perutz; Joan Argetsinger Steitz; David Blow; crystallography; trypsin; aspartic acid; Brian Hartley; creative science; CAP repressor; 50S ribosome subunit; “jewel in the crown”; peptidyl transfer; obituary; hexokinase; RNA polymerases
Photographs: Picture of Thomas SteitzAuthor: Marshall, Michael
Title: Charles Darwin’s hunch about early life was probaly right
Reference BBC Future 11 November 2020
Year: 2020
Type: Science
Subject: BBC FUTURE article looking back at origin of life research breakthroughs, including key research by John Sutherland that utilised UV light to form the building blocks of life from simple carbon-based chemicals
Keywords: Charles Darwin; natural selection; On the Origin of Species; Claudia Bonfio; amino acids; nucleobases; protein; John Sutherland; building blocks; “fluctuating volcanic hot spring pool”; meteorite crater; wet-dry cycles
Photographs:Author: Highfield, Roger
Title: Coronavirus: The Spike
Reference Science Museum Group 25 November 2020
Year: 2020
Type: Science
Subject: Many COVID-19 drugs, vaccines and tests depend on ‘the spike’. Roger Highfield, Science Director, talks to John Briggs and finds out all there is to know about 2020’s most infamous protein
Keywords: COVID-19; John Briggs; SARS-CoV-2; atomic level; virus; cryo-EM; X rays; 3D reconstruction; spike; coronavirus; angiotensin-converting enzyme 2 (ACE2); ‘Brownian motion’; ‘hook’; receptor binding domain (RBD); hijack the cell; glycoprotein; neutralising antibodies; immune system; vaccines; RNA; ‘vectors’; adenovirus; Julian Sale; ‘druggable pocket’; Radu Aricescu; Andrew Carter; Leo James; Yorgo Modis; Jan Löwe; Sjors Scheres; diagnostic reagent; D614G; immunoglobulin G (IgG); IgM; IgA; John Meurig Thomas; ‘Nobel prize factory’
Photographs: Various images of coronavirusAuthor: Barr, Sabrina
Title: When you eat could be just as important as what what you eat for prevention of disease
Reference Independent 25 April 2019
Year: 2019
Type: Science
Subject: The time of day that you eat could be just as important to your wellbeing as the food you consume, a new study has found.
Keywords: circadian rhythm; “Period”; cardiovascular disease; type 2 diabetes; body clock; insulin; John O’Neill; food; wellbeing; meal timings; cellular clocks
Photographs:Author: Weeks, Mark
Title: Sir John Sulston (1942-2018)
Reference Wellcome News 9 March 2018
Year: 2018
Type: Obituary
Subject: The death of Sir John Sulston, and how he was an outstanding figure in UK biological and medical science and in Wellcome’s history.
Keywords: John Sulston; obituary; Wellcome Trust Sanger Institute; genome sequencing; Human Genome Project; nematode worm; C. elegans
Photographs:Author: Royal Society
Title: Sir Gregory Winter CBE FMedSci FRS Blockbuster drugs: from fantasy to reality
Reference Royal Society 29 November 2018
Year: 2018
Type: History - Reminiscences
Subject: An entire new class of drugs was launched as a result of technology developed by Sir Gregory Winter
Keywords: Gregory Winter; human antibodies; “humanise”; genetic engineering; Herceptin; Avastin; cancer; “pie-in-the-sky”; Cambridge Antibody Technology; Humira; AstraZeneca; Domantis; Bicycle Therapies; autoimmune diseases
Photographs: Sir Gregory informal shotAuthor: Cookson, Clive
Title: Stable research funding drives Britain’s ‘Nobel factory’
Reference The Financial Times 7 December 2018
Year: 2018
Type: Funding
Subject: How stable long-term funding contributes to the discoveries made by the LMB
Keywords: Greg Winter; Jan Löwe; “Nobel factory”; Richard Henderson; cryo-EM; funding model; Madeline Lancaster; cerebral organoids; mini brains; Alzheimer’s; autism; Greg Jefferis; Mick Hastings; circadian rhythms; molecular clocks; suprachiasmatic nucleus; antibody-based drugs; collaborative interaction
Photographs: Scientists in LMB lab; Jan Löwe in his office; Greg Winter outside Trinity College; inside the atrium of the buildingAuthor: Bates, Alex
Title: Size Matters: Mapping a Miniature Brain
Reference BlueSci Lent 2018
Year: 2018
Type: Science
Subject: Alex Bates discuses his PhD on mapping a small part of the fly brain
Keywords: Alex Bate; Juvenile fruit fly brain; QI; Alan Davis; Drosophila melanogaster; vinegar fly; ataxia; Alzheimer’s disease; Parkinson’s disease; electron microscopy; caenorhabditis elegans; ‘Tracey’; “Google maps’ of brains; neurons; mapping; penis brain; phallic;‘connectomic’
Photographs:Author: YaleNews
Title: Nobel laureate Thomas A. Steitz dies, mapped the structure of the ribosome
Reference YaleNews 10 October 2018
Year: 2018
Type: Alumni-Obituary
Subject: Thomas A. Steitz, Sterling Professor of Molecular Biophysics and Biochemistry at Yale and one of three winners of the 2009 Nobel Prize in Chemistry, died 9 October 2018
Keywords: Thomas A. Steitz; ribosome; antibiotics; Joan Steitz; obituary; X-ray crystallography
Photographs: Thomas A. Steitz portrait; Thomas at Nobel Prize ceremonyAuthor: Williamson, Lorna
Title: Richard Henderson’s Nobel Prize
Reference The Bulletin of the Royal College of Pathologists July 2018
Year: 2018
Type: Awards & Prizes
Subject: New developments in imaging individual molecules could unlock the structural basis of normal and abnormal biochemical pathways. rcpath, celebrate the work of Richard Henderson.
