LMB 365 – Day 192

Liz Miller’s lab in Cell Biology uses yeast colony arrays, seen here on day 192 of #LMB365, to test growth of >5000 genetic mutants all at once. They pin the yeast cells at 384 density to capture the full genome on only 15 plates and quantify colony size to measure growth defects. Using such high throughput screening, Liz’s lab aims to identify new players in protein quality control in the secretory pathway.