How did organelles evolve within complex cells?

Knowable magazine covers competing theories as to how organelles such as the nucleus and endoplasmic reticulum came to exist within complex cells. They include the ‘inside-out’ approach from Buzz Baum, Group Leader in the LMB’s Cell Biology Division, who posits that long protrusions from ancient archaeal cells slowly enclosed neighbouring alphaproteobacterium to eventually create internal membrane compartments. More…