Keywords: Richard Henderson; cryo-EM; Nigel Unwin; bacteriorhodopsin; X-ray crystallography; atomic structures; Chris Tate; G pro- tein– coupled receptors (GPCRs); LifeArc; Heptares Therapeutics Ltd (HTL); rapid freezing
Photographs: Richard holding ball and spoke modelAuthor: Taylor, Mark
Title: Football is just a branch of science for Cambridge United Women midfielder Gisela Otten
Reference Cambridge Independent 7 December 2020
Year: 2020
Type: Miscellaneous
Subject: Gisela Otten, post-doctoral researcher in Felix Randow’s group in the LMB’s PNAC Division, talks to the Cambridge Independent about her route to joining Cambridge United WFC and combining this with her scientific career
Keywords: Gisela Otten; Cambridge United women’s team; midfield; football; bacterial infections; Church; Felix Randow
Photographs: Gisela playing foodball for United; Head shot of GiselaAuthor: Marshall, Michael
Title: How the first life on Earth survived its biggest threat-water (The water paradox and the origins of life)
Reference Nature 9 December 2020
Year: 2020
Type: Science
Subject: Living things depend on water, but it breaks down DNA and other key molecules. So how did the earliest cells deal with the water paradox?
Keywords: NASA; Perseverance; Jezero Crater; Lake; liquid water; John Sutherland; Mars; first biological cells; carbon based chemicals; wet and dry; Primordial soup; cyanamide; proteins; lipids; warm pond; Claudia Bonfio; prebiotic chemistry
Photographs:Author: Ferry, Georgina
Title: Women of the Nobel factory share their stories
Reference Nature 15 December 2020
Year: 2020
Type: Book Review
Subject: From sequencing to stardom — alumnae of the Laboratory of Molecular Biology reflect on how they succeeded in science for Kathleen Weston’s book
Keywords: Kathleen Weston; ‘sexist ads’; Ahead of the Curve; book review; “discrimination against mediocrity”; interviews; women; Elizabeth Blackburn; Sarah Teichmann; Joan Steitz; Fred Sanger; Max Perutz; Daniela Rhodes; Mariann Bienz; Hugh Pelham; Aaron Klug; Melina Schuh; ‘leaky pipline’; unconscious bias; impostor syndrome; salary disparities
Photographs:Author: British Neuroscience Association
Title: 2020 BNA Prize Winners!
Reference British Neuroscience Association 14 December 2020
Year: 2020
Type: Awards & Prizes
Subject: Alexander Bates wins the 2020 British Neuroscience Association Postgraduate Award
Keywords: Alexander Bates; award; Greg Jefferis; ‘connectomics’; British Neuroscience Association
Photographs: Alexander BatesAuthor: Parshley, Lois
Title: The many strange long-term symptoms of Covid-19, explained
Reference Vox 15 December 2020
Year: 2020
Type: Science
Subject: Article looking at the varied long-term effects of Covid-19 and the clues that latest research offers into what might be causing all the symptoms – including Madeline Lancaster lab’s study showing that SARS-CoV-2 can damage cells in the brain’s choroid plexus
Keywords: Covid-19; Long Covid; SARS-CoV-2; coronavirus; neurological symptoms; Madeline Lancaster; choroid plexus; postural orthostatic tachycardia syndrome (POTS); neuro-inflammation; cytokine storms; hyperinflammation; post-viral chronic fatigue syndome; deep vain thromboses; pulmonary problems
Photographs: Hospital picturesAuthor: Kiessling, Tilmann
Title: EMBO welcomes thirty Young Investigators
Reference EMBO 1 December 2020
Year: 2020
Type: Alumni - Awards & Prizes
Subject: LMB Alumnus Tanmay Bharat is among 30 life science researchers within their first four years as group leaders to become EMBO Young Investigators
Keywords: Tanmay Bharat; EMBO Young Invetigators; award; alumni
Photographs:Author: Cristo, Inês
Title: Cell scientist to watch - Hayley Sharpe
Reference Journal of Cell Science 8 December 2020
Year: 2020
Type: Alumni - Career Structure
Subject: Hayley Sharpe, a former PhD student with Sean Munro’s group in the Cell Biology Division, is interviewed by the Journal of Cell Science about her career so far, how she ended up studying phosphatases
Keywords: Hayley Sharpe; alumni; Sean Munro; Peter Lawrence; Babraham Institute; ultimate Frisbee; phosphatases; EMBO Young Investigator; Lister Institute Research Prize; career; lockdown
Photographs: Hayley Sharpe; Hayley with husband cyclingAuthor: Mogrify/MRC Laboratory of Molecular Biology
Title: Mogrify enters research collaboration with the MRC Laboratory of Molecular Biology
Reference Mogrify Press Release 11 January 2020
Year: 2020
Type: Science
Subject: Exploratory research project aims to develop novel protein expression systems via cell reprogramming
Keywords: Mogrify; ex vivo cell therapies; protein expression systems; LifeArc; Julian Gough; collaboration; project
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